J. Hu

This study uses CT scans to analyze the dental systems of three Jurassic ceratopsians, revealing tooth replacement patterns and dietary strategies that inform their evolution.

This study examines the bladder microbiome, metabolome, and cytokines in SLE patients, finding associations between microbial composition and disease-related metabolites and cytokines.

The paper evaluates competition between pathogens and probiotic cleaners on indoor surfaces, finding negligible impact on community composition but functional differences in gene expression.

This study assesses the infectivity and immune evasion of the Omicron SARS-CoV-2 variant using pseudotyped viruses and neutralizing assays against convalescent sera and vaccinated individuals.

This study identifies MDR1 as a mediator of resistance to PROTACs in cancer cells and shows that combining MDR1 inhibitors with PROTACs enhances drug efficacy.

The paper uses quantum mechanical modeling to predict and analyze binding strengths of SARS-CoV-2 spike variants to the human ACE2 receptor, validating predictions experimentally.

This study shows that glyphosate and its formulations Roundup Bioflow and RangerPro alter bacterial and fungal communities in rat caecum microbiomes, with formulations causing more pronounced changes than glyphosate alone.

This study shows that reducing dermal white adipose tissue (dWAT) worsens EGFR inhibitor-induced skin rash in mice, and activating PPARγ with rosiglitazone improves skin function without affecting antitumor effects.

The paper demonstrates predictable emergent diversity and dynamics in microbial ecosystems by showing transitions between distinct dynamical phases as species number or interaction strength increases.

This study shows HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition, with implications for neurodegenerative diseases like ALS.

This study compares proteomic profiles of vancomycin-intermediate resistant S. aureus strains to identify differentially expressed proteins associated with vancomycin resistance.

The paper evaluates the neutralization efficacy of inactivated and RBD-subunit vaccines against SARS-CoV-2 B.1.617 and B.1.1.7 variants using a pseudovirus-based assay.

This study shows that the hexapeptide WKYMVm promotes M2 macrophage polarization via the JAK1/STAT6 pathway, enhancing angiogenesis in bone repair.

This study shows Rac1-GTP peaks and nadirs regulate protrusion and retraction lifetimes in fibrosarcoma cells by controlling traction forces.

This study shows that introducing probiotic bacterial consortia to tomato plants enhances growth by increasing rhizosphere microbiome diversity and abundance of rare taxa, rather than directly adding beneficial traits.

This paper introduces SNU-seq, a method for single-nucleotide uracil mapping in DNA, validated on synthetic DNA and mammalian genomes, revealing uracil dynamics in treated cells and AID hotspots.

The paper identifies consistently expressed genes in pancreatic ductal adenocarcinoma (PDAC) to prioritize therapeutic targets and biomarkers.

This study identifies CycK:CDK13 as a kinase complex that phosphorylates SERINC5 at S360, enhancing Nef-mediated downregulation and counteracting its antiviral activity.

This study constructs high-resolution spatial transcriptomes of primary liver cancers to analyze spatial architecture and identify tumor microenvironment features.

This study investigates the preventive and therapeutic effects of R-salbutamol, S-salbutamol, and their racemic mixture in a mouse model of LPS-induced sepsis, finding R-salbutamol improves survival and lung function while S-salbutamol worsens outcomes.

This study identifies AGL16's role in regulating gene expression and flowering time in Arabidopsis, showing partial dependency on SOC1 and involvement in water loss and seed dormancy.

The paper identifies actin polymerization regulators that drive chiral actin swirling and left-right asymmetry in single cells and cell collectives.

This study identifies three ultrapotent SARS-CoV-2 neutralizing antibodies effective against B.1.351 variants, showing synergistic effects and protective efficacy in mice.

This study identifies renalase (RNLS) as a biomarker in pancreatic ductal adenocarcinoma (PDAC), showing elevated tissue and plasma levels correlate with worse tumor characteristics and reduced survival.

This study constructs two oncolytic adenoviruses carrying mK5 or MnSOD genes under survivin promoter control and shows their combined use significantly inhibits gastric cancer growth in vitro and in vivo.

This study uses CRISPR/Cas9 to induce homology-independent targeted integration in a rat hemophilia B model, achieving therapeutic correction with 3.66% knock-in efficiency and normalization of clotting time.

This study identifies AcMNPV orf13 as essential for efficient nuclear egress of nucleocapsids during virion budding but not for occlusion body formation.

This study develops a drug-resistant recombinant BCG vaccine that enhances second-line TB treatment efficacy in a murine model of drug-resistant tuberculosis.