Xenopus

The paper studies how cytoplasmic organization affects protein diffusion using Xenopus laevis egg extracts, finding that organization increases diffusion speed for protein-sized molecules.

This study identifies microRNAs in Xenopus laevis that regulate antiviral immunity and immunoevasion by ranavirus.

This study investigates how RNA-protein interactions drive the recruitment and dynamics of RNA-binding proteins in Xenopus oocyte biomolecular condensates.

The paper investigates antiviral responses in Xenopus laevis skin epithelial cells to Frog Virus 3 (FV3) and finds that poly(I:C) pretreatment limits FV3 replication.

The paper shows that mechanosensitive calcium flashes trigger RhoA activation, leading to tight junction remodeling in response to mechanical stress in Xenopus laevis epithelial cells.

The paper identifies SSX2IP as a Wtip-binding partner using targeted proximity biotinylation and shows their interaction forms phase-separated aggregates.

This study identifies Lmo7 as a scaffold that recruits myosin II to apical junctions, promoting apical constriction in Xenopus ectoderm.

This study shows that tubulin acetylation enhances the penetrative capacity of cells during radial intercalation in Xenopus embryos by influencing their ability to insert into epithelial barriers.

This study uses RNA-Seq to analyze FV3-infected Xenopus tissues, identifying viral gene expression patterns and molecular mimics of host IFN signaling components.

The paper measures microtubule depolymerization rates in Xenopus egg extract asters and finds higher rates in the interior compared to the periphery, suggesting regulation by MAP depletion.

The paper investigates how increased crowding affects cytoplasm demixing in Xenopus egg extracts, showing glycogen-rich phases form and are influenced by glycogen hydrolysis.

This study creates an artificial cell cortex using Xenopus egg extract and lipid bilayers to observe self-organizing Rho and F-actin dynamics similar to those in vivo.

The paper studies fluid transport in mosaic ciliated tissues, finding that hydrodynamic interactions limit work efficiency and optimal shearing occurs at low area coverage.

This study identifies Nup50's role in mitotic NPC assembly through its interaction with RCC1, independent of its nuclear transport function.

This paper introduces two new photoswitchable reagents for in vivo control of microtubule dynamics and related processes, showing their effectiveness in 3D systems and model organisms.

This study investigates the role of DDK and Treslin-MTBP in coordinating replication licensing and pre-Initiation Complex formation in Xenopus egg extract.

This study shows that Yersinia pestis uses Ara4N modification of LPS to resist cheopin, an antimicrobial peptide from fleas.

The paper investigates the presence of the Balbiani body in mouse primordial oocytes and finds it absent, instead identifying a ring-shaped Golgi apparatus as a previously misinterpreted marker.

The paper shows PP2A-B55 acts as a bistable switch and is regulated biphasically by Cdk1, influencing mitotic substrate phosphorylation dynamics.

This study shows that frog nest foams have stable, biocompatible properties and can encapsulate compounds like antibiotics, suggesting potential for pharmaceutical applications.

This study shows H1.8 inhibits condensins and topo II to regulate chromosome length and individualization during mitosis.

This study identifies the chemical structure of aryl polyene lipids (APELs) from Xenorhabdus doucetiae using chromatographic purification and structural analysis techniques.

This paper uses single-pair FRET to show that the linker histone H1.0b binds on-dyad to A-tract DNA via minor groove recognition, revealing a new mechanism for AT-rich DNA binding.

The paper shows that microtubule nucleation, not polymerization, governs spindle scaling across all cell sizes by regulating nucleation inhibitor partitioning to the cell membrane.

This study reconstitutes the β-adrenergic regulation of CaV1.2 channels in a heterologous system, identifying Rad-dependent and Rad-independent PKA mechanisms.

The paper quantifies how specific histone H4 acetylation sites affect chromatin transcription rates using a reconstituted system and kinetic modeling.

This study investigates how temozolomide induces DNA double-strand breaks through crosstalk between repair pathways in Xenopus egg extracts.

The paper identifies a three-step mechanism for resolving G-quadruplex structures during DNA replication using Xenopus egg extracts.

The paper clones and characterizes a non-olfactory shark adenosine receptor (A0) that activates CFTR with unique pharmacology and structural features, suggesting evolutionary links to mammalian ADORs.