spatial domain detection

Torsion in motion: the visual system as a three-axis gimbal

This study estimates eye torsion during walking using head-mounted technology and shows its role in altering retinal flow for self-motion parameter extraction.

Distinct gradients of cortical architecture capture visual representations and behavior across the lifespan

The paper shows two architectural gradients in human visual cortex that correlate with structural, functional, and behavioral traits across the lifespan.

The Effects of Physical Exercise on Osteocyte Lacunar Morphology and Orientation around Bioresorbable Implants

This study examines how physical exercise affects osteocyte lacunar morphology and orientation around bioresorbable implants in rats, showing increased lacunar size and altered orientation with exercise.

Molecule-resolved inference reveals the spatial organization of transcriptional programs

The paper introduces FICTURE2, a statistical model that infers transcriptional programs from individual RNA molecules in spatial transcriptomics data, revealing spatial organization and cellular identity without segmentation.

Advect, retain, sense: cilia-driven vortices deliver symbiont bacteria and flowborne cues to a mucociliary olfactory organ

This study identifies the olfactory organ in bobtail squid as a site for detecting and retaining symbiotic bacteria through cilia-driven vortices, distinct from the light organ.

Tissue-specific transcriptomic responses to early Toxoplasma gondii infection in sheep during congenital toxoplasmosis

This study examines early transcriptomic responses to Toxoplasma gondii infection in pregnant sheep, identifying tissue-specific immune and stress pathways linked to fetal loss.

High-resolution temporal profiling reveals synchronized dynamics of the mouse gut microbiome

This study reveals synchronized temporal dynamics in the mouse gut microbiome using high-resolution sampling and analysis methods, showing phase-coherent groups linked to host circadian cycles.

Algorithmic Geometry Shapes the Biological Meaning of Thalamocortical Structural Covariance

The paper compares five algorithms for deriving structural covariance networks in the thalamocortical system and finds they emphasize different neurobiological aspects based on their mathematical properties.

Brain representations of visual short-term memories during healthy human aging: occipital decline and frontoparietal compensation

This study investigates age-related changes in visual short-term memory using fMRI decoding, finding that visual cortex representations weaken with age and load, while frontoparietal regions compensate by strengthening during memory maintenance.

Accumulation of FAM98B and tRNA-Splicing Ligase Complex Proteins in Neuronal Intranuclear Inclusions in Spinocerebellar ataxia type 4.

The paper examines the localization of tRNA-splicing ligase complex proteins in SCA4 pontine neurons, finding their accumulation in neuronal intranuclear inclusions.

Osmotic Coupling of Mechanics and Epigenetics Regulates Chromatin Phase Organization

This study develops a model linking nuclear hydration to chromatin phase organization and mechanics, showing how osmotic and mechanical cues influence chromatin structure through water content and histone dynamics.

Hexagonal modulation of theta rhythmic attentional sampling of visual space

The paper shows that visual attention samples space in a hexagonal pattern guided by theta rhythms, similar to spatial navigation mechanisms.

A CTCF-LDHB axis converts nuclear lactate availability into an H3K18 acylation switch that directs alternative splicing in hypoxic breast cancer

Development of auxin reporters in oilseed rape (Brassica napus)

This study develops auxin reporters for oilseed rape to visualize and quantify auxin distribution and signaling during development and stress.

Spatial Landscape of Pregnancy-Associated Triple Negative Breast Cancer and Mammary Gland Involution

This study compares transcriptional differences between pre- and post-involution PA-TNBC tissues using spatial transcriptomics, identifying distinct inflammatory and chromatin remodeling patterns in post-involution tumors.

In Utero MRI of Radial Glial Fibers Highlights Their Role in Modulating Fetal Cortical Folding

This study uses in utero MRI and computational models to show that radial glial fibers influence fetal cortical folding through biomechanical modulation.

Revealing multiscale architecture of the intact human spine using hierarchical phase contrast tomography

This paper uses HiP-CT to image the human spine at high resolution, revealing multiscale anatomy and microstructural features without exogenous contrast.

Two closely related RNA helicases, UAP56 and URH49, couple mRNA splicing and export pathways with their distinct complexes

This study identifies three splicing regulation patterns mediated by UAP56 and URH49 and their association with mRNA export pathways.

Distributed brain-spinal cord dynamics during micturition revealed by functional ultrasound imaging

This study uses functional ultrasound imaging to map brain and spinal cord activity during micturition in rats, revealing region-specific hemodynamic responses and decoding bladder pressure dynamics.

Spatialsnake: a flexible workflow for spatial transcriptomics analysis across platforms

Spatialsnake provides a flexible workflow for spatial transcriptomics analysis across multiple platforms, enabling analysis of selected populations and tissue regions with adjustable parameters.

Metabolic and transcriptional responses reveal co-option of symbiotic processes during early soybean-soybean cyst nematode interaction

This study identifies metabolic and transcriptional changes in soybean during soybean cyst nematode infection, revealing immune system remodeling and co-option of symbiotic processes.

Dose-dependent transcriptional responses of marine prokaryotes to Fe-rich colloids of glacial and non-glacial origin in the Kerguelen region (Southern Ocean)

This study examines how marine prokaryotes respond transcriptionally to Fe-rich colloids from glacial and non-glacial sources, revealing contrasting growth and metabolic responses.

Gene context shapes spatial organization and transcriptional heterogeneity of extrachromosomal DNA in cancer cells

This study investigates how gene context influences the spatial organization and transcriptional behavior of extrachromosomal DNA in cancer cells using a new imaging method called FLAGx.

Nucleotide-resolution Mapping of RNA N6-Methyladenosine (m6A) modifications and comprehensive analysis of global polyadenylation events in mRNA 3' end processing in malaria pathogen Plasmodium falciparum

The paper maps m6A modifications and polyadenylation events in Plasmodium falciparum mRNAs, identifying stage-specific m6A sites and their potential role in 3' end processing.

Multi-region recordings reveal collapse of hippocampal CA3-amygdala gamma communication at seizure onset in mice

The paper uses multi-region recordings in mice to show that gamma communication between hippocampal CA3 and amygdala collapses abruptly at seizure onset.

A new neural code for position: generalizable spatial maps in mouse medial frontal cortex

The paper identifies a novel neural code in the mouse medial frontal cortex that supports spatial generalization through extrapolation of coordinates across regions.

Charting vulnerability of brainstem functional pathways in aging and prodromal synucleinopathy

This study maps brainstem-cortical connectivity in aging and prodromal synucleinopathy, finding distinct pathway vulnerabilities in each condition.

Glutamatergic excitation suppresses latent cortical pacemaking

The paper shows that reducing glutamatergic excitation in the awake rabbit cortex reveals a local population pacemaker mechanism, distinguishable from epileptiform activity.

The global distribution of human-visible flower color diversity

The paper analyzes global flower color diversity using community science data, finding a latitudinal gradient in color diversity and associations with climate and pollination strategies.

Multi-scale spatial transcriptomic atlas of the whole mouse spinal cord

The paper creates a spatial transcriptomic atlas of the whole mouse spinal cord, revealing multi-scale cellular organization and gene-expression patterns across different regions.