F. Liu

This study identifies endogenous protein pyrophosphorylation in human cell lines using a tailored pyrophosphoproteomics workflow, revealing its role in rDNA transcription regulation.

This study identifies inter-holoenzyme phosphorylation as the mechanism for spreading CaMKII activity, challenging the subunit exchange hypothesis.

This study shows that Ena/VASP proteins are essential for dendritic cell migration by coordinating actin nucleation pathways through interactions with formin mDia1 and the WAVE complex.

This study uses a genome-wide CRISPR/Cas9 screen to identify regulators of dendritic cell differentiation in a Flt3L-dependent murine progenitor cell line.

The paper identifies a new endolysosome process, LEA, where autophagosomes are engulfed by extending arms (LF) without fusion, and describes the molecular markers of engulfed autophagosomes.

The paper maps spatial and functional interactions between virus and host proteins in intact cytomegalovirus particles using cross-linking mass spectrometry and proteomics.

This paper introduces a novel framework using unrolled optimization neural networks to improve EEG/MEG source imaging by learning source patterns data-driven, achieving better performance than traditional methods.

This study identifies amino acids in wheat NLRs Sr33 and Sr50 that mediate effector recognition and autoactivity, enabling engineered resistance.

This study examines how chronic intermittent hypoxia and chronic sleep fragmentation affect gut microbiota, serum metabolites, and tissue morphology in mice, revealing their impact on lipid metabolism.

This study examines the bladder microbiome, metabolome, and cytokines in SLE patients, finding associations between microbial composition and disease-related metabolites and cytokines.

The paper identifies GauERF105 as a key gene involved in cotton resistance to Verticillium wilt through transcriptome analysis and functional validation.

This study develops an enzyme-based method to extract plant extracellular vesicles, showing higher yield and therapeutic potential compared to traditional methods.

This study identifies ADAP's intrinsically disordered region as an actin sponge that regulates T cell motility by promoting actin polymerization and bundling.

This paper proposes Anes-MetaNet, a meta-learning based deep learning model to classify brain states under anesthesia using EEG data, showing improved performance over existing methods.

This study uses phylogenomic analysis of Alismatales to investigate adaptations to aquatic environments and identify whole-genome duplication events.

This study uses RNA-seq to identify molecular changes in kidney cancer among people living with HIV, finding altered expression of specific genes and pathways associated with cancer progression.

This study compares alpha-synuclein fibril structures from preclinical and postmortem Parkinson's disease patients, showing structural and pathological differences in fibril conformation during disease progression.

This study uses spatial transcriptomics to analyze invasive fronts in solid tumors, identifying immune cell enrichment, metabolic changes, and poor prognosis factors.

This study identifies a signaling pathway involving CNP, NPR2, PKG, BK channels, and TRPM7 that facilitates Ca2+ entry in growth plate chondrocytes to stimulate bone growth.

This study develops a high-throughput method to produce functional prototissues that generate nitric oxide, inducing vasodilation in rat blood vessels.

This paper engineers, decodes, and characterizes chimpanzee cytomegalovirus (CCMV) to explore its potential as a model for human CMV, identifying novel genes, regulatory elements, and functional roles.

This study identifies LENG8 as an mRNA processing factor that regulates mitochondrial activity by controlling mRNA nuclear export and mitochondrial protein expression.

The paper identifies a lethal mitonuclear incompatibility in swordtail fish hybrids involving three Complex I genes, showing non-additive genetic effects and inter-species transfer of incompatibility.

This study reconstitutes the DTX3L-PARP9 complex to identify determinants for high-affinity heterodimer formation and enzymatic function.

This study examines how nitrification inhibitors and straw incorporation affect N2O emissions and microbial communities in different cropland soils, finding that their effects vary by soil type.

This study identifies three ultrapotent SARS-CoV-2 neutralizing antibodies effective against B.1.351 variants, showing synergistic effects and protective efficacy in mice.

This study investigates how PAPD5 and PAPD7 stabilize HBV RNA and shows that PAPD5 is dominant in protecting the poly(A) tail, while PAPD7 acts as a backup mechanism.

This study identifies NPR1 and EDS1 as interacting coactivators that synergistically activate PR genes and plant defenses through Mediator complex recruitment and mutual stabilization.

REAP identifies autoantibodies targeting the human exoproteome by screening patient samples against a yeast-displayed extracellular protein library, revealing known and novel reactivities in autoimmune diseases.

Under constant infection by Sclerotinia sclerotiorum, BnaA03.WRKY28 interacts with BnaA09.VQ12 and takes precedence over phosphorylated BnWRKY33 to bind to the BnWRKY33 promoter, thereby weakening resistance but promoting branching.