Kei Ito

Breaking Symmetry in Walking: Drosophila Recruits Task- and Leg-Specific Motor Modules for Curve Walking

This study identifies task- and leg-specific motor modules in Drosophila that enable curve walking by reconfiguring leg kinematics for arcs and turns.

Pathway-Centric Integration of CRISPR Fitness with Molecular Features Draws Cancer State Maps

StateMap integrates CRISPR fitness and gene expression data to map cancer pathway states, identifying therapeutic vulnerabilities in the Hippo pathway.

A dedicated brain circuit controls forward walking in Drosophila

This study identifies a dedicated brain circuit in Drosophila that controls forward walking by initiating movement and modulating speed, independent of turning behaviors.

A split-GAL4 driver line resource for Drosophila neuron types

The paper describes a collection of split-GAL4 driver lines for targeting specific neuron types in Drosophila, enabling functional and molecular studies.

Single-cell type analysis of wing premotor circuits in the ventral nerve cord of Drosophila melanogaster

The paper identifies 196 cell types in the Drosophila ventral nerve cord using split-GAL4 and links them to a connectomic dataset for circuit analysis.

BigNeuron: A resource to benchmark and predict best-performing algorithms for automated reconstruction of neuronal morphology

BigNeuron benchmarks automatic neuron reconstruction algorithms using gold standard annotations and image quality metrics, showing that consensus methods outperform individual algorithms.

An unbiased template of the Drosophila brain and ventral nerve cord

This paper creates high-resolution brain and ventral nerve cord templates for Drosophila using advanced imaging and registration techniques, showing improved accuracy and efficiency compared to existing templates.

Input connectivity reveals additional heterogeneity of dopaminergic reinforcement in Drosophila

The paper identifies anatomical subtypes of dopaminergic neurons in Drosophila and their specific input connectivity, revealing functional roles in reinforcement and memory.

Conservation and Divergence of Related Neuronal Lineages in the Drosophila Central Brain

The paper maps Drosophila central brain lineages to show how lineage identity and temporal patterning drive neuronal diversity and complexity.

A Connectome of the Adult Drosophila Central Brain

A dense electron-microscopy reconstruction of half the fly central brain, with nearly every cell typed and queryable online, turns months of tracing partners into a database lookup.

A lineage-related reciprocal inhibition circuitry for sensory-motor action selection

The paper identifies a lineage-related reciprocal inhibition circuit in Drosophila that mediates sensory-motor action selection through competitive inhibition.