G. Li

This study uses control-theoretic principles to optimize phage cocktail timing and composition for bacterial infection treatment, showing that two-phage cocktails can restore efficacy in immunodeficient hosts.

This study examines the overwintering behavior and cold hardiness of the purple stem borer in its newly colonized northern range, identifying its survival strategies and potential distribution limits.

This study uses RNA sequencing to analyze the transcriptomic changes in the inferior colliculus of mice after acute hydrogen sulfide exposure, identifying dysregulated pathways and neuroinflammatory responses.

This study investigates how temperature affects microtubule dynamics in budding yeast, finding that tubulin recycling limits cold tolerance and that disrupting this process can improve cold resistance.

This study shows that transient Dux overexpression improves SCNT and chemical reprogramming efficiency, while Dppa2/4 do not, and Dux treatment makes SCNT embryos resemble fertilized embryos.

The paper uses integrated proteomic and metabolic single-cell assays to identify two distinct adaptive pathways in BRAF-mutant melanoma cells during drug treatment.

The paper investigates how fish larvae generate effective swimming motions using simple actuation patterns despite complex fluid-structure interactions.

This study develops an efficient CRISPR/Cas9 method for integrating a large transgene cassette into the CEP112 locus in pigs, achieving successful expression of microbial enzymes in salivary glands.

This study shows engineered dendritic cells expressing multiple T cell inhibitory ligands induce CD4+ T cell tolerance and suppress autoimmunity.

This study identifies non-sedating benzodiazepines that cause contractile paralysis and tissue damage in Schistosoma mansoni, offering potential for new anti-schistosomal drugs with reduced host side effects.

This study isolates and identifies actinomycetes from soil samples in southwestern China, revealing high diversity and antimicrobial potential.

This study shows STING activates the NLRP3 inflammasome by recruiting NLRP3 to the ER and deubiquitinating it, enhancing IL-1β secretion and inflammatory responses.

This study identifies miR-466d-3p as a target of JEV NS3 that regulates IL-1β and viral replication through miRNA degradation.

The paper analyzes gene panel sequencing data from 829 Chinese high-risk breast cancer patients to identify pathogenic variants and variants of uncertain significance across 115 hereditary cancer susceptibility genes.

The paper models electron transfer in olfaction to explain odor recognition, showing emission spectra can distinguish similar odors and explain isotope effects.

The paper uses a transgenic mouse model to show RBC-derived extracellular vesicles target cardiomyocytes and microglia in ischemic heart failure, with targeted cells showing gene enrichment in proliferation and metabolism.

This paper introduces a microfluidic chip that improves single-cell encapsulation efficiency by fourfold, achieving a 3% co-capturing rate with low doublet rates in sequencing data.

The paper introduces a cell-centric metric to quantify viral invasion fitness, showing that strategies like lysogeny can outperform lytic strategies under certain conditions.

This paper introduces Tn5-FISH, a method to visualize chromatin interactions at sub-kilobase resolution and validate results from 3C-derivative methods.

This study uses oligotyping and genome-resolved metagenomics to identify distinct Candidatus Accumulibacter communities in different EBPR configurations, revealing new MAGs and clade-level diversity.

This study examines the energetics and stability of fish schooling using simulations, finding that energy expenditure and stability influence swimming patterns and synchronization.

SpitWorm, a robotic device, mimics insect herbivory by causing mechanical wounding and applying salivary components, inducing plant defense responses similar to real larvae feeding.

This study identifies molecular mechanisms of shade responses in maize by analyzing transcriptome changes and functionally testing a key transcription factor.

This study investigates how viral lysis products affect the transcriptome of Prochlorococcus, revealing changes in tRNA abundance, nitrogen metabolism, and photosynthetic efficiency.

The paper identifies and maps the stripe rust resistance gene YrTZ2 in wild emmer wheat and compares its genomic region with Aegilops tauschii.

The paper investigates SAM-SAM domain interactions in Eph receptors and identifies SAMD5 as a new binding partner, explaining disease-related mutations.

This study generates transgenic pigs expressing microbial enzymes to enhance feed digestion and reduce nutrient emissions, showing improved growth and lower environmental impact.

The paper sequenced 1,504 mutant lines in the rice variety Kitaake and established a database to enable rapid functional genomic studies.