S. Yang

This study shows that fascin promotes lung cancer growth and metastasis by enhancing glycolysis through YAP1-PFKFB3 activation.

This study shows MyD88 is essential for M cell differentiation in colitis and RANKL-induced conditions in mice.

This paper develops a cellulose-based method using nanobodies to capture and neutralize SARS-CoV-2 pseudoviruses, showing effectiveness against wildtype and D614G variants.

The paper screens cell-virus and cell-cell interactions across multiple species to identify potential hosts and co-evolution patterns of viruses including SARS-CoV-2.

The paper investigates how overlapping genes in HIV-1 balance selective forces, finding functional segregation where each protein spaces its residues to accommodate the other's functional sites.

The paper identifies lncEry, a long non-coding RNA that regulates mouse erythroid differentiation and maturation by interacting with WDR82 to control Klf1 and globin gene transcription.

This paper introduces a CRISPR-nCas3 system for efficient genome editing in bacteria, enabling high-efficiency deletion of large genomic regions.

This paper demonstrates the ability to forecast decadal-scale shifts in marine fish habitats using climate predictions, showing skill that outperforms persistence and climatological baselines.

This paper demonstrates that intranasal and injectable CMV-based gene therapy can extend lifespan and improve health in mice by overexpressing TERT and FST.

This study uses single-cell transcriptomics to identify novel cell populations and functional differences in human nucleus pulposus during degeneration, revealing potential regenerative and immunosuppressive roles.

This study constructs high-resolution spatial transcriptomes of primary liver cancers to analyze spatial architecture and identify tumor microenvironment features.

Overexpression of VDAL in Arabidopsis enhances resistance to Verticillium dahliae by preventing degradation of the transcription factor MYB6 through interaction with PUB25/26 E3 ligases.

This study identifies a malaria parasite phospholipid flippase, ATP7, as essential for ookinete survival in mosquito midgut epithelium, revealing its role in membrane asymmetry maintenance and transmission.

ZF2001, a tandem-repeat dimeric RBD protein vaccine, induces strong immune responses and protects mice and non-human primates from SARS-CoV-2 infection.

This paper combines adaptive optics with single-molecule localization microscopy to achieve sub-100 nm resolution imaging of phosvitin in turbid food emulsions.

This study evaluates the impact of different sterilization methods on the properties of a conjugated polymer-based bioelectronic patch, finding that ethylene oxide and low-dose gamma irradiation best preserve its performance and minimize immune response.

This study shows pepper activates two different immune systems against Ralstonia solanacearum under high temperature and humidity, regulated by CaWRKY40 and cytokinins.

This study examines how positive and negative emotions affect false memory using EEG, finding higher false memory rates and distinct brain activation patterns in the positive emotion group.

This study identifies a brain-muscle signaling axis activated by infections and chronic diseases that reduces muscle performance through cytokine-dependent mechanisms.

Single-cell multi-omic profiling identifies immune dysregulation in severe COVID-19, including neutrophil hyperactivation and anti-inflammatory monocytes.

This study identifies abundant and diverse circRNAs from SARS-CoV-2, SARS-CoV, and MERS-CoV, revealing a novel type of circRNA distinct from DNA-encoded circRNAs.

The paper shows that epithelial cell reintegration uses a mechanism similar to axon pathfinding, involving IgCAMs and mechanical coupling to the membrane skeleton.

The paper expands the human gut microbiome reference database by incorporating newly assembled genomes from under-represented Asian populations, improving taxonomic and functional classification and revealing associations with autoimmunity.

This study shows SATB2 drives melanoma invasion and drug resistance by inducing a neural crest mesenchyme-like transcriptional program in zebrafish and human models.

This paper introduces spatially expandable fiber-based probes for deep brain interface, enabling three-dimensional recording and stimulation of neural activity with high resolution and minimal tissue damage.

This study analyzes fungal communities in Chinese Marselan wine fermentation across regions, finding that environmental factors significantly influence fungal composition and fermentation performance.

This study identifies marrow adipogenic lineage precursors (MALPs) as critical regulators of osteoclastogenesis through RANKL expression, showing their role in both normal bone remodeling and pathologic bone loss.

This study identifies an IL1β/NFκB/ESE3 signaling axis in pancreatic stellate cells that drives fibrosis, chemoresistance, and poor prognosis in pancreatic cancer.

The paper shows HOXB13 expression is reduced or lost in neuroendocrine prostate cancer (NEPCa) and that NEPCa tumors lose prostate-specific HOX codes without gaining a clear new tissue identity.