Author
X. Zhu
Dalian University of TechnologyPrimary ORCID profile (0009-0006-1930-8912 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2017-2026 · peak 33/yrCo-Author Collaboration Network
10 top collaborators · 39 mutual co-author links120 papers
Recent·Most cited
- BiophysicsbioRxivPreprint
Structure of the Cytoplasmic Ring of the Xenopus laevis Nuclear Pore Complex
G. Huang, Y. Zhang, X. Zhu…·Y. Shi
The paper presents a high-resolution cryo-EM structure of the Xenopus laevis nuclear pore complex cytoplasmic ring, revealing new structural features and interactions.
- Animal Behavior & CognitionbioRxiv
Glycyrrhizic acid improves cognitive levels of aging mice by regulating T/B cell proliferation
R. Jiang, J. Gao, J. Shen…·H. Liu
This study shows that glycyrrhizic acid improves cognitive function in aged mice by enhancing T and B cell proliferation and blood perfusion.
DOI 10.3389/fnagi.2020.570116 - MicrobiologybioRxiv
A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV
M. Yuan, N. C. Wu, X. Zhu…·I. A. Wilson
Structural study of a cross-reactive SARS antibody reveals a conserved epitope on the SARS-CoV-2 receptor-binding domain.
DOI 10.1126/science.abb7269 - Cancer BiologyLeukemiaPeer-reviewed
Mesenchymal stem cells suppress leukemia via macrophage-mediated functional restoration of bone marrow microenvironment
C. Xia, T. Wang, H. Cheng…·J. Wang
This study shows that intra-BM MSC transfusion restores the BM microenvironment, suppresses leukemia, and reprograms macrophages to reduce tumor burden.
DOI 10.1038/s41375-020-0775-3 - MicrobiologyBiotechnology for BiofuelsPeer-reviewed
The anaerobic digestion microbiome: a collection of 1600 metagenome-assembled genomes shows high species diversity related to methane production
S. Campanaro, L. Treu, L. M. Rodriguez Rojas…·I. Angelidaki
This study compiles 1,635 metagenome-assembled genomes from 134 biogas reactor datasets to explore microbial diversity and functional traits in anaerobic digestion.
DOI 10.1186/s13068-020-01679-y - Evolutionary BiologybioRxivPreprint
Polyploidization enhancing genetic recombination of the ancestral diploid genome in the evolution of hexaploid wheat
This study shows that hexaploidization in wheat enhances genetic recombination of the ancestral diploid genome, increasing evolutionary potential and aiding wheat's global spread.
DOI 10.1101/2020.02.21.958991 - BioengineeringbioRxiv
Single and binary protein electroultrafiltration using poly(vinyl-alcohol)-carbon nanotube (PVA-CNT) composite membranes
R. Yeung, X. Zhu, T. Gee…·V. G. J. Rodgers
The paper evaluates electroultrafiltration using PVA-CNT composite membranes for protein separation, finding temporary improvements in selectivity and sieving compared to conventional membranes.
DOI 10.1371/journal.pone.0228973 - BiochemistrybioRxiv
Disease mutation study identifies essential residues for phosphatidylserine flippase ATP11A
K. Sun, W. Tian, W. Liu…·X. Zhu
The paper identifies essential residues in ATP11A for its expression and flippase activity through mutation analysis and functional assays.
DOI 10.1155/2020/7342817 - PathologybioRxivPreprint
Human Tau Isoform Aggregation and Selective Detection of Misfolded Tau from Post-Mortem Alzheimer's Disease Brains
This study investigates human tau isoform aggregation in Alzheimer's disease, showing 3R tau aggregates faster than 4R and identifies key domains for aggregation, while demonstrating the use of RT-QuIC to detect misfolded tau.
DOI 10.1101/2019.12.31.876946 - Plant BiologybioRxivPreprint
GABA signalling in guard cells acts as a 'stress memory' to optimise plant water loss
B. Xu, Y. Long, X. Feng…·M. Gilliham
This study identifies GABA as an endogenous plant signal that regulates stomatal movement and drought tolerance by inhibiting anion transporters in guard cells.
DOI 10.1101/2019.12.22.885160 - Cell BiologybioRxiv
Cep57 and Cep57l1 cooperate to recruit the Cep63-Cep152 complex for centriole biogenesis
H. Zhao, S. Yang, X. Duan…·X. Yan
This study shows that Cep57 and Cep57l1 recruit the Cep63-Cep152 complex to mother centrioles, enabling centriole duplication.
DOI 10.1242/jcs.241836 - Cell BiologybioRxiv
Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM
W. Zheng, F. Li, Z. Ding…·Y. Cong
The paper reveals the structure and composition of the mouse axonemal radial spoke head using cryo-EM, showing distinct subunit composition and organization compared to Chlamydomonas.
- Cancer BiologybioRxiv
Research of the mechanism on miRNA193 in exosomes promotes cisplatin resistance in esophageal cancer cells
X. Zhu, X. Huang, X. Ma, Q. Zhang
This study identifies miRNA193 in exosomes as a mediator of cisplatin resistance in esophageal cancer cells by regulating the cell cycle and inhibiting apoptosis.
