D. Zhang

The paper introduces VHUT-cryo-FIB, a workflow for preparing frozen-hydrated tissue lamella for cryo-ET, and demonstrates its effectiveness using rat and spinach samples.

This study examines how melatonin affects wheat seed germination and amino acid content under PEG stress, finding that 300 μM melatonin improves germination metrics and lysine levels.

The paper uses solid-state NMR to study a constitutively open mutant of KcsA, finding reduced potassium binding affinity at the selectivity filter, supporting allosteric coupling in C-type inactivation.

The paper identifies intron retention as a hallmark of aggressive prostate cancer and highlights the spliceosome as a therapeutic target by analyzing splicing dysregulation across prostate cancer progression.

The paper uses cryo-EM to study SOPA1's structure and conformational changes upon GTP binding, revealing its unique mechanism in mitochondrial membrane fusion.

This study identifies the catalytic core of DME as essential for active DNA demethylation in Arabidopsis, showing that the N-terminus is required for heterochromatin demethylation and specificity.

This study uses single-cell RNA-seq to analyze human infant retina, identifying cell types, communication networks, and developmental changes, providing a resource for retinal research and regenerative medicine.

The paper identifies genes involved in DNA damage response and translation that influence susceptibility to TOP2 poisons in gliomas and other cancers.

This study characterizes the colonization dynamics of Rhodopseudomonas palustris GJ-22 on tobacco phyllosphere and shows it induces plant resistance to Tobacco mosaic virus.

This study uses single-cell RNA sequencing to analyze the cellular diversity and molecular markers in the retina of a trisomy 21 fetus, revealing communication networks and novel markers.

This study investigates the localization and role of CK2 in Magnaporthe oryzae during growth and infection, finding it localizes to nuclei, nucleoli, septal pores, and appressoria with regulatory functions.

The paper investigates how mitochondrial architecture rearrangements in Isopoda cause asymmetrical mutational pressures, leading to unreliable phylogenetic reconstructions and supports Asellota as the basal isopod branch.

The paper identifies four polyploidy events in the evolutionary history of Physcomitrella patens, including two ancient duplications and one associated with Bryopsida diversification.

This study shows that fasting reduces circulating pro-inflammatory monocytes and their metabolic activity, while preserving their emergency mobilization during acute inflammation.

The paper introduces TmDOTP, an NMR thermometer for monitoring temperature in solid-state NMR experiments, showing it provides higher thermal sensitivity and resolution than traditional methods.

This study examines how food restriction affects tree shrews' body mass, energy metabolism, and thermogenesis under different temperatures and food intake levels.

This study identifies risk and protective factors for dengue virus infection in Guangdong Province through a case-control study, finding activities in the park, outdoor sports, and poor indoor daylight quality as risk factors, and air-condition use as protective.

This paper introduces a multimodal interferometric imaging platform to study nanoscale structure and macromolecular dynamics in live cells, revealing a new phenomenon called cellular paroxysm induced by UV light.

This study evaluates how well fecal samples represent chicken gut microbiota, finding that feces can identify most taxa but not fully capture microbial community structure.

The paper identifies and maps the stripe rust resistance gene YrTZ2 in wild emmer wheat and compares its genomic region with Aegilops tauschii.

This study shows autophagy promotes osimertinib resistance in EGFR-mutant lung cancer by enhancing stem-cell like properties, and inhibiting autophagy reverses resistance.

The paper identifies BAM1 as a positive regulator of RNAi cell-to-cell spread and shows that a viral protein inhibits this process by interacting with BAM1 and BAM2.

The paper uses genome-wide SNPs to analyze gene flow in Ae. albopictus, finding that distance from shipping terminals and isolation by distance drive genetic structure.

The paper introduces DropSynth, a method for multiplexed gene synthesis in emulsions to explore protein functional landscapes by synthesizing and testing phylogenetically diverse orthologs.

The paper predicts DNA hybridization rate constants from sequence using a weighted neighbor voting model trained on experimental kinetics data.

This study shows Mcm10 enables CMG helicase to bypass DNA blocks on the non-tracking strand by isomerizing the CMG-DNA complex.