X. He

This study identifies gene expression changes and pathways involved in passion fruit ripening and senescence using RNA sequencing and validates findings with RT-qPCR.

This study analyzes S:A ratios across species to understand dosage compensation mechanisms in sex chromosomes, finding clade-specific patterns and supporting the sex chromosome insensitivity hypothesis.

This study captures novel genomes from Saccharibacteria groups in humans and mammals, revealing convergent evolution and independent adaptation to human hosts.

The paper links species traits to extinction risk across diverse taxa, identifying key traits that predict vulnerability to extinction globally.

This study shows that exogenous melatonin administration restores diurnal rhythms in gut microbiota and host metabolism in high fat diet-fed mice.

This paper develops a computer-aided method to assess growth ring boundaries in softwood using image processing, achieving 98% accuracy by analyzing 100 micro-images.

The paper compares tumor and normal single-cell mRNA data to show neuroblastoma cells resemble fetal sympathoblasts across diverse samples.

This paper develops a laser-activated drug implant for controlled release in the posterior eye, showing in vitro and in vivo drug release kinetics and safety.

This study shows that loss of Aldob activates Akt, promoting hepatocellular carcinoma by destabilizing the Aldob/Akt/PP2A complex, and identifies SMAP as a potential therapeutic agent.

The paper investigates SARS-CoV-2 infection in cats by detecting serum antibodies, finding 14.7% of post-outbreak samples positive for RBD and 11 with neutralizing antibodies.

This study identifies expanded microbial and autoantigen antibody repertoires in TIF1γ-positive dermatomyositis, revealing viral enrichment and epitope homology with TRIM proteins.

This study analyzes mRNA signals in 1,300 kidney tumors to determine their differentiation state and origin, finding that childhood tumors show fetal signals while most adult tumors do not, with exceptions in certain cancer types.

The paper constructs an adult human cell atlas from 84,363 cells across 15 organs, identifying 252 cell subtypes and revealing inter- and intra-organ heterogeneity.

This study shows that deleting or inhibiting OCA-B in T cells protects mice from type-1 diabetes by reducing autoreactive CD8+ T cells and inducing anergy in CD4+ T cells.

This study shows that mechanical alignment of actin filaments precedes chemical changes during bundle formation in response to tensile force.

This study identifies adaptive divergence followed by population admixture as a source of additive genetic variance in evolutionarily important traits, showing a strong positive correlation between heritability and evolutionary importance.

This study shows that ANXA2 depletion increases CMHs in rickettsia and Ebola virus infections by disrupting BBB tight junctions.

This paper proposes an electrostatic-interaction-based mechanism for prion protein refolding from PrPC to PrPSc, identifying key steps involving hydrophobic interactions and pH changes.

This study compares the hypocholesterolemia effects of four probiotic strains with atorvastatin in a high-fat diet model, showing probiotics are less effective but alter gut microbiota differently.

This study identifies a comprehensive atlas of B-lymphocytes in triple-negative breast cancer using single-cell RNA-sequencing and antigen receptor profiling, revealing their mature characteristics and prognostic significance.

This study shows ionomycin treatment rescues osteoporosis in HPP by restoring Ca2+ influx via ALPL-mediated L-type Ca2+ channel trafficking in BMSCs.

The paper describes modifications to the Illumina HiSeq 2500 platform for higher throughput amplicon sequencing with improved quality and multiplexing capabilities.

The paper shows that fission yeast can accumulate biomass without expanding in volume, leading to supergrowth when volume expansion resumes.

This study shows that PLEKHO1 in osteoblasts worsens joint inflammation in RA and promotes bone formation, suggesting it as a therapeutic target.

This study isolates and characterizes a wheat-specific phosphate-solubilizing Pseudomonas strain, showing its ability to colonize the wheat rhizosphere, enhance growth, and downregulate the phosphate transporter gene TaPT4.

This study generates transgenic pigs expressing microbial enzymes to enhance feed digestion and reduce nutrient emissions, showing improved growth and lower environmental impact.

This study shows that EPAC1 promotes ANXA2 translocation to endothelial cell surfaces, enhancing plasminogen to plasmin conversion and fibrinolysis.

The paper identifies and characterizes two genes, CsMYB6A and CsUGT72AM1, that promote flavonoid accumulation in purple-leaf tea, with CsMYB6A activating structural genes and CsUGT72AM1 catalyzing flavonol glycosylation.