DOI 10.1371/journal.pone.0225290 - BioengineeringbioRxivPreprint
A modular microreservoir for active implantable drug delivery
F. Forouzandeh, X. Zhu, N. N. Ahamed…·D. A. Borkholder
This paper presents a refillable, scalable microreservoir for implantable drug delivery, demonstrating its effectiveness in subcutaneous implantation and integration with micropumps for targeted drug infusion.
DOI 10.1101/762716 - ImmunologybioRxiv
African Salmonella Typhimurium sequence type 313 lineage 2 evades MAIT cell recognition by overexpressing RibB
L. Preciado-Llanes, A. Aulicino, R. Canals…·A. Simmons
The paper shows African S. Typhimurium lineage 2 strains evade MAIT cell recognition by overexpressing ribB, which may contribute to their pathogenicity.
DOI 10.1073/pnas.2007472117 - Evolutionary BiologybioRxivPreprint
Evolutionary changes of phosphoenolpyruvate transporter (PPT) during the emergence of C4 photosynthesis
M.-J. A. Lyu, Y. Wang, J. Jiang…·X. Zhu
This study examines evolutionary changes in the phosphoenolpyruvate transporter (PPT) during C4 photosynthesis emergence, identifying shifts in expression, light responsiveness, and cis-element acquisition in PPT1.
DOI 10.1101/713537 - ImmunologybioRxivPreprint
A distinct neutrophil population invades the central nervous system during pancreatic cancer
K. G. Burfeind, X. Zhu, M. A. Norgard…·D. L. Marks
This study identifies a novel neutrophil population invading the brain during pancreatic cancer, mediated by CCR2/CCL2 and P2RX7, leading to anorexia and muscle catabolism.
DOI 10.1101/659060 - EcologybioRxiv
Soil and vegetation conditions changes following the different sand dune restoration measures on the Zoige Plateau
J. Luo, D. Deng, L. Zhang…·J. Zhou
The paper evaluates sand dune restoration methods on the Zoige Plateau, finding that sandbag and wicker with seeding improved soil conditions more than seeding alone.
DOI 10.1371/journal.pone.0216975 - Cell BiologybioRxiv
LncRNA Dnmt3aos regulates Dnmt3a expression leading to aberrant DNA methylation in macrophage polarization
X. Li, Y. Zhang, M. Zhang…·K. Lv
The paper identifies Dnmt3aos as a lncRNA regulating Dnmt3a expression and DNA methylation in macrophage polarization, revealing its role in modulating IFN-gamma expression.
DOI 10.1096/fj.201902379r - MicrobiologybioRxiv
A 3-hydroxy-3-methylglutaryl-CoA synthase-based probe for the discovery of the acyltransferase-less type I polyketide synthases
H. Liang, L. Jiang, Q. Jiang…·Y. Huang
The paper identifies HCSs associated with AT-less type I PKSs through genome mining and reveals their diversity across strains and soil samples.
DOI 10.1111/1462-2920.14787 - MicrobiologybioRxiv
Adding function to the genome of African Salmonella ST313
R. Canals, D. L. Hammarlöf, C. Kröger…·J. Hinton
The paper compares genomic and transcriptomic differences between Salmonella ST313 and ST19 isolates to identify phenotypic variations and a novel plasmid maintenance system.
DOI 10.1371/journal.pbio.3000059 - MicrobiologybioRxiv
Microbial contamination screening and interpretation for biological laboratory environments
K. Ning, X. Li, X. Zhu, W. Wang
This study identifies and analyzes microbial contaminants in biological laboratories, finding that lab type influences microbial communities more than sampling site, and identifies environmental and human factors as key sources.
DOI 10.1016/j.medmic.2020.100021 - Cell BiologybioRxiv
Mother centrioles are dispensable for deuterosome formation and function during basal body amplification
H. Zhao, Q. Chen, Q. Huang…·X. Zhu
The paper shows that mother centrioles are not required for deuterosome formation and function during basal body amplification in multiciliate cells.
DOI 10.15252/embr.201846735 - BioengineeringbioRxiv
Probing the Acyl Carrier Protein-Enzyme Interactions within Terminal Alkyne Biosynthetic Machinery
The paper investigates ACP interactions with alkyne biosynthetic enzymes JamA and JamB, showing JamB has stronger ACP interaction and identifying key ACP residues critical for compatibility with JamB.
DOI 10.1002/aic.16355 - BiophysicsbioRxiv
Activity of Antimicrobial Peptides Decreases with Increased Cell Membrane Crossing Free Energy Cost
R. Zou, X. Zhu, Y. Tu…·M. P. Landry
This study shows that increased intermolecular interactions in antimicrobial peptides raise the energy cost to cross bacterial membranes, reducing their antibacterial activity.
DOI 10.1021/acs.biochem.8b00052 - BiophysicsbioRxiv
Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half assembled intermediate
D. Zhou, X. Zhu, S. Zheng…·K. Ye
The paper reports the cryo-EM structure of an early pre-60S ribosome intermediate, revealing a half-assembled subunit and key assembly factors involved in rRNA domain joining.
DOI 10.1007/s13238-018-0526-7 - PhysiologybioRxiv
TRIF is a key inflammatory mediator of acute sickness behavior and cancer cachexia
K. G. Burfeind, X. Zhu, P. R. Levasseur…·D. L. Marks
This study shows TRIF is crucial for inflammation-driven sickness behavior and cancer cachexia, with TRIFKO mice showing reduced symptoms and inflammatory markers.
DOI 10.1016/j.bbi.2018.05.021