X. Chen

The paper shows IGF2BP proteins rapidly cluster under osmotic stress, initiating stress granule formation before other proteins, and identifies the molecular mechanisms involved.

This study investigates how HMGB1 and RAGE promote tumor growth in autophagy-deficient livers by altering the tumor microenvironment and mitochondrial function.

This study shows that reducing SIRT2 rescues GARS-induced neuropathy in a Drosophila model by restoring acetylated tubulin levels and axonal transport.

This study shows that deoxynivalenol (DON) promotes PEDV infection and worsens gut barrier injury by inducing autophagy and impairing innate immunity.

The paper identifies genetic variants associated with invasion success in Drosophila suzukii using a new statistical method to correct for population structure.

This study identifies and characterizes the kisspeptin system in the sea cucumber Apostichopus japonicus, revealing its existence and function in a non-chordate species.

The paper shows that drug combination transcriptional responses are not simply additive and develops a prediction algorithm with 0.84 AUROC for synergistic combinations.

The paper uses SHAPE profiling to study RNA structure in Arabidopsis nuclei and identifies structural features linked to mRNA splicing and polyadenylation.

The paper presents a large multi-omic cohort of 2,183 adults to identify correlations between gut microbiome features and various health-related factors, validated in an additional cohort.

This study shows BMP9 induces osteogenic differentiation in GC-1spg cells through upregulated markers and in vivo bone formation.

This study shows that alternative splicing of FXR1 regulates its function in muscle development by controlling RNA-dependent condensates and disease-related mis-splicing.

This study examines flight morphology variation in stick insects, finding that intermediate wing sizes are rare and that wing and body size are inversely correlated.

This study examines how modified sialic acids in mucus and erythrocytes affect influenza A virus HA and NA functions, finding that these modifications inhibit viral binding and cleavage.

This study sequenced 358 brown planthopper genomes to reveal genetic structure and dispersal patterns, identifying five genetic groups and highlighting Southeast Asia as a major source for East Asian populations.

This study identifies determinants of sialoglycan-binding selectivity in Siglec-like adhesins and creates engineered binding proteins for specific glycan recognition.

This study identifies MYPT1 O-GlcNAcylation as a regulator of centrosome disjunction during mitosis, showing that it modulates Plk1 activity and affects cell cycle progression.

This study evaluates a hyperspectral model for estimating aboveground biomass in Khorchin grassland using field and TM8 data, finding an exponential relationship with R2 = 0.636.

The paper introduces a fluorescent reporter to measure cell cycle speed in single cells using one snapshot, demonstrating its application in hematopoietic cells and solid tissues.

This study shows CpG-ODN 2007 reduces mortality and toxicity in zebrafish infected with Vibrio vulnificus and modulates immune gene expression.

This paper shows overexpression of ELO2 in yeast increases complex sphingolipids, improving osmotic tolerance and cell survival under high salt conditions.

This paper shows that the Arabidopsis receptor kinase STRUBBELIG regulates the cellular response to cellulose deficiency by affecting reactive oxygen species, stress gene induction, and cell wall integrity.

This study shows that effector T cells use inosine as an alternative carbon source under glucose restriction, enhancing anti-tumor function and bypassing tumor-imposed metabolic limitations.

This study analyzes the vagino-cervical microbiome of 516 women using metagenomic shotgun sequencing to explore how pregnancy, delivery, and contraception influence microbiome composition.

The paper was withdrawn due to lack of full author consent and is not intended for citation.

The paper examines 3D chromatin changes in T-ALL, identifies TAD fusion events linked to oncogene activation, and shows drug treatments can restore some interactions.

This study uses super-resolution microscopy to reveal the cup-shaped structure of the autophagic initiation machinery, showing FIP200 scaffolds this structure before LC3 lipidation.

This study shows that neogambogic acid inhibits osteosarcoma by targeting the USP9x/SOX2 axis through ubiquitin proteasome-mediated degradation of SOX2.

This study investigates the functional divergence of OsFIE1 and OsFIE2 in rice, showing OsFIE1 is involved in late seed development while OsFIE2 is critical for early seed development and cellularization.

The paper develops a machine learning framework to predict thermostable mutations for GPCRs, achieving higher success rates than systematic alanine scanning.

This study shows that healthy individuals exhibit loss aversion during effort-based decision-making, and this effect is reduced in medicated Parkinson's disease patients, suggesting a dopamine-dependent mechanism.