H. Liu

This study investigates how heterologous synapsis in C. elegans is regulated by meiotic double-strand breaks and crossovers, showing that reduced breaks or crossovers increase synapsis promiscuity.

This study tests air nanobubbles' effectiveness in reducing pathogenic bacteria in water but finds no significant bacterial reduction.

The paper compares vaccine efficacy against Delta and Lambda SARS-CoV-2 variants, finding Lambda has greater escape potential, with reduced antibody reactivity and therapeutic antibody binding.

This study develops genome-wide lncRNA-derived SSR markers for Dongxiang wild rice and validates their polymorphism and utility in genetic diversity analysis and breeding.

This study examines how dietary fiber affects gut microbiome dynamics and SCFAs in mice, showing baseline-dependent responses and the importance of ecological modeling.

The paper screens cell-virus and cell-cell interactions across multiple species to identify potential hosts and co-evolution patterns of viruses including SARS-CoV-2.

N-dihydrogalactochitosan reduces mortality and morbidity in a lethal SARS-CoV-2 mouse model by lowering viral load and improving survival.

This study identifies how the parasite Toxoplasma gondii uses the disordered protein TgIST to block STAT1-mediated gene expression by altering STAT1 dimer conformation and preventing activator recruitment.

This paper develops a novel PROTAC, ZL216, using an aptamer as a targeting ligand to selectively degrade nucleolin in breast cancer cells, inhibiting their proliferation and migration.

This study develops a gadolinium-free MRI contrast agent targeting Oatp1 channels for liver imaging, showing improved relaxivity and specific signal changes in mice.

The paper uses single-cell transcriptomics to profile viral receptor expression in masked palm civets, identifying potential tissue tropisms for 132 viruses.

The paper identifies Rhodanese 2 (Rdl2) as critical for protecting mitochondria from hydroxyl radical damage in yeast by converting sulfur species into reactive sulfane sulfur.

This study analyzes the gut microbiomes of two stingless bee species, finding that bacterial richness in T. carbonaria correlates with host wing size and geography.

This study quantifies how Vibrio cholerae lands on surfaces in viscoelastic environments using MSHA pili and flagellum, showing pili act as brakes and anchors during landing.

ASER compiles sex reversal data from 18 species, including genes, regulatory networks, RNA-seq, and ISH images, to support research on animal breeding and human health.

This study shows ARID1A loss activates HERVH, which promotes tumor growth by modulating BRD4-dependent transcription in colorectal cancer.

This paper identifies a novel flight style in miniature featherwing beetles that enables high-speed flight despite their small size, offering insights for micro aerial vehicle design.

This study uses single particle mass analyses to examine antibody binding to the SARS-CoV-2 spike protein, revealing sub-stoichiometric binding and its effectiveness in blocking ACE2.

This study shows TRAF2 regulates mitophagy and inflammation in cardiac myocytes to prevent cell death and maintain homeostasis.

This study develops a molecular dynamic fingerprint (MDFP) and combines it with traditional fingerprints to predict hERG cardiotoxicity, achieving higher accuracy than single-fingerprint models.

This paper develops a machine learning model using Raman spectroscopy to accurately identify viruses, achieving high accuracy in classifying virus types and subtypes.

This paper introduces a new HMM algorithm that improves accuracy and objectivity in analyzing biophysical data with many states, achieving faster performance and better handling of complex datasets.

This study examines co-infection with Heligmosomoides bakeri and Toxoplasma gondii, finding increased mortality and intestinal pathology in co-infected mice.

This study shows that SARS-CoV-2 Nsp14 activates NF-κB signaling and increases IL-8 expression, which is confirmed in infected cells and lung tissue from COVID-19 patients.

This paper introduces MLC-Seq, a method to sequence full-length tRNA isoforms and quantify RNA modifications, demonstrating its application on yeast and mouse tRNAs.

This study investigates how high temperatures affect meiosis in autotetraploid Arabidopsis thaliana, revealing that heat stress disrupts chromosome axis stability and meiotic recombination.

This paper identifies PRC2-mediated epigenetic repression as critical for regulating gene expression during biotrophic growth in M. oryzae, with Pmk1 coordinating this process by modulating Suz12.

This study shows that the B.1.1.7 SARS-CoV-2 variant replicates and sheds more efficiently in hamsters' nasal cavities than earlier D614G variants with lower doses and shorter exposure.

This study identifies MARCH1 and MARCH8 as specialized regulators of CD4+ T cell immunity in distinct cellular compartments by analyzing their substrates and expression in mice.

This study identifies procyanidin C1 as a natural senolytic agent that selectively kills senescent cells and improves healthspan in aged animals.