Caroline Hayward

The paper identifies genetic loci associated with email contact and mental health survey participation in two cohorts, finding genetic correlations with education, health, and psychological distress.

This study investigates genetic associations between major depression and cardio-metabolic traits, finding shared genetic aetiology regardless of depression onset age.

This study identifies 29 differentially methylated sites associated with respiratory function and COPD, showing improved prediction of COPD risk when added to clinical models.

This study identifies 11 genome-wide significant loci for retinal detachment by combining small clinical and large population-based datasets, with six loci replicated in an independent dataset.

This study identifies X chromosome variants associated with neuroticism using UK Biobank data, finding 204 significant markers and estimating X-variant heritability at 0.34%.

The paper identifies 279 new genetic signals for lung function across multiple ancestries, showing associations with COPD and pleiotropic effects.

This study performs genome-wide association studies and genome-wide by environment interaction studies of depressive symptoms and stress in UK Biobank and Generation Scotland, identifying genetic and gene-environment interactions associated with depression.

The paper identifies 9 novel genetic loci, including low-frequency variants in TP53, associated with head circumference and intracranial volume in up to 46,000 individuals.

This study validates the diathesis-stress model for depression by showing gene-environment interaction effects, particularly in women, using data from Generation Scotland.

This study identifies a genetic variant associated with stress-sensitivity and shows it improves prediction of major depressive disorder using polygenic risk scores.

This study conducts a trans-ancestral GWAS of alcohol dependence, identifying genetic variants and correlations with psychiatric disorders.

This study identifies 46 novel genetic loci associated with alcohol consumption and suggests shared genetic mechanisms with neuropsychiatric disorders using GWAS and functional analyses.

This paper conducts a genome-wide meta-analysis of chronic back pain in 158,025 individuals, identifying three genetic loci associated with the condition.

This paper identifies genetic loci associated with retinal vascular tortuosity and links one of them to coronary artery disease risk.

This study identifies 99 genetic loci associated with general cognitive function using data from 280,360 individuals, finding genes linked to brain structure and neurodegenerative disorders.

The paper investigates the genetic and environmental contributions to stressful life events and their overlap with depression and neuroticism using a large family-based sample.

The paper uses family data to estimate genetic effects on intelligence and personality, finding that rare variants explain more variance than previously reported using unrelated individuals.

This study performs genome-wide meta-analyses of depression in two large cohorts, finding one significant locus and suggesting larger sample sizes may be more informative than phenotypic stratification.

This study performs a genome-wide haplotype-based association analysis for major depressive disorder using two cohorts, identifying significant haplotypes potentially linked to the disorder.

The paper demonstrates the research value of linking Electronic Health Records to genetic data in Generation Scotland participants and describes access mechanisms.

This study investigates shared genetic architecture between subcortical brain volumes and MDD using GWAS data from multiple cohorts, finding a non-significant positive genetic correlation for hippocampal volume.

This study conducts a GWAS of alcohol consumption in UK Biobank, identifying 8 loci, including novel associations, and reports genetic overlaps with schizophrenia, HDL cholesterol, smoking, and anthropometric traits.

This study identifies shared genetic and couple-associated environmental factors contributing to both clinical and self-declared depression risks.

This study investigates the interaction between polygenic risk scores for schizophrenia and major depressive disorder (MDD) in two cohorts, finding reduced case-control differences in distress and neuroticism with higher schizophrenia risk.

This study quantifies index event bias in large genetic association studies and finds it can explain some associations between disease risk alleles and BMI.

This study identifies 50 novel schizophrenia GWAS loci and shows common risk variants are enriched in mutation-intolerant genes maintained by background selection.

This study identifies 9 new genetic loci associated with neuroticism using genome-wide data from over 106,000 individuals.

This study identifies genetic and environmental factors contributing to chronic pain and its link to major depressive disorder using data from Generation Scotland and UK Biobank.