P. Xu

This study shows that acetate metabolism in cumulus cells decreases with maternal age and correlates with oocyte maturity.

This study evaluates the diagnostic value of bronchoalveolar lavage fluid galactomannan (BALF GM) for pulmonary aspergillosis in chronic respiratory disease, finding an optimal cut-off value of 0.485 with high sensitivity and specificity.

This study shows that temporarily stopping CAR-T cell signaling can reverse exhaustion and improve their anti-tumor function through transcriptional and epigenetic changes.

This paper develops a high-throughput glycoproteomics method to measure site-specific polysialylation using LC-ESI-MS/MS after mild acid hydrolysis and desialylation.

This study identifies transcriptional changes in peanut seeds during dormancy release and germination, revealing key pathways and hormone-related genes involved in these processes.

This paper presents an analytical solution for a hybrid Logistic-Monod model that integrates nutrient limitation and growth inhibition, applicable to batch and CSTR cultures.

The paper corrects for artifactual post-harvest metabolism in subcellular isotope tracing to reveal compartment-specific metabolic kinetics.

This study identifies ERF109 as a regulator of auxin transport in Arabidopsis roots by directly controlling PIN2, PIN4, and PID, which are key components of auxin transport.

The paper identifies and characterizes odorant receptors in Culex quinquefasciatus and Aedes aegypti that respond to floral compounds, revealing their expression patterns and potential roles in mosquito behavior.

This paper optimizes violacein extraction and culture conditions in Yarrowia lipolytica to improve yield and purity, establishing a scalable production platform.

The paper tests a homemade clove-based mosquito repellent and finds it ineffective, while a higher concentration of eugenol shows moderate repellency, but DEET remains more effective and cheaper.

This study shows that overexpressing c-Jun in CAR-T cells reduces exhaustion and improves antitumor activity in vivo.

The paper investigates the membrane topology of RIFIN and STEVOR proteins in Plasmodium falciparum using N-linked glycosylation to determine their ER membrane insertion patterns.

This study identifies adaptable retromer structures and their role in cargo sorting from endosomes to the TGN or plasma membrane in mammals.

This study uses single-cell RNA-seq to analyze human infant retina, identifying cell types, communication networks, and developmental changes, providing a resource for retinal research and regenerative medicine.

This study uses single-cell RNA sequencing to analyze the cellular diversity and molecular markers in the retina of a trisomy 21 fetus, revealing communication networks and novel markers.

This paper engineers an acetyl-CoA metabolic shortcut in Yarrowia lipolytica to efficiently produce triacetic acid lactone from acetic acid, achieving a 8.5-fold increase in titer and 31.9% of theoretical yield.

This paper develops a method to simultaneously quantify and trace dNTP metabolites using isotope dilution and high-resolution mass spectrometry, showing improved accuracy and metabolic pathway insights.

The paper detects paclitaxel and its metabolites in meconium from newborns exposed to chemotherapy in utero, showing variability in fetal exposure levels.

This study shows that FADD is critical for intestinal intraepithelial lymphocyte (IEL) development, particularly affecting CD8αα+ TCRγδ+ T cells, and its loss worsens colitis.

This paper introduces Hessian-SMLM, a method to reduce pixel-dependent readout noise in sCMOS cameras for single-molecule localization microscopy, improving imaging time resolution.

The paper identifies an artefactual pyruvate formation from lactate during LC-MS analysis, highlighting the need for improved resolution or quantification in metabolomics studies.

The paper identifies two fragrance ingredients in Victoria’s Secret Bombshell and Ivanka Trump eaux de parfums that repel mosquitoes, but warns against using them as off-label repellents.

This study shows COPI mediates recycling of the SNARE Snc1 from early endosomes to the Golgi via recognition of a polyubiquitin sorting signal.