Runjia Cui

Spontaneous calcium transients in hair cell stereocilia

This study detects spontaneous calcium transients in hair cell stereocilia using fluorescent sensors and microscopy, showing they originate from mechanoelectrical transduction channels and occur in multiple stereocilia regions.

TMC1 and TMC2 are cholesterol-dependent scramblases that regulate membrane homeostasis in auditory hair cells

This study identifies TMC1 and TMC2 as cholesterol-dependent lipid scramblases that regulate membrane homeostasis in auditory hair cells, linking their dysfunction to hereditary deafness.

Transmembrane channel-like 4 and 5 proteins at microvillar tips are potential ion channels and lipid scramblases

The paper identifies TMC4 and TMC5 at microvillar tips and suggests they may function as ion channels and lipid scramblases, similar to mechanotransduction complexes in stereocilia.

Large-scale annotated dataset for cochlear hair cell detection and classification

The paper presents a large annotated dataset of cochlear hair cells for machine learning applications in hearing research.

LMO7 deficiency reveals the significance of the cuticular plate for hearing function

This study identifies LMO7 as a hair cell protein localized to the cuticular plate, showing that its deficiency leads to structural defects and progressive hearing loss.