Cardiovascular and exercise physiology

High Intensity Interval Training in Aged Female Mice Preserves Physical, Cognitive, and Cardiovascular Function

This study shows that high intensity interval training (HIIT) preserves physical, cognitive, and cardiovascular function in older female mice and reduces frailty.

Low-load blood flow restriction training and ischemia modulate expression of Na+,K+-ATPase and FXYDs in human skeletal muscle

This study examines how low-load blood flow restriction training and ischemia affect Na+,K+-ATPase and FXYD expression in human skeletal muscle after ACL injury.

A Doppler Ultrasound Method to Measure Vascular Responses to Walking

This study demonstrates a Doppler ultrasound method to measure vascular responses to walking, showing increased leg blood flow during uphill walking.

Mitochondrial cristae density is increased following high-intensity interval training in patients with type 2 diabetes

This study finds that high-intensity interval training increases mitochondrial cristae density in type 2 diabetes patients, with no baseline differences in cristae density compared to other groups.

RACLET: the Ramp Above Critical Level Endurance Test to evaluate critical force in isometric task.

RACLET evaluates critical force parameters without strenuous exercise, showing high reliability and validity in healthy and respiratory patient populations.

Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults

This study finds that higher cardiorespiratory fitness in older adults is linked to increased cerebral blood flow and decreased oxygen extraction fraction.

Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation

SAAR improves exercise capacity in mice by enhancing fat oxidation and substrate availability through VEGF signaling and CD36-dependent fatty acid transport.

Effects of High-Intensity Interval Training on Physical and Cognitive Function in Middle-Aged Male Mice

This study examines the effects of three months of high-intensity interval training on physical and cognitive function in middle-aged male mice, finding improved aerobic capacity but no significant cognitive benefits.

MicroRNA signatures of VO2peak in older adult participants of the Study of Muscle, Mobility and Aging

The paper identifies miRNA signatures associated with VO2peak variation in older adults using serum small RNA sequencing and statistical analysis.

Shared and distinct adaptations to early-life exercise training based on inborn fitness

This study shows early-life exercise training can mitigate low inborn cardiorespiratory fitness effects, but molecular adaptations vary based on innate fitness.

Leg immobilization and subsequent recovery resistance training affect skeletal muscle angiogenesis related markers in young healthy adults regardless of prior resistance training experience

This study examines how leg immobilization and recovery resistance training affect skeletal muscle angiogenesis markers in young adults, finding similar molecular responses regardless of prior training experience.

Sex differences in the cardiopulmonary and neuromuscular response to high-intensity interval exercise

This study examines sex differences in cardiopulmonary and neuromuscular responses to high-intensity interval exercise, finding greater hyperpnoea in females during early intervals and lesser decreases in contractile function post-exercise.

E-bike riding: A metabolic evaluation in the context of exercise intensity domains

This study evaluates the metabolic demand of e-bike riding at different intensities and finds that e-bike assistance reduces metabolic demand below the threshold for cardiorespiratory benefits.

Increased cGMP improves microvascular exercise training adaptations independent of endothelial nitric oxide synthase

This study shows that sildenafil enhances microvascular adaptations to exercise training in obese mice, independent of endothelial nitric oxide synthase function.

Estimating intra-subject and inter-subject oxygen consumption in outdoor human gait using multiple neural network approaches

This paper estimates oxygen consumption during outdoor human gait using neural networks, finding that XceptionNet outperforms LSTM for inter-subject estimation.

Hippocampal blood flow rapidly and preferentially increases after a bout of moderate-intensity exercise in older adults with poor cerebrovascular health

This study examines the acute cerebral blood flow response to moderate-intensity exercise in older adults, finding a rapid hippocampal-specific increase in blood flow in those with poor baseline perfusion.

The complex relationship between effort and heart rate: a hint from dynamical analysis

The paper improves a heart rate model during exercise by incorporating power-dependent gain, showing high predictive accuracy and linking metabolic changes to heart rate dynamics.

Validity of dynamical analysis to characterize heart rate and oxygen consumption during effort tests

This study evaluates dynamical analysis of heart rate and oxygen consumption during effort tests to characterize physical performance, finding that gain metrics are robust and informative.