A. Liu

This study examines gut microbiota composition in GDM patients before and after diet intervention, finding that diet affects the Firmicutes/Bacteroidetes ratio and specific taxa rather than altering the overall microbial pattern.

The paper introduces a 4D subtractive manufacturing technique to create perfusable complex tissues in multi-well plates, enabling the fabrication of vascular networks and organ-specific structures.

The paper identifies LCS3, a compound that induces oxidative stress in lung cancer cells by inhibiting disulfide reductases GSR and TXNRD1, and shows its synergistic effect with glutathione and thioredoxin pathway inhibition.

This study shows autophosphorylation of small GTPases like H-RAS and K-RAS alters their nucleotide exchange and effector interactions, changing their functional behavior.

The paper investigates the role of BASL in Arabidopsis stomatal lineage asymmetric cell divisions, showing distinct functions before and after division in regulating cell size and fate.

The paper identifies scaling relationships between genes in cancer data, finding LMNB1 correlates with poor prognosis while fibrosis markers predict better survival.

The paper evaluates the cytotoxicity and efficacy of five antiseptics in an ex vivo human wound model, finding chlorhexidine gluconate reduces microbial counts but harms tissue viability.

This study identifies the ERK-CBP/p300-ETS axis as promoting lineage transformation between neuroendocrine and non-neuroendocrine lung cancer subtypes through chromatin rewiring.

The paper introduces a generative model to test hypotheses about cell-cell interactions in tumor microenvironments using synthetic multiplexed images.

This study identifies N4BP1 as an inhibitor of NF-κB activation by interacting with NEMO, and shows that caspase 8 cleavage inactivates N4BP1 during TRIF-dependent signaling.

The paper introduces Deep-LUMEN, a deep learning algorithm for classifying lung epithelial spheroids from brightfield images, and validates its ability to detect morphological changes in response to drug treatments.

The paper identifies 200 approved drugs that target SARS-CoV-2-induced pathways, with 40 in clinical trials, and classifies them into viral replication and immune response mechanisms.

This study develops an ex vivo human skin model to simulate contact burns and assesses inter-individual variability in tissue injury and healing over time.

This study identifies distinct B cell signatures and tertiary lymphoid structures in HPV+ and HPV- HNSCC, highlighting their role in antitumor immunity.

This study shows that Hoogsteen base pairs in dsDNA increase susceptibility to methylation damage, challenging the assumption that Watson-Crick faces are fully protected.

This paper demonstrates a tunable ultrafast stroboscopic TEM system that reduces radiation damage in macromolecules by increasing critical dose at room temperature.

This study shows that ATP released by Candida albicans activates non-peptidergic neurons to enhance anti-Candida immune responses.

This study characterizes treatment-induced high-grade gliomas (TIHGGs) through molecular profiling, identifying distinct subgroups and potential therapeutic targets.

This study shows that rats represent 3D space using place cells, with activity aligned to maze axes and reduced accuracy when vertical movement is difficult.

This study identifies 53 QTLs associated with Verticillium wilt resistance in cotton using CSSLs and detects 32 novel QTL hotspot regions, providing a foundation for genetic analysis and breeding programs.

The paper identifies a methyltransferase responsible for S-methylcysteine modification in MCR and shows that interactions between post-translational modifications affect enzyme function and thermal stability.

This study uses solvent extraction combined with indigenous microbial degradation to remediate oil-contaminated soil, showing improved soil quality and plant growth.

The paper introduces a theoretical model to predict nanoparticle membrane permeation time by separating nanoparticle and membrane properties, validated with experimental and simulation data.

This study uses spatial point process analysis to show that neutral processes, not niche processes, dominated the spatial distribution of Ediacaran animal communities.