Olfactory and Sensory Function Studies

Odorant representations indicate nonlinear processing across the olfactory system

The paper shows that odorant identity is encoded through nonlinear interactions in the olfactory system of rainbow trout, as revealed by information-theoretic metrics in LFPs.

Structure-Function Mapping of Olfactory Bulb Circuits with Synchrotron X-ray Nanotomography

The paper uses synchrotron X-ray nanotomography to link subcellular anatomy to odor response diversity in mouse olfactory bulb projection neurons.

Evidence of elemental encoding at the olfactory periphery

The paper investigates how odor qualities are encoded by the olfactory system, showing that potent agonists share perceptual qualities through distinct layers and combinatorial receptor activation.

The Aquaporin-4 expression and localization in the olfactory epithelium modulate the odorant-evoked responses and olfactory driven behavior

This study investigates the role of AQP4 isoforms in the olfactory epithelium, showing their impact on cell density, odorant responses, and olfactory behavior in knockout mice.

Muscone-specific olfactory protein reveals the putative scent-marking pheromone in the Sunda pangolin (Manis javanica)

This study identifies muscone as a potential male-specific scent-marking pheromone in Sunda pangolins through functional expression of odorant-binding proteins and behavioral assays.

Amplification of olfactory transduction currents implements sparse stimulus encoding

This study shows that TMEM16B reduces sensory representation density in OSNs, enhancing sparsity and improving olfactory-guided behaviors.

Shapley Fields Reveal Chemotopic Organization in the Mouse Olfactory Bulb Across Diverse Chemical Feature Sets

The paper introduces Shapley fields to analyze chemotopic organization in the mouse olfactory bulb and finds weak spatial organization of chemical feature sensitivity across diverse feature sets.

3D spatial transcriptomics reveals the molecular structure of input and output pathways in the mouse olfactory bulb

The paper uses 3D spatial transcriptomics to map the molecular organization of the mouse olfactory bulb, revealing symmetric glomeruli and asymmetric deeper layer cells.

Elusive scents: neurocomputational mechanisms of verbal omissions in free odor naming

The paper proposes a computational model to explain odor naming omissions by linking Bayesian-Hebbian learning to linguistic ambiguity in odor-label associations.

Local olfactory nerve stimulation triggers patchy activation of columns across rat olfactory bulb

The paper provides direct evidence for functional columnar organization in the rat olfactory bulb using activity-dependent labeling and tissue clearing.

MITF regulates gene expression in middle tufted neurons and other projection neurons of the olfactory bulb

The paper identifies MITF target genes in olfactory bulb projection neurons, revealing their role in regulating neuronal activity and middle tufted cell function.

Synergistic olfactory nerve input and cholinergic neuromodulation can activate ERK in rat olfactory bulb vasopressin cells

An evolutionarily conserved scheme for reformatting odor concentration in early olfactory circuits

The paper identifies an evolutionarily conserved mechanism in olfactory circuits that preserves odor concentration information through diverse second-order neuron responses, despite flat population-level averages.

Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal reward contingency signals during rule-reversal

This study shows that piriform cortex feedback to the olfactory bulb carries reward contingency signals and rapidly adapts during rule-reversal tasks in mice.

Anatomy, histology and ultrastructure of the adult human olfactory peduncle: blood vessel and corpora amylacea assessment

This study examines the anatomy, histology, and ultrastructure of the human olfactory peduncle using microscopy techniques, revealing three layers, neuronal types, and associations between corpora amylacea and astrocytes.

Challenges in inferring breathing rhythms from olfactory bulb local field potentials

This study investigates the ability to infer respiratory timing and frequency from olfactory bulb local field potentials, finding that while LFPs align with respiratory cycles, precise event recovery is challenging due to variable delays.

Odor-evoked respiratory responses throughout development in sighted and blind mice

This study assesses odor-evoked respiratory responses in congenitally blind and sighted mice across developmental stages to evaluate olfactory function and plasticity.

Paired and solitary ionocytes in the zebrafish olfactory epithelium

The paper characterizes ionocyte subtypes in zebrafish olfactory epithelium, identifying three types with distinct functions and distributions.

Recent odor experience selectively modulates olfactory sensitivity across the glomerular output in the mouse olfactory bulb

The paper shows that recent odor experiences selectively modulate olfactory sensitivity in specific glomeruli of the mouse olfactory bulb for up to 30 seconds.

Sex differences in olfactory behavior and neurophysiology in Long Evans Rats

This study examines sex differences in olfactory behavior and neurophysiology in Long Evans rats, finding females sample odors shorter and have lower neural oscillation power, with no estrus-related variance differences.

Projection neurons are necessary for the maintenance of the mouse olfactory circuit.

This study shows that projection neurons are necessary for maintaining the stability of the adult mouse olfactory circuit, as their removal leads to structural changes in the olfactory bulb despite preserved odor detection.

Perceptual constancy for an odour is acquired through changes in primary sensory neurons

The paper shows that perceptual constancy for odors in mice develops through changes in olfactory receptor neuron sensitivity, enabling stable odor recognition despite concentration variations.

Structural regeneration and functional recovery of the olfactory system of zebrafish following brain injury

This study investigates olfactory system regeneration in zebrafish after excitotoxic injury, showing full functional recovery through tissue remodeling and neurogenesis.

Lateral entorhinal cortex afferents reconfigure the activity in piriform cortex circuits

This study investigates how lateral entorhinal cortex (LEC) afferents modulate piriform cortex (PCx) activity by reconfiguring excitatory and inhibitory circuits in response to olfactory and spatial contextual inputs.

Lack of Ameliorative Effect of Chronic Oral Nicotine on Olfactory Dysfunction in Young Adult Presenilin-1/2 Double Knockout Mice of a Dementia Model

This study shows that chronic nicotine does not improve olfactory dysfunction in young adult Presenilin-1/2 double knockout mice, which model dementia, and highlights age-related decline in olfactory function.

Olfactory bulb tracks breathing rhythms and place in freely behaving mice

The paper shows that the mouse olfactory bulb tracks breathing rhythms and self-location, providing contextual information for olfactory processing.

Spatiotemporal regulation by downstream genes of Prok2 in olfactory system: from development to function

This study investigates the role of Prok2 in olfactory system development and function using Prok2 knockout mice, showing disrupted olfactory sensory neuron maturation and glomerulus formation leading to olfactory dysfunction.

Communication subspace dynamics of the canonical olfactory pathway

The paper identifies a communication subspace in the olfactory pathway that enables feedforward and feedback transmission during nasal respiration.

A Protocol for Neuralized Murine Olfactory Organoids

This paper presents a method to generate olfactory organoids from adult mice to study environmental interactions with the olfactory epithelium and disease processes.

The role of dopaminergic, cholinergic and noradrenergic networks in hyposmia in Parkinson's disease

This study investigates network alterations in olfactory dysfunction in Parkinson's disease and iRBD patients using multimodal MRI, finding correlations between olfactory function and specific brain regions and networks.