Topic · Endocrinology, Diabetes and Metabolism · Medicine
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
13 papers
Xufu Liu, Liying Luo, Laura Pritschet, Yutong Mao, Feng Han, David N. Proctor, Xiao Liu
This study finds that early menopause is associated with reduced global brain activity and weaker coupling to CSF flow, linked to memory decline and increased dementia risk.
npj Aging · Jul 31, 2026Peer-reviewedNeuroscience
Nadja Knox, Ali Yasrebi, Daniel Caramico, Katherine A. Denney, Kimberly Wiersielis, Benjamin Adam Samuels, Troy Adam Roepke
This study examines how diet-induced obesity and chronic stress interact in a mouse model of menopause, showing increased cognitive impairments and metabolic changes in VCD-treated HFD-fed mice.
Hormones and Behavior · May 14, 2026Peer-reviewedNeuroscience
Sebastian F. Salathe, Edziu Franczak, Zane Busick, Frederick B. Boakye, Julie Allen, Andrew J. Lutkewitte, Heather Wilkins, John P. Thyfault, Benjamin A. Kugler
This study shows that estrogen therapy restores synaptic and metabolic proteins in the brain of aged mice after ovariectomy, improving mitochondrial function and synaptic integrity.
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · Apr 2, 2026Peer-reviewedNeuroscience
Kathryn E. Werwath, Rebecca B. Lawn, Madeleine Salem, Tayden Li, Brittany L. Mitchell, Hanyang Shen, Scott D. Gordon, Benson Kung, Ciera Stafford, Mytilee Vemuri, Andrew D. Ratanatharathorn, Joeri J. Meijsen, Aladdin H. Shadyab, Charles L Kooperberg, Karestan Chase Koenen, , Laramie E. Duncan
This paper conducts a trans-ancestry GWAS of hot flashes, identifies TACR3 as a key genetic target, and finds genetic overlaps with psychiatric disorders.
Communications Medicine · Jan 6, 2026Peer-reviewedGenetic & Genomic Medicine
Maria C. Tickerhoof, Heining Cham, Laila Ouldibbat, Anaya Ger, Sonola Burrja, Pavan Kumar Auluck, Peter J. Schmidt, Stefano Marenco, Marija Kundaković
This study identifies biomarkers in postmortem tissues to determine menopausal status, enabling research into MT-related brain disease risks.
Molecular Psychiatry · Aug 27, 2025Peer-reviewedNeuroscience
Christian Montanari, Emma L Dong, Shruti Srinivasan, Ana Paula de Oliveira Leite, Alyssa F. DeLarge, Matthieu J. Maroteaux, Lucie Delphine Desmoulins, Riva Menon, Alice B Walker, Sarah Hoffmann Lindsey, Andrea Zsombok, Jill M. Daniel
This study shows that estradiol improves cognitive aging in rats independently of its effects on cardiometabolic health.
Endocrinology · May 19, 2025Peer-reviewedAnimal Behavior & Cognition
Abigail E. Salinero, Harini Venkataganesh, Charly Abi‐Ghanem, David A. Riccio, Richard D. Kelly, Olivia J. Gannon, Avi Sura, Heddwen L. Brooks, Damian G. Zuloaga, Kristen L. Zuloaga
This study shows that menopause worsens metabolic issues in mice on a high-fat diet, with greater effects in middle-aged mice.
International Journal of Obesity · Aug 16, 2024Peer-reviewedNeuroscience
Rikki Lissaman, Sricharana Rajagopal, Julia Kearley, Stamatoula Pasvanis, Maria Natasha Rajah
The paper examines how menopause status and sex influence age-related changes in spatial memory and white matter microstructure in midlife adults.
Neurobiology of Aging · Jun 8, 2024Peer-reviewedNeuroscience
Hanna‐Kaarina Juppi, Tia-Marje K. Korhonen, Tero Sievänen, Vuokko Kovanen, Urho M. Kujala, Pauliina Aukee, Neil J. Cronin, Sarianna Sipilä, Sira M. Karvinen, Eija K. Laakkonen
The paper examines how the menopausal transition affects the skeletal muscle transcriptome in women, identifying differentially expressed genes and regulatory networks linked to body composition changes.
Translational Exercise Biomedicine · Mar 12, 2024Peer-reviewedMolecular Biology
Ann‐Marie G. de Lange, Cláudia Barth, Tobias Kaufmann, Ivan I. Maximov, Dennis van der Meer, Ingrid Agartz, Lars Tjelta Westlye
This study examines how sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease influence brain aging in women using UK Biobank data.
Human Brain Mapping · Aug 28, 2020Peer-reviewedNeuroscience
Liisa A.M. Galea, Meighen Roes, Christina J. Dimech, Carmen Chow, Rand Mahmoud, Stephanie E. Lieblich, Paula Duarte‐Guterman
This study shows that Premarin affects spatial learning, neuronal activation, and cytokine levels differently in middle-aged rats based on their reproductive history.
Neurobiology of Aging · Jun 30, 2018Peer-reviewedNeuroscience
Mark G. Baxter, Anthony C. Santistevan, Eliza Bliss‐Moreau, John H. Morrison
This study shows that starting estradiol treatment more than 2 years after menopause in aged rhesus monkeys improves cognitive function, while stopping treatment later does not reduce cognitive benefits.
Behavioral Neuroscience · Jun 28, 2018Peer-reviewedNeuroscience
The paper explores using commercial activity tracking watches to continuously monitor electrodermal activity for individuals experiencing vasomotor symptoms, aiming to improve upon diary-based tracking methods.
F1000Research · Dec 20, 2017Peer-reviewedBioinformatics