X. Song

This study shows that human cord blood-derived stem cells suppress B-cell activation via a Gal-9-dependent cell contact mechanism and affect calcium levels and signaling pathways.

This paper develops a deep learning method to segment cellular ultrastructures in 3D EM images, achieving high accuracy for nuclei and nucleoli in cancer biopsies.

This study generates new cell lines for undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor to better study sarcomagenesis and develop therapies.

This paper develops a time-varying kinship model to analyze how changing demographic rates affect kinship structures over time.

The paper examines factors affecting maternal microchimerism (MMc) in infants and its impact on T cell immunity following BCG vaccination.

This study shows that gut microbiota in Anopheles stephensi affects tryptophan metabolism, with Pseudomonas alcaligenes reducing 3-HK to protect against Plasmodium infection.

This study shows R13, a TrkB agonist, improves mitochondrial function and reduces AD-related pathology in 5xFAD mice by enhancing biogenesis and metabolism.

This study identifies altered gene expression and cell interactions in oocytes and cumulus cells of PCOS patients, highlighting dysregulated microtubule genes and transposable elements.

This study investigates a fermented Yi traditional medicine, JB10, showing significant in vitro suppression of SARS-CoV-2 replication with EC50 of 769.1 dilutions and a selection index of 42.68.

The paper identifies a feedback loop between Astrin-PP1 and CyclinB-CDK1 that stabilizes mono-oriented chromosome-microtubule attachments independent of biorientation.

This study finds a significant association between Kaposi's Sarcoma Herpesvirus (KSHV) infection and osteosarcoma in the Xinjiang Uyghur population, identifying KSHV as a potential risk factor and a newly identified viral-associated cancer.

The study analyzes the urinary microbiota of 147 Chinese women, revealing non-sterile urine with distinct bacterial communities and showing similarity to cervical and uterine microbiota rather than vaginal microbiota.

This study examines how furfural residue amendments affect rhizosphere microbiota diversity and composition in long-term maize monocropping, showing increased beneficial microbes and reduced pathogens.

A mouse-adapted SARS-CoV-2 strain with RBD mutations caused 100% mortality in aged male BALB/c mice and showed altered receptor binding affinity.

This study establishes a mouse model of renal cell carcinoma showing that 9p21 loss drives aggressive tumor evolution with chromosomal instability and metastasis.

The paper identifies leukemia stemness and co-occurring mutations as drivers of resistance to IDH inhibitors in AML through genomic analyses of treated patients.

This study uses single-cell DNA sequencing to analyze clonal diversity in AML, revealing mutation co-occurrence, mutual exclusivity, and evolutionary patterns linked to treatment resistance and poor prognosis.

The paper investigates how temporal changes in functional traits and neighborhood crowding affect tree growth in a tropical forest, finding that dynamic factors better predict growth rates than static ones.

This study develops a model to characterize cell membrane mechanics using relaxation curves from optical tweezers, revealing insights into cell skeleton changes and protein diffusion.

This paper describes a phage that targets human glycans to enhance its activity in the gastrointestinal tract by positioning it near bacterial hosts.

The paper examines ACE2 expression on immune cells and finds that activated type 1 macrophages (M1) have high ACE2 expression, suggesting they may be targeted by SARS-CoV-2.

The paper develops a biparatopic antibody-ACE2 fusion (89C8-ACE2) that effectively blocks SARS-CoV-2 infection in vitro and neutralizes authentic virus at low nanomolar concentrations.

This study identifies potential mechanisms of celastrol's anti-inflammatory effects in rheumatoid arthritis by analyzing transcriptomic and proteomic changes in fibroblast-like synoviocytes.

This paper identifies a potent neutralizing antibody targeting the N-terminal domain of SARS-CoV-2 Spike protein, revealing it as a new therapeutic target.

The paper determines the crystal structure of the MBTD1-EPC1 complex, revealing the molecular mechanism of MBTD1 recruitment into the NuA4/TIP60 acetyltransferase complex.

This study shows rottlerin reduces DSS-induced colitis in mice by enhancing intestinal barrier function through the Epac-2/Rap-1 signaling pathway.

This paper presents a dataset of speed-resolved blood perfusion and oxygen saturation in human skin under thermal stimulation and control conditions.

This study shows that deletion of RgsA in Pseudomonas aeruginosa reduces growth and oxidative stress resistance in both planktonic and biofilm states.

This study evaluates a novel three-dimensional grid intrauterine device (3-DGIUD) in rhesus macaques, finding it effective for contraception without significant impact on endometrial steroid receptors and PAX2 expression.

The study investigates the impact of Bt-506 corn leaf litter on Collembola and decomposition rates, finding no significant effect of Bt protein but differences due to litter composition.