X. Xie

The paper assesses cross-neutralization of Omicron BA.1 sera against BA.2, BA.3, and a pre-Omicron strain, finding reduced neutralizing titers against heterologous variants.

This study assesses the neutralization of Omicron sublineages BA.1, BA.2, and BA.3 by BNT162b2 vaccine sera, finding reduced neutralization compared to the original SARS-CoV-2 strain.

This paper describes a live-attenuated SARS-CoV-2 vaccine candidate with deleted ORFs that shows reduced replication and attenuation in animal models, and reports its protective efficacy against wild-type virus challenge.

This study assesses the antiviral activity of remdesivir and GS-441524 against multiple SARS-CoV-2 variants, finding they remain effective against Delta, Omicron, and other variants.

This study compares sterilization methods for fish surrogacy, finding germ cell-depleted recipients most effective for successful germ cell transplantation and reproductive output.

This study engineers bispecific antibodies against SARS-CoV-2, showing that one design outperforms a cocktail in neutralizing activity and breadth against variants.

This study evaluates the neutralization of Omicron SARS-CoV-2 by two or three doses of the BNT162b2 vaccine, showing increased neutralization with three doses but reduced durability over time.

This study identifies novel viral genomic components and evolutionary patterns using conserved untranslated regions (UTRs) and UTR-backed iterative BLASTn in multipartite viruses.

This study assesses cross-neutralization against Omicron SARS-CoV-2 from prior non-Omicron infections and finds significantly lower neutralization titers compared to the original strain.

This study evaluates how well antibodies from mRNA vaccines neutralize SARS-CoV-2 variants, finding that Omicron shows the most escape but booster doses maintain moderate neutralizing activity.

This study identifies integrin mechanotransduction as essential for directing cytotoxic secretion at the immune synapse, showing that mechanical forces from LFA-1 guide lytic granule fusion and cytotoxicity.

The paper assesses the neutralization ability of BNT162b2-elicited sera against SARS-CoV-2 variants, finding that all sera neutralize variants to titers of ≥80, indicating vaccine effectiveness against emerging strains.

This study shows that immunization with different SARS-CoV-2 variant spikes leads to varying neutralizing kinetics and magnitudes against other variants, with significant differences in titers between homologous and heterologous variants.

This study identifies BSB, an ancestral strigolactone in bryophytes, which functions as a rhizosphere signal for AM symbiosis and was later co-opted as a plant hormone.

This study identifies the P681R mutation in the Delta variant's spike protein as critical for enhanced viral replication compared to the Alpha variant through increased furin cleavage of the spike protein.

This study shows miR-206 reduces estrogen-induced proliferation and invasion of ER-α36 positive gastric cancer cells by targeting CDK14.

This study shows that a single mucosal dose of the live attenuated RSV-based vaccine MV-014-212 protects non-human primates from SARS-CoV-2 infection by reducing viral shedding and inducing neutralizing antibodies.

This study identifies DENV-4 in Florida mosquitoes without human cases, shows it can infect mosquitoes and transmit vertically, suggesting undetected circulation and environmental maintenance.

The paper uses phylogenetic network analysis to show that the SARS-CoV-2 VOC202012/01 variant originated through recombination, not step-wise mutations.

The paper presents cryo-EM structures of the ghrelin receptor bound to ghrelin and GHRP-6, revealing the binding pocket for the octanoyl group and providing insights for drug design.

This study uses deep learning to classify cell sub-populations based on mechanical properties measured through deformability cytometry with high accuracy.

This study shows iminosugar glucosidase inhibitors suppress SARS-CoV-2 replication in tissue culture and enhance Remdesivir's effect.

This study creates a mouse-adapted SARS-CoV-2 strain that protects mice from lethal SARS-CoV challenge, demonstrating cross-strain immunity.

This paper identifies Rab5a as a host factor that RSV activates to suppress IRF1-dependent IFN-λ production, thereby reducing antiviral immunity in airway epithelial cells.

The paper shows the N501Y spike mutation in SARS-CoV-2 enhances viral transmission in hamsters and human airway cells by increasing receptor binding affinity.

This study evaluates the protective efficacy of modified miniproteins against SARS-CoV-2 in mice, showing reduced viral burden and prevention of lung disease.

This study shows O-GlcNAc modification of MTA1 enhances its chromatin binding and transcriptional activity, aiding breast cancer cells in adapting to genotoxic stress.

The paper evaluates the neutralization effect of BNT162b2 vaccine-elicited sera against SARS-CoV-2 variants with specific spike mutations.