Olfactory and Sensory Function Studies

Natural and pathological aging distinctively impact the vomeronasal system and social behavior

This study shows that natural and pathological aging differently affect the vomeronasal system and social behavior in mice.

Slow gamma oscillations in the mouse olfactory bulb are correlated with sniffing in the dark period

The paper examines how LFP oscillations in the mouse olfactory bulb correlate with sniffing during dark and light periods, finding stronger correlations in the dark.

Metabolic activity organizes olfactory representations

The paper identifies a molecular-level representation of odors that predicts receptor, neural, and behavioral responses across species and shows metabolic relationships in odor space.

Quantifying peripheral modulation of olfaction by trigeminal agonists

This study quantifies how trigeminal agonists modulate olfactory responses by measuring Ca2+ changes and EOG responses in mice, showing that trigeminal activation reduces olfactory signal strength.

Exploring the vomeronasal organ in an endangered antelope species

This study examines the vomeronasal organ in dama gazelles to assess its structure and function, contributing to understanding semiochemical communication and reproductive biology.

A conserved role for stomatin domain genes in olfactory behavior

This study identifies a shared role for mec-2 and Stoml3 in olfactory behavior across C. elegans and mice, showing that they are required for odor discrimination but not odor detection.

Odor imagery but not perception drives risk for food cue reactivity and increased adiposity

The paper investigates how odor imagery, not perception, influences food cue reactivity and adiposity in healthy individuals.

Arc-Expressing Accessory Olfactory Bulb Interneurons Support Chemosensory Social Behavioral Plasticity

This study identifies Arc-expressing interneurons in the accessory olfactory bulb that contribute to chemosensory social behavior plasticity through increased excitability and chemogenetic manipulation.

Expansive Linguistic Representations to Predict Interpretable Odor Mixture Discriminability

The paper uses semantic descriptors from language to predict odor mixture discriminability, outperforming existing methods by leveraging human perception data.

Screening and identification of two pheromone receptors based on the coadaptation of pheromones and their receptors in rats

The paper identifies two pheromone receptors in rats based on coadaptation with their respective pheromones, showing coevolution between pheromones and receptors.

EEG Changes during Odor Perception and Discrimination

This study investigates EEG changes during odor perception and discrimination, finding that frontal theta rhythms reflect odor processing and could be used in olfactory-based BCIs.

EEG correlates of olfactory processing during an instructed-delay task

This study identifies EEG correlates of olfactory processing during an instructed-delay task, finding specific spatio-spectral patterns associated with odor processing.

Long-range GABAergic projections contribute to cortical feedback control of sensory processing.

The paper identifies long-range GABAergic inhibitory feedback from cortical areas to the olfactory bulb, showing its role in modulating sensory processing and odor discrimination.

FIRST INSIGHTS IN A NON-RODENT MODEL SPECIES OF THE OLFACTORY LIMBUS. THE RED FOX (Vulpes vulpes) AS A CASE IN POINT

The paper studies the olfactory limbus in red foxes, finding it highly developed and complex, suggesting its value as a model for non-canonical chemosensory processing.

Structural spine plasticity: learning and forgetting of odor-specific subnetworks in the olfactory bulb

The paper presents a computational model of structural plasticity in the olfactory bulb that explains odor-specific subnetwork formation and differential learning effects during odor exposure.

Sex separation unveils the functional plasticity of the vomeronasal organ in rabbits

This study examines how sex separation affects gene expression in the rabbit vomeronasal organ, revealing sex- and stage-specific plasticity in response to environmental changes.

Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb

The paper shows immature olfactory sensory neurons provide distinct odor input to the olfactory bulb, contributing to odor detection and discrimination tasks.

Sniffing response to an odor through development in rats: modulatory role of repetition and association with an aversive event

This study examines how sniffing responses to odors develop in rats, showing age-related differences in habituation and fear conditioning.

Wiring logic of the early rodent olfactory system revealed by high-throughput sequencing of single neuron projections

The paper uses high-throughput sequencing to analyze neuronal projections in the mouse olfactory system and finds structured connectivity along the anterior-posterior axis.

A non-canonical feedforward pathway for computing odor identity

The paper identifies a non-canonical feedforward pathway for odor recognition mediated by tufted cells in the olfactory bulb, challenging the traditional role of the piriform cortex.

Neural representation of intraoral olfactory and gustatory signals by the mediodorsal thalamus in alert rats

This study shows that mediodorsal thalamus neurons in alert rats dynamically encode intraoral olfactory and gustatory signals, including odor-taste mixtures and taste palatability.

Pseudotime analysis reveals novel regulatory factors for multigenic onset and monogenic transition of odorant receptor expression

The paper uses pseudotime analysis of single-cell RNA-Seq data to identify regulatory factors involved in the transition from multigenic to monogenic odorant receptor expression in mouse olfactory neurons.

Human olfactory neuronal cells through nasal biopsy: molecular characterization and utility in brain science

This study characterizes olfactory neuronal cells from nasal biopsies using single-cell and bulk RNA sequencing, showing their neuronal similarity and utility in brain disorder research.

Sociosexual behavior requires both activating and repressive roles of Tfap2e/AP-2ε in vomeronasal sensory neurons

The paper shows that AP-2ε reprograms vomeronasal sensory neurons and their behaviors by controlling gene expression, bypassing cellular plasticity restrictions.

Uncertainty revealed by delayed responses during olfactory matching

This study develops an automated olfactory matching paradigm to assess sensory and cognitive functions in humans, finding that accuracy and decision times correlate with perceptual certainty and odor complexity.

Pyrfume: A Window to the World's Olfactory Data

Pyrfume provides a unified framework to access and analyze diverse olfactory datasets across species and modalities, enabling novel analyses and benchmarks for machine olfaction.

Learning-dependent evolution of odor mixture representations in piriform cortex

This study shows how mice's piriform cortex neurons adapt to learn and distinguish odor mixtures, becoming more selective over time and improving population-level categorization.

The olfactory bulb carries out concentration invariance calculations by itself and does it very quickly.

The paper shows that the olfactory bulb performs concentration invariance computations independently and rapidly without relying on feedback from other brain regions.

A Genetic Platform for Functionally Profiling Odorant Receptors Ex Vivo Using Olfactory Cilia.

The paper describes an ex vivo platform using olfactory cilia to functionally profile human odorant receptors with high sensitivity and scalability.

Phenotype-driven identification of drug targets for post-COVID-19 anosmia

This paper identifies six potential drug targets for post-COVID-19 anosmia using a phenotype-to-gene-to-drug approach via the Phenograph knowledge graph.