H. Qiao

Time-lapse Image Super-resolution Neural Network with Reliable Confidence Quantification for Optical Microscopy

This paper introduces a time-lapse image super-resolution neural network with confidence quantification for optical microscopy, improving temporal consistency and reliability.

Cell-cycle and Age-Related Modulations in Mouse Chromosome Stiffness

This study measures chromosome stiffness in mouse oocytes across cell cycle stages and age, finding increased stiffness in metaphase I oocytes and age-related stiffness changes.

LHP1 and INO80 cooperate with ethylene signaling for warm ambient temperature response by activating specific bivalent genes

This study shows that LHP1 and INO80 work with ethylene signaling to activate specific bivalent genes in response to warm temperatures in Arabidopsis.

Histone acetyltransferase HAF2 associates with PDC to control H3K14ac and H3K23ac in ethylene response

This study identifies HAF2 as a histone acetyltransferase that interacts with EIN2-C and PDC to regulate H3K14ac and H3K23ac in response to ethylene.

Nuclear Pyruvate Dehydrogenase Complex Regulates Histone Acetylation and Transcriptional Regulation in the Ethylene Response

This study identifies the nuclear pyruvate dehydrogenase complex (PDC) as a key regulator of histone acetylation and transcription during ethylene response in plants.

Self-supervised denoising for structured illumination microscopy enables long-term super-resolution live-cell imaging

The paper introduces a self-supervised denoising method for structured illumination microscopy that enables high-quality super-resolution imaging with reduced fluorescence.

Zero-shot learning enables instant denoising and super-resolution in optical fluorescence microscopy

This paper introduces a zero-shot deep learning method for super-resolution microscopy that enhances resolution with less fluorescence and no training data.

Soft and stretchable organic bioelectronics for continuous intra-operative neurophysiological monitoring during microsurgery

This paper introduces a soft, stretchable organic bioelectronic system for continuous intra-operative neurophysiological monitoring during microsurgery, demonstrating improved signal quality and reduced post-operative complications in animal models.

Adverse PFAS effects on mouse oocyte in vitro maturation are associated with carbon-chain length and inclusion of a sulfonate group

This study shows that PFAS toxicity on mouse oocyte in vitro maturation depends on carbon-chain length and presence of sulfonate groups, with longer chains and sulfonates causing more severe reproductive toxicity.

Longitudinal white matter alterations in SIVmac239 infected rhesus monkeys with and without regular cART treatment

This study tracks white matter changes in SIV-infected rhesus monkeys with and without cART, finding early alterations at 4 weeks and varying cART effects over time.

Phosphorylation Status of B beta Subunit Acts as a Switch to Regulate the Function of Phosphatase PP2A in Ethylene-mediated Root Growth Inhibition

The paper shows that phosphorylation of Bβ subunit of PP2A acts as a switch to regulate PP2A activity, controlling EIR1 phosphorylation and auxin transport to modulate ethylene-mediated root growth inhibition.

Real-time denoising of fluorescence time-lapse imaging enables high-sensitivity observations of biological dynamics beyond the shot-noise limit

This paper introduces DeepCAD-RT, a real-time denoising method for fluorescence time-lapse imaging that improves signal-to-noise ratio with fewer photons, demonstrated across multiple organisms and biological processes.

Histone H3K4 methyltransferase DcATX1 promotes ethylene induced petal senescence in carnation

This study identifies DcATX1 as a histone methyltransferase that accelerates ethylene-induced petal senescence in carnation by regulating H3K4me3 levels and gene expression.

Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress

This study shows PFNA exposure impairs mouse oocyte maturation by causing spindle defects, mitochondrial dysfunction, oxidative stress, DNA damage, and apoptosis.

3D observation of large-scale subcellular dynamics in vivo at the millisecond scale

This paper introduces a method to observe 3D subcellular dynamics in vivo at high resolution and speed, demonstrating its application in various biological systems.

Accounting for dispersal improves the understanding of species abundance patterns

This study shows that species abundance patterns can vary depending on environmental suitability and dispersal ability, challenging the idea that abundance is always centered in space or niche.

Iodoacetic acid disrupts mouse oocyte maturation by inducing oxidative stress and spindle abnormalities

This study shows that iodoacetic acid (IAA) disrupts mouse oocyte maturation by inducing oxidative stress, spindle abnormalities, and DNA damage.

Micromanipulation of prophase I chromosomes from mouse spermatocytes reveals high stiffness and gel-like chromatin organization

The paper measures physical properties of mouse meiotic prophase I chromosomes, finding they are stiffer than mitotic chromosomes and have a gel-like chromatin organization.

Phenological matching drives wheat pest range shift under climate change

This study shows that climate change has caused a northward shift in the range of wheat pests, leading to increased crop damage despite pesticide use.

miR-425 suppresses EMT and inhibits the development of TNBC (triple-negative breast cancer) by targeting TGF-β 1/SMAD 3 signaling pathway

This study shows miR-425 suppresses EMT and TNBC development by targeting TGF-β1/SMAD3 signaling pathway through experiments in cell lines and xenograft models.

Investigation of novel functions of three genes in oriental river prawn, Macrobrachium nipponense: Molecular Cloning, Expression, and In situ Hybridization Analysis

This study investigates the functions of three genes in male sexual development and androgenic gland formation in M. nipponense using molecular cloning, expression analysis, and in situ hybridization.

YES1 amplification: a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics

This study identifies YES1 amplification as a novel mechanism of resistance to EGFR inhibitors in lung cancer using transposon mutagenesis and clinical genomic analysis.