Elasticity and Material Modeling

Haemodynamic impact of implant materials and anastomotic angle in peripheral vascular grafts

This study uses fluid-structure interaction simulations to evaluate how graft material, suture material, and anastomosis angle affect blood flow and shear stress in vascular grafts.

Capturing sclera anisotropy using direct collagen fiber models. Linking microstructure to macroscopic mechanical properties.

This study uses direct fiber modeling to capture specimen-specific 3D collagen fiber architecture and anisotropic mechanics of sclera samples under various loadings.

Statistical Atlas-Based Surrogate Model of Biventricular Wall Mechanics

The paper develops a surrogate model for ventricular wall mechanics using a statistical atlas and finite element simulations, achieving high accuracy in predicting displacements.

Linking arterial biomechanics, contractility, and microstructure: A novel platform for combined structure-function assessment in murine arteries under physiological conditions

This paper develops a dynamic biaxial pressure myograph with two-photon microscopy to study arterial biomechanics and microstructure under physiological conditions in mice.

A reference model for adult human cardiovascular mechanics

The paper calibrates a cardiovascular mechanics model using clinical hemodynamic data to create a reference model for theoretical studies.

Along- and cross-muscle fiber shear moduli in skeletal muscle

This study measures shear moduli of skeletal muscle along and across muscle fibers in rats, finding no significant difference but greater anisotropy at higher strains.

Bruch's Membrane Contributes to the Structural Integrity of the Human Eye

This study investigates the structural contribution of Bruch's membrane and sclera to the ocular wall by comparing their biomechanical properties under tension.

An Anisotropic Reactive Viscoelastic Model of the Rhesus Macaque Cervix for Studying Cervical Remodeling

This study develops an anisotropic reactive viscoelastic model of the rhesus macaque cervix to understand its time-dependent remodeling during pregnancy and its implications for preterm birth.

Community Challenge towards Consensus on Characterization of Biological Tissue: C4Bio's First Findings

This study assesses inter-laboratory variability in mechanical property characterization of porcine aorta through two testing rounds, highlighting persistent discrepancies despite protocol standardization.

Stretching the Limits: From Planar-Biaxial Stress-Stretch to Arterial Pressure-Diameter

This study translates lab-based arterial stress-stretch data into clinically relevant pressure-diameter predictions using a fiber-reinforced model and systematic validation.

Personalized Multiscale Modeling of Left Atrial Mechanics and Blood Flow

This paper develops a personalized multiscale model of left atrial mechanics and blood flow to simulate deformation and hemodynamics using patient-specific data.

The Effects of DMSO Cryopreservation on the Biomechanics and Histology of Human Cerebrovascular Tissue

This paper evaluates the effects of DMSO cryopreservation on human cerebrovascular tissue biomechanics and histology, finding it fails to consistently protect tissue integrity and increases elastin fractures.

Methods for Quantitative Analyses of Nerve Fiber Deformation in the Myenteric Plexus Under Loading of Mouse Distal Colon and Rectum

The paper develops methods to mechanically test and analyze nerve fiber deformation in the myenteric plexus of mouse colorectum under loading, providing tools for quantitative stretch ratio calculations.

Fluid-structure Interaction Simulation of the Cerebrovascular Circulation: Immersed Boundary versus Arbitrary Lagrangian Eulerian Mesh Formulations

This study compares immersed boundary and arbitrary Lagrangian Eulerian methods for simulating cerebrovascular fluid-structure interactions, finding that ALE provides more accurate stress and strain measurements in smaller vessels.

A Novel Method for the Mechanical Testing of Human Cerebrovascular Tissue: A Validation Study

This study validates a novel mechanical testing device for human cerebrovascular tissue, showing it can accurately measure viscoelastic properties and predict vessel wall behavior.

Discovering dispersion: How robust is automated model discovery for human myocardial tissue?

This study evaluates the robustness of automated model discovery in human myocardial tissue by incorporating generalized structure tensors to account for fiber dispersion.

Time-Dependent Material Properties and Composition of the Nonhuman Primate Uterine Layers Through Gestation

This study characterizes the structural, compositional, and time-dependent micro-mechanical properties of nonhuman primate uterine layers across gestation and compares them to human data.

Low ultimate tensile strain in atherosclerotic plaques is linked to the presence of neovascularisation: insights from ex vivo uniaxial tensile testing

This study links neovascularisation in atherosclerotic plaques to lower ultimate tensile strain, suggesting mechanical instability and increased rupture risk.

Measurement of residual stress in the brain

The paper measures residual stress in brain tissue using MRI and finite element simulations, finding compressive stresses in grey matter and anisotropic tensile stresses in white matter aligned with axon orientation.

Nonlinear continuum description of the E. coli cell wall under high turgor pressure

The paper develops a continuum elastic model of E. coli peptidoglycan to study stress-strain relationships under large deformations and high turgor pressure.

Material Properties Of The Embryonic Small Intestine During Buckling Morphogenesis

The paper investigates the mechanical properties of the embryonic small intestine during development, identifying elastic fibers as key to its bending stiffness and mechanical anisotropy.

Development of an Open-source Low-cost Pressure Myography and Cardiac Flow Simulator, HemoLens, for Mechanical Characterization of Native and Engineered Blood Vessels

The paper develops HemoLens, a low-cost open-source pressure myography system for characterizing vascular mechanics in native and engineered blood vessels.

Arterial arcades and collaterals regress under hemodynamics-based diameteradaptation: a computational and mathematical analysis

The paper shows that arterial loops regress under hemodynamics-based diameter adaptation in computational and mathematical models.

Stress-free state in human carotid arteries cannot be revealed without layer separation

This study shows that residual stresses in human carotid artery layers are not fully released by a radial cut and require layer separation to reveal the stress-free state.

Biomechanical and Compositional Changes in the Murine Uterus with Age

This study examines age-related changes in murine uterine biomechanics and composition using Raman spectroscopy and biaxial inflation testing, finding decreased moduli with aging and increased elastin/collagen in the oldest group.

Measurement force, speed and post-mortem time affect the ratio of CNS grey to white matter elasticity

This study investigates how measurement force, speed, post-mortem time, and temperature affect the grey-to-white-matter elasticity ratio in spinal cord tissue, identifying parameter-dependent variations.

Constitutive neural networks for main pulmonary arteries: Discovering the undiscovered

Constitutive artificial neural networks trained on biaxial tests of 8 ovine main pulmonary artery samples consistently discover a two-term model: exponential first-invariant plus quadratic fifth-invariant terms.

Evolving properties of biological materials captured via needle-based cavity expansion method

This study uses VCCE to measure time-dependent mechanical changes in liver and gelatin, showing stiffening with age and demonstrating VCCE's precision in capturing these variations.

A Computational Framework to Optimize the Mechanical Behavior of Synthetic Vascular Grafts

This paper develops a computational framework to optimize vascular graft design by balancing compliance and buckling resistance through finite element analysis and optimization.

Finite element model of the non-keratinized buccal tissue under the impact of negative pressure

The paper develops a finite element model to simulate non-keratinized buccal tissue under negative pressure, validated through suction experiments and histological analysis.