H. Zhao

This study evaluates simultaneous and sequential multi-species coronavirus mRNA vaccination, showing sequential vaccination induces stronger antibody responses against SARS-CoV-2, SARS-CoV, and MERS-CoV.

HSP90.6 regulates maize grain filling by affecting 26S proteasome-mediated nitrogen recycling and GF14-6-mediated carbon metabolism.

This study identifies the Toll pathway as a key antiviral defense in honey bees, with PGRP-S2 acting as a pattern recognition receptor that interacts with viral proteins to activate the pathway against IAPV infection.

This study shows that Mettl3-mediated m6A modification of Fgf16 limits cardiomyocyte proliferation and heart regeneration in mice.

The paper analyzes sequence and structural variability in the SARS-CoV-2 nucleocapsid protein, finding high mutability and structural plasticity linked to enhanced viral assembly efficiency.

This study identifies the EMC complex's role in regulating intestinal stem cell proliferation via the Hippo pathway in Drosophila, showing its negative regulation and evolutionary conservation.

This study identifies ACE2 as the receptor for NeoCoV and PDF-2180-CoV, two close MERS-CoV relatives in bats, showing they can use bat ACE2 and, with mutation, human ACE2.

This paper describes an oral protein cocktail, LMN-201, for C. difficile infection, showing it achieves high cure rates and validates spirulina as a delivery platform.

This study develops a metabolitin-based drug delivery system targeting GPR158 in glioblastoma, showing BBB penetration and anti-tumor effects in vitro and in vivo.

This study develops an intranasal vaccine against SARS-CoV-2 using an influenza virus vector and shows it provides rapid, prolonged, and broad protection against multiple variants in hamsters.

This study shows Senataxin and RNase H2 work together to remove R loops and prevent genome instability during class switch recombination.

This study shows that TFR1-mediated iron uptake in osteoclasts affects mitochondrial function and cytoskeleton, leading to increased bone mass in female mice.

The paper uses computational methods to predict miRNA-target regulatory modules in soybeans under abiotic stress and identifies stress-related modules with gene ontology enrichment.

The paper uses machine learning to predict DNA sequences that create strong optical responses to serotonin in DNA-carbon nanotube sensors, discovering five new sensors with improved performance.

This study constructs a ceRNA network in metastatic melanoma to identify prognostic markers and therapeutic targets, finding miR-3662 may be used in treatment.

ASER compiles sex reversal data from 18 species, including genes, regulatory networks, RNA-seq, and ISH images, to support research on animal breeding and human health.

This study shows vitamin D reduces mitochondrial ROS and oxidative phosphorylation while enhancing stress tolerance and anti-cancer responses in osteosarcoma cells.

This study shows that basic fibroblast growth factor (bFGF) undergoes liquid-liquid phase separation on the cell surface with heparan sulphate proteoglycans (HSPG), which is essential for downstream signaling.

The paper identifies a new lineage of largemouth bass in the Mobile-Tensaw Delta and shows complex introgression among three Micropterus lineages using SNP analysis and genetic screening.

The paper identifies an antibody that neutralizes all SARS-CoV-2 variants by targeting a conserved epitope on the spike protein.

The paper investigates how infant formula diets alter gut microbiome composition and short-chain fatty acid production, which may reduce food responsiveness and contribute to eating behaviors linked to obesity.

This paper develops a method to create 3D vascularized tissues using bioprinting and surgical anastomosis, showing improved viability and functionality in liver-like constructs.

This study investigates how SARS-CoV-2 N-protein interacts with nucleic acids to form supramolecular clusters and phase-separated droplets, revealing structural and energetic changes during assembly.

This study evaluates the effectiveness of Spray-Induced Gene Silencing (SIGS) by assessing RNA uptake efficiency in various eukaryotic microbes and its impact on plant disease control.

The paper identifies a reservoir of stem-like CD8 T cells in tumor-draining lymph nodes that sustain anti-tumor immunity by maintaining TCF1 expression and resisting terminal differentiation.

A single intranasal dose of ChAd-SARS-CoV-2-S vaccine protects against SARS-CoV-2 infection in rhesus macaques by inducing neutralizing antibodies and T cell responses.

This study uses human stem cells to show that HNF1A deficiency leads to impaired insulin secretion, altered insulin:C-peptide ratios, and abnormal secretory granules in beta-cells.

This study analyzes KSHV genome variability in Ugandan HIV-associated KS patients, finding high homogeneity within individuals but tumor-specific mutations and inactivations.

This study shows that TFH-B cell interactions driven by neoantigens enhance anti-tumor CD8+ T cell responses in lung adenocarcinoma.