J. Liu

This study identifies ESCRT-III homologs in magnetotactic bacteria, showing their role in membrane remodeling and multicellular morphogenesis through genomic and imaging analyses.

This study presents the first structure of a K+-independent M-PPase and shows asymmetric and time-dependent substrate binding, proposing a unified model for ion pumping and energy coupling in M-PPases.

The paper identifies RNA phase separation as a novel pathway for extracellular miRNA uptake and shows that these miRNAs are delivered to mitochondria via PNPT1.

The paper identifies a proliferative exhausted CD8+ T cell cluster in HPV-positive HNSCC that correlates with better patient survival and suggests potential therapeutic implications.

The paper shows that follicular regulatory T cells (Tfrs) suppress GC B cells acquiring nuclear proteins, indicating direct Tfr-GC B cell interactions regulate effector B cell responses.

This study identifies FlgV as a novel flagellar motor ring component in H. pylori that stabilizes interactions between MS and C rings and is essential for optimal motility.

This study compares neutralizing antibody titers after monovalent and bivalent mRNA boosters against SARS-CoV-2, finding comparable levels against BA.5.

This study introduces microsecond pulse electric field (sPEF) to enhance wound healing by promoting fibroblast migration and ECM alignment, validated in 2D and 3D models and a mouse wound healing assay.

This study develops an electromagnetic stretching device to apply controlled mechanical strain to endothelial cells, revealing strain-dependent cellular and nuclear orientation and the effects of overstretching on endothelial function.

This paper presents a coarse-grained model to predict 3D structures and stability of single- and double-stranded DNAs in ion solutions from their sequences, achieving accurate results for various DNA types and ion effects.

The paper identifies that only 2% of annotated miRNAs are likely to function as robust gene regulators based on their abundance, DROSHA dependence, and association with AGO proteins.

This study describes a new saurosphargid species from the Early Triassic of South China and presents a phylogenetic analysis clarifying the relationships of sauropterygians and their evolutionary history.

This paper introduces FD-DeepLoc, a deep learning method for high-throughput 3D super-resolution imaging over a large field of view using a sCMOS camera.

The paper presents a theoretical model predicting oscillations in cellular polarization during directional decision-making at junctions, validated experimentally in two cell types.

This study maps the dynamic trajectories of intracellular gene transfers in Poaceae using a novel tool, revealing lineage-specific patterns and functional roles of nuclear organelle genes.

This study identifies how avian-origin H3N2 influenza viruses adapt to dogs, acquiring traits that increase their potential to infect humans.

This study investigates the IFN{gamma}/chi-miR-3880/DDX58 axis in goat mammary gland lactation, showing its role in regulating proliferation, lipid formation, apoptosis, and involution through specific signaling pathways.

This study analyzes the genome and multi-omics data of a C4 plant to uncover evolutionary mechanisms behind C4 photosynthesis development.

This study evaluates the antiviral breadth of monoclonal and bispecific antibody cocktails against SARS-CoV-2 variants using a replication competent VSV-SARS-CoV-2 model, showing resistance to mutation in two cocktails.

The paper determines the structure of mycobacterial Complex I using cryoEM, revealing its composition and interactions with menaquinone and a unique lipid.

The paper identifies WSTF as a nuclear inhibitor of inflammation degraded by autophagy, showing its role in inflammation, cancer, and immune surveillance.

The paper identifies and characterizes unannotated proteins in green lineage species, finding many with novel structures and potential plastid functions.

The paper identifies and characterizes a novel hypovirus and its satellite-like dsRNA from Pestalotiopsis fici, showing it lacks a poly(A) tail and ORF, and negatively regulates the helper virus.

The paper shows that aging and cancer share an epigenetic replication signature linked to DNA methylation, which increases with age and correlates with cancer risk.

This study defines an interconverting ensemble of ePEC states using cryo-EM and biochemical analysis, showing that ePECs occupy pre- or half-translocated states without always swiveling.

This study identifies sialidases and fucosidases in Akkermansia muciniphila that degrade mucin glycans and enable nutrient sharing with gut bacteria.

This paper improves CRISPR-Cas12a genome editing by combining rational engineering and directed evolution to enhance homology-directed repair efficiency.

This study shows that synthetic sensor NLR receptors require multiple interfaces within and outside their integrated domain to recognize noncorresponding effectors and activate resistance.

This study identifies ZmGL8 as a key gene regulating the balance between cuticular wax production and jasmonic acid-mediated defenses in maize, showing its role in modulating plant defense responses.

This study analyzes blood microbiome data from 9,770 healthy humans and finds no evidence of a common or consistent blood microbiome.