Attention Deficit Hyperactivity Disorder

Susceptibility to Task-irrelevant Auditory Distractors in Relation to Visual Working Memory in Children With and Without ADHD

This study examines how susceptibility to auditory distractors relates to visual working memory in children with and without ADHD, finding distinct patterns between groups.

DUSP6 loss enhances dopamine secretion and modulate neurodevelopment in ADHD iPSC-derived dopaminergic neurons

This study investigates the role of DUSP6 in ADHD by generating DUSP6 knockouts in iPSC-derived dopaminergic neurons, finding increased dopamine secretion and transcriptomic changes linked to neurodevelopment and psychiatric disorders.

Detrimental effects of atomoxetine on visual signal detection in rats: Comparison with ADHD psychomotor stimulant drugs

This study compares the effects of atomoxetine and ADHD stimulants on visual attention in rats, finding atomoxetine impairs attention while stimulants have variable effects.

Effects of mind-wandering on cognitive and neural processes: Identifying specific impairments in adults with attention-deficit/hyperactivity disorder

This study examines how mind-wandering affects cognitive and neural processes in adults with ADHD, finding specific impairments in performance monitoring.

Working memory deficits and altered prefrontal/hippocampal activation in p35 knockout mice with ADHD-like phenotypes: influence of sex and acute monoaminergic treatments

The paper investigates working memory deficits and prefrontal/hippocampal activation in p35 knockout mice with ADHD-like phenotypes, showing sex and pharmacological treatment effects.

Developmental Differences in White Matter Microarchitecture in Youth with ADHD: Longitudinal Findings from the ABCD Study

This study examines how ADHD affects white matter microarchitecture in youth over time using diffusion MRI and finds reduced isotropic diffusion in ADHD individuals.

Novel Dopamine 4 Receptor Ligands Differentially Ameliorate ADHD-like Behaviors in Spontaneously Hypertensive Rats

This study evaluates two novel D4R ligands in ADHD models, showing differential effects on ADHD-like behaviors with minimal impact on controls.

ADHD and intelligence polygenic scores associations with developmental dimensions in children with attention, learning and memory difficulties

The paper examines associations between ADHD and intelligence polygenic scores and developmental dimensions in children with attention, learning, and memory difficulties, finding significant links with cognitive and behavioral traits.

ADHD Medications and Preadolescent Brain Structure: Patterns of Cortical Attenuation from the ABCD Study

The paper uses the ABCD Study to analyze how ADHD medications affect cortical structure, finding that stimulants reduce ADHD-related cortical changes.

ADHD-like traits reshape the balance between inhibitory control and predictive processes

This study investigates how ADHD-like traits affect the interaction between response inhibition and statistical learning in a non-clinical sample.

Sleep-like Slow Waves During Wakefulness Mediate Attention and Vigilance Difficulties in Adult Attention-Deficit/Hyperactivity Disorder

This study finds that increased sleep-like slow wave (SW) density during wakefulness in ADHD is associated with attentional difficulties, suggesting a mechanistic link between sleep disturbances and attentional issues.

Rate dependent Effects of AMPH on attentional processes as measured by 5C-CPT task

This study investigates the rate-dependent effects of amphetamine on attentional performance in rats using the 5C-CPT task, finding both direct and inverse relationships between baseline performance and drug-induced changes.

Stimulant medications affect arousal and reward, not attention

This study shows stimulant medications affect brain connectivity in action/motor and reward-related regions, not attention networks, and mimic the effects of sleep.

Cell type-specific methylome-wide association studies of childhood ADHD symptoms

This study identifies cell type-specific DNA methylation associations with childhood ADHD symptoms using deconvolution and sequencing-based methylation data from peripheral and cord blood.

Limbic System White Matter in Children and Adolescents with ADHD: A Longitudinal Diffusion MRI Analysis

This study uses diffusion MRI to examine limbic system white matter development in children and adolescents with ADHD, finding reduced microstructural organization and connectivity linked to symptom severity.

