Luke D. Lavis

The paper develops a protein-based ticker tape system to record neural activation histories with high temporal resolution.

The paper develops DELTA, a method to measure brain-wide synaptic protein turnover at single-synapse resolution, revealing localized plasticity in hippocampal CA1 during learning.

The paper studies the kinetic behavior of the GAGA transcription factor in live Drosophila cells, showing it stably binds chromatin for over 2 minutes, independent of chromatin remodelers.

This study uses live-cell imaging in yeast to show how PIC components explore the nucleus and assemble at promoters, revealing spatio-temporal coordination in transcription initiation.

The paper uses single-molecule imaging to study chromatin remodelers in budding yeast, revealing their fast kinetics and ATP-dependent dissociation from chromatin.

The paper describes engineering eFRET voltage indicators with positive-going fluorescence responses by modifying microbial rhodopsins.

The paper uses live-cell single particle imaging to show that RNA polymerase II and Kin28/Cdk7 kinase are required for H2A.Z eviction in yeast, linking it to transcription processes.

This study uses super-resolution imaging to reveal the 3D structure and organizing mechanism of accessible chromatin domains.

The paper introduces a new platform for chemigenetic fluorescent indicators with bright, far-red emission and tunable properties for detecting single action potentials in neurons.

The paper introduces a new genetically encoded voltage indicator, Voltron, which improves brightness and photostability for extended in vivo voltage imaging in mice, zebrafish, and fruit flies.

This study shows that VTA glutamate neurons express nicotinic acetylcholine receptors and are modulated by cholinergic input, affecting excitatory transmission.

This paper develops a method to create photoactivatable nicotine for optopharmacology studies of nicotinic acetylcholine receptors.