Y. Kim

The paper shows CDK-2 phosphorylates MSH-5 to promote crossover formation during meiosis by enhancing recruitment of crossover-promoting complexes.

The authors withdrew their manuscript due to inconsistencies in data and questionable experimental results regarding DNA end-resection and chromatin accessibility.

This study evaluates how mutations in SARS-CoV-2 Spike protein affect viral entry and neutralization across animal ACE2 receptors and identifies key mutations that enhance viral entry and reduce antibody neutralization.

The paper identifies PPM-1.D as a phosphatase that antagonizes CHK-2 kinase to regulate meiotic entry through both catalytic and non-catalytic mechanisms.

The paper describes the selection of a SARS-CoV-2 neutralizing antibody from COVID-19 patients using phage display, showing it binds the ACE2-RBD interface and remains effective against emerging RBD mutations.

The paper investigates the impact of the EphA1 P460L mutation on Rho-GTPase signaling in Alzheimer's disease, showing it leads to constitutive receptor activity and dysregulated signaling.

This study shows how mitochondrial-organelle interactions reorganize during skeletal muscle development, shifting from inter-organelle communication to contractile specialization.

This study shows NDR1 is required for drought tolerance and immunity by regulating H+-ATPase activity and stomatal dynamics in Arabidopsis.

This study identifies drug-induced secretome fucosylation as a mechanism of resistance to targeted therapies across multiple cancers.

This paper analyzes proteogenomic data from melanoma patients to show how metastatic melanoma alters metabolism and immune responses to evade immune detection.

This study identifies ERELEE4 as an ORA59-binding cis-element and shows ORA59 regulates JA/ET-responsive genes through direct promoter binding, with differential preference for GCC box and ERELEE4 based on hormone activation.

The paper identifies a Ca2+-activated sphingomyelin scrambling pathway that mediates ESCRT-independent lysosomal repair by converting sphingomyelin into repair intermediates.

This study elucidates the molecular mechanism of substrate recognition by the macrocyclase PsnB in graspetide biosynthesis, revealing key interactions and structural features.

This study identifies systemic tissue and cellular disruption from SARS-CoV-2 infection using autopsy and spatial omics data, showing tissue-specific damage and transcriptional changes.

This study shows that post-infection treatment with a deuterated protease inhibitor improves survival and reduces viral load in mice infected with SARS-CoV-2.

This paper presents a computationally designed dual-ring biobot that demonstrates robust forward motion and rotational steering through differential electrical stimulation.

The paper quantifies cellular density and clustering of immune cells in metastatic ccRCC and finds that CD68+ TAM clustering with tumor cells correlates with worse overall survival.

This study identifies FGFR1's role in SCLC development and growth, showing its dependency on Rbl2 loss and PLCG1 activation.

This study identifies SRSF10 as a host RNA-binding protein that restricts HBV RNA production by interacting with the HBV core protein in the nucleus of infected hepatocytes.

This paper describes engineered prime editors that expand target site range by using PAM-flexible Cas9 variants.

This study identifies and characterizes the pituitary and pineal glands in the Nothobranchius furzeri brain, revealing their anatomical features and cellular composition.

This paper investigates how proton wires in ArcLight-type GEVIs mediate voltage-dependent optical signals through electrostatic interactions and shows that excitation wavelength affects the polarity and kinetics of the response.

This study corrects a disease-causing mutation in a mouse model of tyrosinemia type 1 using ex vivo base and prime editing with chemically derived hepatic progenitors, improving survival rates.

This study evaluates lambda-carrageenan's antiviral effects against influenza and SARS-CoV-2, showing dose-dependent inhibition and protective effects in mice.

This paper develops a mathematical model to study how neutrophil extracellular traps (NETs) influence lung cancer invasion and metastasis, showing that tumor-associated neutrophils enhance invasion via neutrophil elastase secretion and predicting treatment responses.

This study presents the crystal structure of the extracellular region of EsaA, a T7SSb subunit, revealing its role in effector transport across the Gram-positive cell envelope.

This study shows SARS-CoV-2 adapts to Vero E6 cells by losing the furin cleavage motif in spike protein, but retains wildtype sequences, enabling reverse adaptation when passaged on human lung cells.

This paper develops methods to estimate population genetic parameters from serially sampled influenza A/H3N2 sequences, finding high mutation rates and the necessity of recurrent positive selection for HA segment genealogy.

This study identifies and characterizes two prostaglandin-degrading enzymes in Spodoptera exigua, showing their role in regulating immune responses by modulating melanization.

The paper identifies potent SARS-CoV-2 neutralizing antibodies from pre-pandemic human donors that bind the RBD-ACE2 interface, showing high neutralization efficacy in vitro.