J. Liu

The paper studies how molecular interactions in the actomyosin cortex of sea star oocytes control cell shape changes through active mechanics and viscosity.

This study investigates the structural and biochemical features of Omicron BA.1 and BA.2 variants, showing increased infectivity and mouse ACE2 binding compared to wildtype, suggesting a potential human-cat-mouse-human transmission cycle.

This study identifies climate-associated genetic variants in Populus koreana and predicts its future climate change vulnerability using genomic and environmental data.

This study shows that collagen remodeling via MMP cleavage affects pancreatic cancer bioenergetics and outcome through DDR1 activation or degradation, with distinct impacts on tumor growth and survival.

This study shows that nuclear import of Gdown1 modulates global transcription and enhances cellular stress tolerance.

The paper withdraws due to the need for further experiments to validate conclusions about Bfl-1 and HDAC inhibition in diffuse large B cell lymphoma.

This study examines gene expression changes in Saccharibacteria TM7x and its host during symbiosis establishment, revealing dynamic interactions and functional roles in maintaining the relationship.

This paper scales PhIP-Seq for autoantibody discovery across multiple autoimmune diseases and COVID19, enabling machine learning predictions and identification of disease-specific autoantigens.

The paper evaluates the global impact of mining construction minerals on biodiversity, identifying 1,047 threatened species and 234 new species descriptions affected by mining.

This study analyzes gene mutations in CHIKV E1 and E2 proteins from 2014 to 2019, identifying common mutation sites and their potential impact on immune escape and serological detection.

This study shows that M2 macrophage-derived extracellular vesicles reduce cytokine storm by targeting multiple pathways and can act as nanodecoys against SARS-CoV-2.

This study shows that asymmetric ABA response in tomato root tips mediates proton efflux and cell elongation, driving hydrotropic bending toward water.

This study shows that alveolar regeneration after viral infection occurs independently of tuft cells, with ectopic basal progenitor cells generating alveolar epithelial cells through distinct differentiation paths.

This study quantifies the tension-dependent lifetime of tension gauge tethers to better understand their mechanical stability under physiological stretching conditions and reinterprets previous experimental observations.

The paper presents the first in situ evidence for a bridge-like structure of VPS13C at ER-lysosome contacts, supporting its role in lipid transport.

This paper introduces RLN, a deep learning method for 3D fluorescence microscopy deconvolution that improves speed, performance, and generalizability compared to existing methods.

This paper introduces a method to control CRISPR-Cas gene editing using light-activated circular guide RNAs, enabling precise spatial and temporal gene editing in cells and embryos.

This study edits the MeSWEET10a promoter in cassava to confer resistance to bacterial blight without affecting yield traits.

This study evaluates the neutralization efficacy of antibodies against SARS-CoV-2 Omicron and other variants, finding that antibody 8G3 maintains broad neutralizing activity while EUA antibodies lose effectiveness.

The paper demonstrates how structural hierarchy and protein hydration in the cornea of horseshoe crabs enable efficient light collection through graded index optics and total internal reflection.

This paper describes a live-attenuated SARS-CoV-2 vaccine candidate with deleted ORFs that shows reduced replication and attenuation in animal models, and reports its protective efficacy against wild-type virus challenge.

This study identifies ORANGE family proteins as regulators of chlorophyll and carotenoid biosynthesis in plants, showing their role in coordinating these pathways for photosynthesis and thermotolerance.

This study identifies OXI1 and AGC2-2 as kinases that phosphorylate PDR6, enhancing camalexin efflux and disease resistance in plants.

This study evaluates vaccine efficacy against SARS-CoV-2 Omicron in macaques, finding that both humoral and cellular immune responses are necessary for virologic control.

This study uses single-cell RNA sequencing to identify five MSC subpopulations, revealing distinct developmental trajectories and functional roles in self-renewal and immunoregulation.

This study shows that aucubin promotes functional recovery after spinal cord injury by reducing inflammation and neuronal apoptosis through the TLR4/NF-κB pathway and mitochondrial protection.

This study demonstrates that selective PIN1 inhibition in CAFs and engagement of T lymphocytes using a bispecific system effectively eradicates pancreatic tumors in mice.

This study sequenced the genome of Monascus purpureus to identify secondary metabolite gene clusters and chitin synthesis pathways, and confirmed plasma-induced gene expression.

This study shows that a poxvirus lacking the host range determinant M062 activates cGAS-dependent type 1 interferon responses and induces unique transcriptomic changes in human macrophages.