melanin and skin pigmentation

Generation of a white-albino phenotype from cobalt blue and yellow-albino trouts: inheritance pattern and chromatophores analysis

The paper investigates the inheritance pattern and chromatophore distribution in cobalt blue and white-albino trouts, identifying a new phenotype and linking it to pituitary gland abnormalities.

Identification of kit-ligand a as the Gene Responsible for the Medaka Pigment Cell Mutant few melanophore

The paper identifies kit-ligand a as the gene responsible for the medaka pigment cell mutant few melanophore and shows its role in pigment cell specification.

Combined Transcriptomics and Proteomics Forecast Analysis for Potential Genes Regulating the Columbian Plumage Color in Chickens

This study identifies differentially expressed genes and proteins in chicken feather follicles associated with Columbian plumage coloration using transcriptomic and proteomic analyses.

Effects of mutations in pigeon Mc1r implicate an expanded plumage color patterning regulatory network

The paper identifies a frameshifting deletion in pigeon Mc1r linked to a recessive pigmentation trait and shows that Mc1r loss increases eumelanism without pheomelanism, suggesting Mc1r-independent pathways in birds.

Nested tandem duplications of the gene Melanoma antigen recognized by T-cells (Mlana) underlie the sexual dimorphism locus in domestic pigeons

The paper identifies a large tandem duplication in the Mlana gene associated with the Stipper locus in domestic pigeons, contributing to sexual dimorphism.

GABA-A signaling maintains melanocyte stem cell quiescence in larval zebrafish

The paper identifies GABA-A rho signaling as essential for maintaining quiescence of melanocyte stem cells in larval zebrafish and preventing excessive pigmentation.

Fate plasticity and reprogramming in genetically distinct populations of Danio leucophores

The paper identifies two distinct leucophore populations in zebrafish, showing their different origins and functional roles through single-cell transcriptomics and other analyses.

Slc7a11 modulated by POU2F1 is involved in pigmentation in rabbit

This study identifies Slc7a11's role in rabbit pigmentation and shows that POU2F1 regulates its expression to influence melanogenesis and apoptosis.

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish

The paper identifies Endothelin receptor Aa as a regulator of APSC quiescence in zebrafish, linking blood vessel signals to pigment cell differentiation.

The genetic architecture of hair colour in the UK population

The paper maps the genetic architecture of hair colour in the UK population, identifying multiple loci and epistatic interactions contributing to red and blonde hair.

Evolution of Endothelin signaling and diversification of adult pigment pattern in Danio fishes

The paper identifies Endothelin-3 as a factor contributing to differences in iridophore development and pigment patterns between Danio rerio and D. nigrofasciatus.

Melanin pathway genes regulate color and morphology of butterfly wing scales

This study shows that melanin pathway genes influence butterfly wing scale morphology and coloration through structural changes in cuticular laminae.

Tissue-specific Gene Expression Prediction Associates Vitiligo with SUOX through an Active Enhancer

The paper identifies SUOX as a vitiligo-associated gene by integrating GWAS data with tissue-specific gene expression prediction and experimental validation of an enhancer.

CREBBP and WDR 24 Affects Quantitative Variation in Red Colouration in the Chicken

The paper identifies five candidate genes affecting quantitative red colouration variation in chickens using QTL mapping and genetical genomics.

Increased PHGDH expression uncouples hair follicle cycle progression and promotes inappropriate melanin accumulation

This study shows that increased PHGDH expression in mice leads to premature melanin accumulation in hair follicles, suggesting a role for PHGDH in melanocyte biology and potential involvement in melanoma.

Widespread dynamic and pleiotropic expression of the melanocortin-1-receptor (MC1R) system is conserved across chick, mouse and human embryonic development

The paper shows MC1R is widely expressed in non-cutaneous tissues during embryonic development across chick, mouse, and human, with potential pleiotropic effects on birthweight.

An Unexpectedly Complex Architecture for Skin Pigmentation in Africans

The paper shows that skin pigmentation in African populations, particularly the KhoeSan, is highly heritable and polygenic, with many new genetic loci identified beyond previously known ones.

Genetic basis of melanin pigmentation in butterfly wings

The paper identifies genes involved in butterfly wing pigmentation through RNA-seq and CRISPR/Cas9, revealing localized effects of melanin pathway genes on color patterns.

Association of five SNPs with human hair colour in the Polish population

The paper identifies five SNPs associated with hair color in a Polish population and shows that including rs1800401:C>T in OCA2 improves prediction accuracy.

Comparative transcriptome analysis by deep RNA sequencing at early stage of skin pigmentation in goats (Capra hircus)

The paper uses RNA sequencing to compare gene expression in dark- and white-skinned goats during early skin pigmentation, identifying differentially expressed genes and novel transcripts related to melanogenesis.