Y. Yu

The paper shows that ATPase binding at one end of the 20S proteasome allosterically opens the opposite gate, promoting symmetric and asymmetric proteasome configurations.

This study shows that transient exposure to miR-203 enhances the differentiation capacity of murine and human PSCs by reversing DNA methylation.

This study compares empathic responses in male and female mice and rats, finding no species difference in empathic behaviors but notable sex differences in mice.

This paper describes an RNA-based system to study HBV replication and predict drug resistance mutations.

This paper develops a network-based method to identify reproducible radiomic features across different imaging settings and validates it using phantom and external datasets.

This study evaluates two tDCS optimization schemes for single and multi-target brain stimulation, showing that parameter settings significantly affect outcomes, especially in multi-target cases, and proposes improved weighted schemes.

This study shows TRIM21 and PHLDA3 regulate cross-talk between PI3K/AKT signaling and PPP metabolism, with implications for cancer therapy.

This study shows that Coxiella burnetii phase II can grow under normoxic conditions in ACCM-2 with tryptophan, and its transformant grows robustly without tryptophan, suggesting tryptophan and a temperature-sensitive signal are involved in normoxic growth.

This study examines how shift-work affects carotid artery health and cerebral blood flow in SHR and WKY rats, finding increased blood pressure, arterial thickening, and reduced blood flow.

This study identifies B7-H4 as a potential therapeutic target in bladder cancer, showing that anti-B7-H4 antibodies enhance immune responses and reduce tumor size in preclinical models.

The paper uses MD simulations to study ligand transport by P-gp and shows lipids also play a role in this process.

This study identifies a chitinase gene from Chinese wildrye that enhances pathogen resistance and saline-alkali stress tolerance in transgenic tobacco and maize without affecting growth.

The study examines microbial dynamics and host interactions in urethral catheter biofilms, showing antibiotic treatments alter composition but fail to eliminate biofilms.

The paper reports the crystal structure and cryo-EM reconstruction of a constitutively active Drosophila Orai mutant, revealing the molecular mechanism of channel activation and Ca2+ permeation.

The paper uses Structure-seq to analyze RNA structure changes in Arabidopsis shoots and roots under salt stress, finding tissue-specific structural and abundance correlations.

This study shows Defensin, an antimicrobial peptide, works with Tumour Necrosis Factor to kill tumour cells in Drosophila, demonstrating an in vivo anti-cancer role for an endogenous AMP.

The paper identifies StPOPA, an anionic peroxidase in potato, and shows its role in enhancing resistance against Phytophthora infestans by promoting callose and ROS accumulation.

This study investigates nasal immune responses in rainbow trout to Ichthyophthirius multifiliis infection, finding parasite-specific IgT production and B-cell proliferation in the nasal mucosa.

The paper shows that miR1510 in Phaseoleae species is primarily a 22 nt isoform due to monouridylation, and demonstrates how post-processing modifications can optimize miRNA function.

The paper identifies a new susceptibility gene in rice by analyzing TAL effector repertoires and their functional roles in bacterial leaf blight.

This paper introduces a Bayesian method for inferring phylogenetic networks from bi-allelic markers, demonstrating good accuracy and robustness on simulated and empirical data.

The paper analyzes urinary tract infection samples using 16S rDNA and whole genome shotgun sequencing to compare microbial diversity and identify pathogens missed by conventional methods.

This study shows that Orai1-mediated Ca2+ signals regulate basal T cell motility by reducing pauses during migration, enhancing cell velocity in confined spaces.

This study introduces iMAAPs, a method to infer multiple-wave population admixture by modeling ALD decay with polynomial functions, showing improved performance over existing methods.