X. Li

The paper shows that Clp protease and AscarD regulate CarD levels to help mycobacteria survive starvation by reducing rRNA synthesis.

This study evaluates antibiotic concentrations affecting gut bacteria and Ectropis obliqua growth, finding 300g/ml effectively clears bacteria without harming growth.

This study introduces three new tract-related strain measures to improve concussion prediction in finite element head models by analyzing white matter deformation during impacts.

This paper introduces a framework for generating personalized lifespan and pathological brain models by morphing a baseline model using multimodal imaging and mesh grouping, demonstrating its effectiveness across a diverse age and condition range.

The paper investigates off-target mutations caused by prime editors and finds no observable gRNA-independent off-target effects in transfected human cells.

This paper shows that palmitic acid induces autophagy in NAFLD neutrophils, leading to granule degradation and reduced adhesion, impairing neutrophil function.

The paper presents cryo-EM structures of the human calcium-sensing receptor in inactive and active states, revealing structural changes during activation.

This study shows that both increased and decreased SUMOylation enhance drought tolerance in apple by modulating MdDREB2A stability through SUMOylation and ubiquitination.

This study uses fMOST and scRNA-seq to map the spatial and cellular distribution of rabies virus in the mouse brain, revealing infection in multiple nuclei and non-neuronal cells.

This study identifies circMRPS35 as a factor promoting HCC progression and cisplatin resistance through miR-148a-3p sponging and a drug-induced peptide.

The paper identifies a novel IRES in WYMV RNA2 with variable eIF4E-binding sites and synergistic effects that enhance IRES activity.

The paper constructs phylogenetic trees using 8-mer motif sets from genome sequences, finding that CG and TA independent selection patterns reflect different evolutionary states in primates and insects.

This study identifies RasGRP1 as a bifunctional regulator that promotes acute inflammation and inhibits inflammation-associated cancer growth.

This study evaluates antibody resistance and ACE2 usage in SARS-CoV-2 variants, finding SA501Y.V2 shows the highest resistance and expanded host range.

This paper presents a hardware-software solution for co-registering photoacoustic tomography and MRI images in vivo, demonstrating hybrid-contrast imaging of tumor microenvironments.

This paper designs a low-cost smart glove for hand exercise in stroke rehabilitation, which can capture motion data and transfer it to an application.

This study shows YAP1 promotes breast cancer metastasis by enhancing TIAM1 expression through its enhancer, leading to increased RAC1 activity and invadopodia formation.

This study evaluates S-Trimer, a subunit vaccine candidate for COVID-19, showing it induces protective immunity in nonhuman primates with adjuvants.

This study identifies how coronavirus Nsp5 protein inhibits pyroptosis by cleaving GSDMD, preventing pore formation and viral replication inhibition.

The paper studies bacterial group migration and finds that spatially modulated individual behaviors enable coherent collective movement without complex computation.

The paper characterizes intraocular leukocyte infiltration in HLA-B27-associated uveitis using scRNA-seq, flow cytometry, and proteomics, revealing a unique dendritic cell infiltration pattern.

The paper introduces a microfluidic platform for high-throughput, dosage-controlled intracellular delivery of large cargos with high viability and efficiency.

This paper identifies interfacial compatibility conflict as the cause of poor dentin bonding durability and shows that hydrophobizing the demineralized dentin matrix enhances adhesive infiltration and bonding strength.

This paper develops a mucosal RSV vaccine, P-KFD1, which protects mice against RSV infection without vaccine-enhanced disease and relies on CD4+ T cell responses mediated by IFN-γ or IL-17A.

This study shows R13, a TrkB agonist, improves mitochondrial function and reduces AD-related pathology in 5xFAD mice by enhancing biogenesis and metabolism.

This study shows maternal obesity differentially programs gene expression in adipose tissues of male and female offspring, contributing to sex-dependent metabolic complications.

The paper identifies two non-canonical GPCRs, D6R and C5aR2, that exclusively couple to β-arrestins and exhibit distinct GRK preferences and downstream signaling.

This study produces SARS-CoV-2 virus-like particles in insect cells for vaccine development and research.

Reduced PAX5 function in mice leads to uncommitted B cell development and B-ALL with secondary mutations in Jak3 and Ptpn11.

Under constant infection by Sclerotinia sclerotiorum, BnaA03.WRKY28 interacts with BnaA09.VQ12 and takes precedence over phosphorylated BnWRKY33 to bind to the BnWRKY33 promoter, thereby weakening resistance but promoting branching.