Forensic and Genetic Research

Reconstruction of nine thousand years of agriculture-based diet and impact on human genetic diversity in Asia

The paper reconstructs 9000 years of agricultural diet in Asia and shows its impact on genetic variation in 29 Asian populations, identifying genes related to metabolism as targets of dietary-driven selection.

A likelihood method for estimating present-day human contamination in ancient DNA samples using low-depth haploid chromosome data

This paper introduces a likelihood method to estimate present-day human contamination in ancient DNA samples using low-depth haploid chromosome data, showing improved accuracy compared to existing methods.

Population genetic data of the 21 autosomal STRs included in GlobalFilerTM kit of a population sample from the Kingdom of Bahrain

The paper analyzes 21 autosomal STRs from 543 Bahraini males using the GlobalFiler kit to assess genetic diversity and forensic parameters, finding most loci in HWE and SE33 as the most polymorphic marker.

Inland-coastal bifurcation of southern East Asians revealed by Hmong-Mien genomic history

The paper analyzes genomic data from Hmong-Mien-speaking populations to reveal an inland-coastal genetic split linked to agricultural expansion in southern China.

Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome

The paper examines mtDNA heteroplasmy sharing between human liver lobes, finding higher sharing in the control region and suggesting selection influences this pattern.

The presence and impact of reference bias on population genomic studies of prehistoric human populations

This paper shows reference bias affects ancient DNA studies and suggests filtering strategies to reduce its impact on population genomic analyses.

Genetic evidence suggests relationship between contemporary Bulgarian population and Iron Age steppe dwellers from Pontic-Caspian steppe.

The paper investigates the genetic relationship between contemporary Bulgarians and Iron Age steppe dwellers from the Pontic-Caspian steppe, identifying a Caucasian genetic component introduced through migration.

Runs of Homozygosity in sub-Saharan African populations provide insights into a complex demographic and health history

This study analyzes runs of homozygosity in sub-Saharan African populations to uncover demographic history and health-related genetic variation.

Quasi-Mendelian Paternal Inheritance of mitochondrial DNA: A notorious artifact, or anticipated mtDNA behavior?

The paper challenges previous interpretations of biparental mtDNA inheritance, proposing a model where paternal mtDNA undergoes selective fixation due to initial low copy number and a selective advantage.

Temporal changes in genetic admixture are linked to heterozygosity and health diagnoses in humans

The paper examines how changes in genetic admixture over time affect heterozygosity and health outcomes in a southeastern U.S. population.

Consequences of PCA graphs, SNP codings, and PCA variants for elucidating population structure

The paper evaluates common misuses of PCA in SNP data analysis and recommends best practices for improving population structure elucidation.

Genetic admixture patterns in Argentinian Patagonia

This study analyzes genetic admixture in Argentinian Patagonia using 46 ancestry informative markers, revealing regional variations in Native American, European, and African ancestry contributions.

Models of archaic admixture and recent history from two-locus statistics

The paper develops a likelihood-based framework to infer demographic history using two-locus statistics, showing that models including archaic admixture better explain genetic diversity patterns.

The population history of northeastern Siberia since the Pleistocene

This paper analyzes ancient genomes from northeastern Siberia to reveal complex population migrations and admixture events over the past 40,000 years.

New kinship and FST estimates reveal higher levels of differentiation in the global human population

The paper introduces new kinship and FST estimators, showing higher genetic differentiation in global human populations compared to existing methods.

Fine-scale Inference of Ancestry Segments without Prior Knowledge of Admixing Groups

This paper introduces an algorithm to infer ancestry segments and admixture events without prior knowledge of mixing groups, showing improved accuracy over existing methods.

A likelihood-free estimator of population structure bridging admixture models and principal components analysis

ALStructure estimates population structure using a likelihood-free method that combines principal components analysis with admixture model constraints, outperforming existing methods in accuracy and speed.

The Genetic Chain Rule for Probabilistic Kinship Estimation

This paper introduces a method for kinship estimation using large SNP panels, resolving parent-sibling relationships and distinguishing degrees of kinship.

Assortative mating on ancestry-variant traits in admixed Latin American populations

The paper identifies phenotypic cues and genetic architecture underlying ancestry-based assortative mating in admixed Latin American populations using genome-wide haplotype analysis.

The Sibship Index can’t discriminates Half-Sibs from Full-Sibs; a new algorithm, including maternal genotype, can do it

The paper shows the current Sibship Index fails to distinguish full-sibs from half-sibs and proposes a corrected index using maternal genotype to improve accuracy.

Contrasting paternal and maternal genetic histories of Thai and Lao populations

The paper analyzes paternal and maternal genetic histories of Thai and Lao populations, finding contrasting patterns of male and female genetic variation and demographic expansions.

The Arrival of Steppe and Iranian Related Ancestry in the Islands of the Western Mediterranean

The paper analyzes ancient DNA from the Balearic Islands, Sicily, and Sardinia to trace the arrival and spread of Steppe and Iranian-related ancestries in the western Mediterranean, revealing complex admixture histories.

Population history from the Neolithic to present on the Mediterranean island of Sardinia: An ancient DNA perspective

This study uses ancient DNA to trace Sardinia's population history from the Neolithic to the present, finding genetic continuity and limited Bronze Age Steppe ancestry.

Mitogenomes illuminate the origin and migration patterns of the indigenous people of the Canary Islands

The paper analyzes ancient mitogenomes from the Canary Islands to trace the origin and migration patterns of indigenous populations, identifying new lineages and supporting a model of two distinct migrations.

Positive selection in Europeans and East-Asians at the ABCA12 gene

The paper confirms a positive selection signal at the ABCA12 gene in Europeans and East-Asians and refines its genomic location, finding no direct effect on gene expression but tracing the T allele's trajectory in human history.

Late Pleistocene human genome suggests a local origin for the first farmers of central Anatolia

The paper analyzes ancient genomes from Anatolia to show genetic continuity between hunter-gatherers and early farmers, suggesting limited migration in the origin of farming in central Anatolia.

Jomon genome sheds light on East Asian population history

The paper analyzes the genome of a Jomon individual to infer migration patterns into East Asia, finding multiple waves and a coastal route from Southeast Asia.

Optimisation of rapid STR analysis using a standard DNA forensic pipeline

This study optimizes a DNA forensic pipeline by modifying PCR and CE protocols to reduce STR analysis time for buccal cell samples from 97-102 to under 80 minutes.

SNP Identity Searching Across Ethnicities, Kinship, and Admixture

The paper presents models for SNP-based identification and mixture analysis across ethnicities, kinship, and admixture using in silico datasets.

Probabilistic ancestry maps: a method to assess and visualize population substructures in genetics

This paper introduces GTM for ancestry classification and visualization, showing it can better capture ancestry substructures than PCA by estimating class probabilities and explaining more variance.