zebrafish

The paper introduces a zebrafish model and computational framework to systematically analyze cancer metastasis patterns across organs, revealing heterogeneity and spatial preferences in dissemination.

This study examines haploid-induced tissue defects in zebrafish larval eyes, revealing disorganized cellular structures and impaired photoreceptor and ganglion cell organization.

This study shows that chronic FMNL2 overexpression in zebrafish causes brain histological changes and altered exploratory behavior similar to those seen after acute Aβ42 exposure.

This study uses live imaging in zebrafish to show that hindbrain medulloblastoma cells spread more frequently than forebrain or midbrain tumors and that dasatinib reduces dissemination.

This paper introduces a new two-photon fluorescence lifetime imaging technique for rapid volumetric imaging of biological samples with high resolution and low phototoxicity.

This study compares oogenesis in annual and non-annual killifishes, finding conserved developmental stages but divergent zona pellucida features in the annual species.

This study develops an assay in larval zebrafish to investigate visual desensitization and its role in synaptic plasticity by measuring escape responses to varying visual stimuli.

This study identifies clathrin-coated endocytic tubules in lysosome-rich enterocytes that enable rapid and selective protein uptake in zebrafish and mice.

The paper uses live-cell imaging to study neural network development in zebrafish, revealing conserved structural dynamics and optimization strategies.

This study shows that sharks and rays have cartilage canals in their adult skeletons, which are vascular but do not trigger endochondral bone formation, suggesting an ancient role in nutrient transport.

NeuroPack compresses 3D neuroimaging data with high fidelity and ultra-high compression ratios using a hyperprior-driven deep learning toolkit.

This study shows that early paroxetine exposure in zebrafish embryos causes transient apoptosis, delayed neurogenesis, and brain remodeling linked to ASD-like social behavior impairments.

Zebrafish larva infection experiments plus pharmacokinetic-pharmacodynamic (PKPD) modelling gave bedaquiline's in vivo Emax and EC50 against M. marinum in about 2 months; waterborne clarithromycin barely entered larvae.

Region-stratified scRNA-seq of 607,370 cells plus 500-gene MERFISH maps adult Danionella cerebrum cell types body-wide, revealing fibroblast Hox and limb-identity programs and telencephalon regeneration dynamics.

This study uses a zebrafish model of Marfan syndrome to identify potential therapies through a high-throughput drug screen and luminescence-based phenotyping.

This paper introduces MINI2P-II, a lightweight 2P miniscope enabling multi-region calcium imaging in freely moving animals with high resolution and dual-color capability.

The paper compares saccadic suppression strength between macaques and zebrafish, showing it reflects differences in sensory and motor noise levels and computational resource allocation.

This study quantifies spatial asymmetry in zebrafish pectoral fin regeneration, revealing differential gene expression and signaling dynamics between anterior and posterior regions.

This study shows that grooming movements in rhesus macaques are adapted from feeding movements, with similar hand motions used for both tasks.

Blender tissue cartography provides an intuitive tool for analyzing dynamic 3D microscopy data by converting complex 3D tissues into 2D projections for easier visualization and analysis.

This paper introduces a framework using Hidden Markov Models with Step Selection Functions to infer behavioural states from movement and environmental data, showing improved accuracy in identifying ecologically meaningful states.

This study uses live imaging in zebrafish to show that cone outer segments are removed in small, successive particles at the cone-RPE interface without extracellular accumulation.

The paper introduces an open-source VR platform for head-fixed adult zebrafish to study behavior and neuronal activity in controlled virtual environments.

BeatRatePy quantifies beat rate, contraction, and speed from label-free cardiac imaging data, showing consistent performance across different systems and datasets.

This study shows how measurement practices affect repeatability estimates of individuality in clonal fish, highlighting methodological influences over biological variation.

gene2fish arranges 53,595 Thisse in situ hybridization images of 8,263 zebrafish genes into a gene-by-stage grid, with anatomy-term search for validating scRNA-seq markers.

The paper introduces FORCENET, an implantable sensor network that maps intercellular forces in living embryos, revealing coordinated mechanical patterns regulated by developmental signaling.

The paper introduces β-Stability, a graph-based framework for semi-automated curation of animal identities from images, achieving high accuracy with limited expert review.

The paper develops a new whole slide image analysis method to detect and quantify hepatocellular vacuolization in European flounder exposed to multiple pollutants, showing significant differences between polluted and control sites.

This study characterizes brain maturation in larval zebrafish using brain-wide imaging, revealing changes in functional connectivity, network organization, and cellular activity patterns.