G. Li

This paper introduces a self-blinking DNA probe for 3D superresolution imaging of native chromatin in live cells, revealing chromatin organization and decompaction dynamics.

The paper identifies incomplete lineage sorting in Sulfitobacter, a marine bacterium, showing rapid speciation driven by ancestral polymorphism retention rather than adaptive selection.

This study assembled the chromosome-level genome of Rorippa aquatica to investigate its allotetraploid origin and the molecular mechanisms of heterophylly under submergence.

This study shows that CTRP3 reduces intestinal inflammation in colitis models and IBD patients by modulating SIRT1/NF-κB signaling to suppress pro-inflammatory cytokines.

This study identifies CiS40-11 and its orthologs AtS40-5 and AtS40-6 as regulators of leaf senescence that promote cytokinin synthesis by inhibiting MYB2 expression.

This study compares the effects of immunomodulatory BT peptide and antibiotics on cecal microbiota in broilers challenged with Clostridium perfringens, finding differences in microbial composition and function.

This study shows that blocking the sympathetic nervous system reduces fasting-induced liver fat accumulation by suppressing CD36 upregulation.

This paper identifies a novel intergeneric recombinant geminivirus as the cause of soybean stay-green disease, showing it induces symptoms and can be detected in seed coats but not seeds.

This study identifies alkaloids and related intermediates in Dendrobium officinale using SPE-HPLC-LTQ-Orbitrap and database alignment.

This study uses single-nuclei transcriptomics to analyze dog hippocampus cell types and identifies convergence between differentially expressed genes and putative positively selected genes related to nervous system development.

This study shows that palatal morphology in early salamanders reflects ecological preferences and life history strategies, with significant evolutionary changes before the Middle Jurassic.

The paper determines the asymmetric homodimer structure of mouse pendrin using cryo-EM, revealing its electroneutral anion exchange mechanism and pathogenetic mutation properties.

This study presents three amphioxus reference genomes, revealing insights into chordate gene and chromosome evolution, including WGDs, chromatin architecture, and sex chromosome dynamics.

This study optimizes excitation wavelength and emission window for SPNs to improve imaging quality, showing L1057 NPs achieve superior resolution and signal-to-background ratio in the NIR-IIb window.

This study compares the effects of Cr(III) and Cr(VI) stress on Arabidopsis thaliana, showing Cr(VI) is more toxic due to greater growth inhibition, oxidative stress, and chloroplast damage.

This study investigates how DNA methylation in transposable elements disrupts the link between 3D chromatin organization and gene expression in rice after genome duplication.

This study shows that Ser68 phosphorylation is essential for CENP-A deposition, centromere function, and mouse viability.

This study shows that cholesterol and sphingomyelin in lipid rafts are essential for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages.

This study identifies plant genetic loci associated with rhizobiome composition in maize and shows host selection influences microbial abundance under different nitrogen conditions.

This study shows that autophagy-dependent TOR reactivation via α-ketoglutarate sustains fungal biotrophic growth in host rice cells.

The paper develops a screening pipeline to identify bile acid converting bacteria with anti-C. difficile properties, isolating Peptacetobacter hiranonis with unique biotherapeutic potential.

This paper identifies a monoclonal antibody, 2G1, that neutralizes all SARS-CoV-2 variants with high potency and describes its mechanism of action and therapeutic efficacy in animal models.

This study shows YY1 forms phase-separated super-enhancers by compartmentalizing coactivators and enhancer elements, with a histidine cluster essential for this process.

The paper analyzes SARS-CoV-2 sequences from minks and humans to determine if adaptive evolution occurred before the pandemic, suggesting the virus may have circulated in humans for at least six months prior to the Wuhan outbreak.

This study uses single-cell sequencing to analyze immune responses in acute Kawasaki disease before and after treatment, identifying key gene expression changes and immune cell dynamics.

This study shows that SARS-CoV-2 ORF7 increases monocyte chemotaxis via CCL2 and decreases neutrophil recruitment via reduced IL-8.

The paper uses computational methods to predict miRNA-target regulatory modules in soybeans under abiotic stress and identifies stress-related modules with gene ontology enrichment.

The paper identifies distinct extracellular tRNA-derived small RNA (tDR) fragmentation signatures associated with different stress responses and shows their potential as biomarkers in human disease.

This study identifies a miRNA biomarker signature combining plasma extracellular vesicle and circulating miRNAs to improve NSCLC diagnosis and predict resistance to Osimertinib.