Improving Machine Learning Prediction of ADHD Using Gene Set Polygenic Risk Scores and Risk Scores from Genetically Correlated Phenotypes

Expression profile of the ADHD risk gene ADGRL3 during human neurodevelopment and the effects of genetic variation

This study investigates ADGRL3 expression during human neurodevelopment and finds that the rs1397547 SNP is associated with increased ADGRL3 transcription and a unique transcriptional profile in cortical neurons.

Common and rare variant analyses implicate late-infancy cerebellar development and immune genes in ADHD

This study identifies common and rare variant risk loci for ADHD in a Hong Kong population, implicating cerebellar development and immune genes.

White matter properties in fronto-parietal tracts predict maladaptive functional activation and deficient response inhibition in ADHD

The paper investigates white matter properties in fronto-parietal tracts and their association with response inhibition deficits in ADHD using diffusion data and a Go/No-go task.

Selective attention and sensitivity to auditory disturbances in a virtually-real Classroom: Comparison of adults with and without AD(H)D

This study compares attention and distractibility in adults with and without AD(H)D using a virtual classroom, finding higher neural responses to irrelevant sounds and reduced speech tracking in AD(H)D individuals.

Reduced temporal and spatial stability of neural activity patterns predict cognitive control deficits in children with ADHD

This study identifies increased temporal variability and reduced spatial stability in neural activity patterns in children with ADHD, correlating with cognitive control deficits and symptom severity.

Neurophysiology of perceptual decision-making and its alterations in attention deficit hyperactivity disorder (ADHD)

This study uses EEG to analyze perceptual decision-making in ADHD, finding altered neural dynamics in attentional selection, sensory evidence accumulation, and response preparation compared to typically developing children.

Identifying Developmental Changes in Functional Brain Connectivity Associated with Cognitive Functioning in Children and Adolescents with ADHD

The paper uses machine learning on fMRI data to predict cognitive abilities in children and adolescents with ADHD, finding distinct neural mechanisms in different age groups.

Associations between attention-deficit hyperactivity disorder genetic liability and ICD-10 medical conditions in adults: Utilizing electronic health records in a Phenome-Wide Association Study

This study identifies 80 medical conditions associated with ADHD genetic liability in adults without ADHD diagnosis using EHR data.

Cortical gradient perturbation in attention deficit hyperactivity disorder correlates with neurotransmitter-, cell type-specific and chromosome- transcriptomic signatures

This study identifies cortical gradient perturbations in ADHD linked to neurotransmitter, cell type, and chromosome-specific transcriptomic signatures using neuroimaging and molecular data.

Reduced recruitment of inhibitory control regions in very young children with ADHD during a modified Kiddie Continuous Performance Task: a fMRI study.

This study uses fMRI to assess inhibitory control in young children with ADHD and typically developing peers using a modified K-CPT, revealing brain activity differences in inhibitory control regions.

Self-regulation of attention in children in a virtual classroom environment: a feasibility study

This study explores a non-pharmacological approach combining EEG neurofeedback and virtual reality to improve attention in children, showing promising engagement and preliminary improvements in attentional function.

Resting-state EEG dynamics help explain differences in response control in ADHD: Insight into electrophysiological mechanisms and sex differences

The paper examines how resting-state EEG dynamics relate to response control in ADHD, finding that oscillatory power, not phase-synchrony or modularity, is most associated with response control, and this link is stronger in ADHD and males.

Behavioral and Neuroanatomical Investigation of Attention Deficit Hyperactivity Disorder Pathogenesis in Juvenile Spontaneously Hypertensive Rats

This study investigates ADHD pathogenesis in juvenile SHR rats, finding normal mesocortical dopaminergic systems but increased locomotor activity, suggesting SHR may model hyperactive/impulsive ADHD subtype.

Atypical Biological Motion Perception in Children with Attention Deficit Hyperactivity Disorder: Local Motion and Global Configuration Processing

This study investigates biological motion perception in children with ADHD, finding atypical processing of local and global cues and linking it to attention and intelligence.