Resilience to neuronal hyperactivity and restoration of the neuroimmune interactome by blocking fibrin-induced microglia activation in Alzheimers disease
Zhaoqi Yan, Andrew S. Mendiola, Kelli Lauderdale, Keun-Young Kim, Yu Yong, Kun Leng, Eric A. Bushong, Renaud Schuck, Anke Meyer‐Franke, Ayushi Agrawal, Michela Traglia, Natalie Gill, Reuben Thomas, Jonah N. Keller, Nikolaos Karvelas, , Katerina Akassoglou
This study shows that blocking fibrin-induced microglia activation reduces neuronal hyperactivity and restores the neuroimmune interactome in Alzheimer's disease.
bioRxiv · Jun 26, 2026 · PreprintNeuroscience