Benjamin Steventon

The paper investigates the roles of planar and vertical signals in chick neural development by culturing isolated anterior tissues and shows their necessity for neural specification and anteroposterior patterning.

This study investigates ontogenetic changes in cranial morphology across Galloanserae to understand the developmental basis of cranial disparity between anseriforms and galliforms.

The paper models how progenitor addition and vacuolation interact in zebrafish notochord development, showing a feedback mechanism that maintains tissue proportions during elongation.

The paper shows EMT and BMP signaling interact reciprocally during collective cell invasion, with EMT priming BMP competence and BMP regulating invasion dynamics.

This study identifies fgf8a as a key gene driving brain divergence in Lake Malawi cichlids through species-specific enhancer elements and functional experiments.

This study shows that substrate availability determines the morphogenetic strategy used for body axis elongation in gastruloids, with distinct cytoskeletal dependencies.

The paper introduces a toolkit to analyze cell identity patterning by comparing cells to their neighbors, revealing Notch-dependent heterogeneity in neuromesodermal progenitors.

The paper evaluates the reliability of morphological criteria for staging near-hatching waterfowl embryos and proposes new criteria with higher accuracy.

The paper shows that spinal cord elongation drives proportional regulation of the zebrafish posterior body after neural progenitor reduction.

This study uses live imaging to show mitotic errors and lineage plasticity in human embryos before implantation, revealing implications for aneuploidy mosaicism.

This paper introduces a framework to infer gene regulatory networks (GRNs) during tissue morphogenesis by integrating cell movement and gene expression data.

The paper quantifies cell flows during avian gastrulation using a Dynamic Morphoskeleton model and identifies the mechanistic roles of attractors and repellers in shaping the embryo.

This study shows that mannose is essential for mesoderm specification in gastruloids, while the glycolytic pathway is not required for early T/Bra expression.

The paper identifies a mechanism where Brachyury feedback regulates retinoic acid signaling to drive symmetry-breaking in gastruloids.

The paper shows SARM1 is present in oligodendrocytes but not Schwann cells, and its deletion does not affect myelination in zebrafish or mice.

The paper shows that zebrafish neuromesodermal progenitors undergo a critical state transition in vivo, marked by increased gene expression variability and heterogeneity before differentiation.

The paper shows that variations in Sox2-to-Bra protein ratios in posterior progenitors influence their motility and fate, guiding their contribution to neural or mesodermal tissues.

This study shows that zebrafish presomitic mesoderm elongates through compression and cell density increase, not posterior growth, and tail somites form without PCP signaling.

The paper develops a single-cell morphometrics pipeline to study notochord development in amphioxus, revealing ancestral principles of morphogenesis and growth regulation.

The paper shows that anterior notochord cell expansion and posterior cell addition coordinate to elongate the zebrafish embryo's AP axis through mechanical forces.

The paper shows cell rearrangement during mesoderm elongation generates gene expression patterns through temporal Wnt and FGF exposure.

This paper trains a CNN to stage zebrafish tail buds with small image datasets, achieving high accuracy without large data.

The paper shows that zebrafish embryos can break symmetry autonomously when isolated, indicating that extra-embryonic tissues are not strictly required for early patterning.

The paper identifies a multipotent progenitor population derived from Epiblast Stem Cells that self-renew and express a gene signature similar to embryonic NMPs.

The paper traces neuromesodermal progenitors in zebrafish embryos to show they contribute to spinal cord and mesoderm with distinct growth dynamics across species.

This study compares the ability of mouse ES cell-derived progenitors to generate NMp behavior in vivo, finding that NMp competence is lost in anterior gastruloids.

Mouse embryonic stem cell aggregates (Gastruloids) form anteroposterior, dorsoventral and left-right axes without extraembryonic tissue or localised signals, through Nodal-initiated, Wnt-stabilised T/Brachyury polarisation.