T. Li

This study uses 5' capture scRNAseq to detect and quantify DENV RNA in infected cells, revealing viral sequence variability and identifying infected cell types.

This study identifies mosquito and mouse saliva as inhibitors of TRPV1 and TRPA1 channels, with sialorphin as a candidate antinociceptive peptide, and confirms antinociceptive effects in vivo.

This study shows that Asgard archaea possess ESCRT complexes with eukaryotic-like structural and functional features, suggesting they are evolutionary precursors to eukaryotic ESCRTs.

This study examines how Fugacium kawagutii responds to nitrogen deficiency and different nitrogen forms, finding ammonium is preferentially used and identifying stable reference genes for future studies.

This paper demonstrates that enzyme nanoclusters can depolymerize polyesters via chain-end mediated processive degradation, enabling scalable bioactive plastics for efficient sorting.

This study shows that filamentous viral particles have a functional advantage over spherical ones in resisting neutralizing antibodies and fusion inhibitors.

This study shows that antibodies from SARS-CoV survivors and immunized animals neutralize SARS-CoV-2, suggesting potential for broad-spectrum vaccines against emerging coronaviruses.

The paper withdraws its manuscript due to the need for further experiments to validate conclusions.

This paper develops freeze-dried PCR mixes for SARS-CoV-2 detection that can be stored at room temperature, maintaining sensitivity and specificity for up to 28 days.

The paper presents a spiking neural network model showing how time-integrated spatial views in the dorsal visual pathway enable panoramic representations for memory-based spatial reorientation and visual search.

This study shows that VDR and STAT3 cooperate with TET2 to induce DNA demethylation and tolerogenesis in dendritic cells through vitamin D signaling.

The paper uses single-cell RNA sequencing to analyze stomatal lineage cell development in Arabidopsis, identifying new marker genes and transcriptional networks.

This study develops a recombinant ACE2-Ig fusion protein that neutralizes both SARS-CoV and 2019-nCoV in vitro, showing cross-reactivity and potential for diagnostic, prophylactic, and therapeutic applications.

This study compares spindle dynamics in mitosis and meiosis I using fission yeast, showing Klp2 maintains meiotic spindle stability with Ase1, but not mitotic spindles.

This paper introduces Random Illumination Microscopy (RIM), a super-resolution technique that achieves high-resolution, low-toxicity, and fast imaging for live-cell studies.

The paper develops a high-affinity sPD-1 decoy molecule that neutralizes both PD-L1 and PD-L2, showing superior antitumor activity in ovarian cancer models compared to PD-1/PD-L1 antibodies.

This study shows Aurora B and condensin are not required for telomere and chromosome arm separation during meiosis II in fission yeast.

This paper identifies and characterizes 359 RXLR effectors in nine Pythium species, revealing evolutionary patterns and functional roles in host interactions.

This study applies r- and K-selection to HeLa cells to show how life history strategies influence tumor functional diversity through gene expression and ecological competition.

The paper develops a domain-specific CRISPR-Cas9 system with live-imaging screening in Arabidopsis to study PIN1 function in tissue morphogenesis and mechanical stress response at single-cell resolution.

This study identifies aberrant DNA methylation in mesenchymal stromal cells from myeloma patients and shows that targeting DNMTs and G9a with CM-272 reverses bone loss and reduces tumor burden.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

This study shows cediranib inhibits Mycobacterium tuberculosis ClpP1P2 by targeting its equatorial handle domain, revealing conformational changes critical for its function and suggesting a strategy for species-specific inhibitors.

This study shows that TIGIT-Ig treatment delays lupus onset, reduces autoantibodies, and improves survival in mice, suggesting potential for human autoimmune disease therapy.

The paper identifies co-occurring RAS-MAPK pathway alterations in MET exon 14 skipping mutation positive lung cancers that limit response to MET inhibitors and suggests combining MET and MEK inhibitors to overcome resistance.

This study shows that climate change has caused a northward shift in the range of wheat pests, leading to increased crop damage despite pesticide use.

The paper develops improved CRISPR/Cas9 methods for genome editing in Culex quinquefasciatus, achieving higher embryo survival and germline mutagenesis rates.

This study presents a neural network model of the hippocampal-entorhinal loop to investigate how visual and self-motion cues influence spatial representation in multi-compartment environments.

The paper uses shotgun metagenomics to analyze the gut microbiome in AS patients, finding enriched bacterial epitopes linked to HLA-B27 and effects of TNFi therapy and host genotype on microbiome composition.