J. Xu

This paper designs and tests SARS-BLOCK peptides as antidotes to SARS-CoV-2 by inhibiting spike protein-ACE2 binding and enhancing neutralizing antibody responses.

This study examines how wildfire and its legacy through charcoals affect soil microbial communities in boreal forests over a 29-year chronosequence.

The paper sequenced genomes of Pneumocystis species from different mammals to study host specificity and evolutionary adaptations, revealing insights into the emergence of the human pathogen P. jirovecii.

The paper develops an electrodialysis/phase separation cell to directly extract medium-chain carboxylic acid oil from bioreactor broth, achieving higher efficiency than membrane electrolysis with pertraction.

This study develops a virus-free live-cell visualization system for SARS-CoV-2 entry using a fluorescent spike trimer probe, enabling analysis of neutralizing antibodies and inhibitors.

This study shows that SETD2 deficiency disrupts the β-catenin destruction complex, promoting ccRCC formation, and links SETD2-mediated H3K36me3 to Wnt/β-catenin signaling in renal cancer.

This study identifies potent human neutralizing antibodies against SARS-CoV-2 from convalescent patients, with some showing high efficacy in blocking viral entry.

This study reveals that Smoothened (SMO) activates GLI transcription factors by sequestering PKA catalytic subunits at the membrane, bypassing traditional GPCR signaling mechanisms.

This paper develops a nanoparticle platform for BBB-independent siRNA delivery in TBI, achieving higher brain accumulation and gene silencing through surface chemistry and coating density modulation.

This study investigates the biodegradation of polyester polyurethane by Aspergillus flavus G10 using multiple analytical techniques and identifies conditions that enhance degradation.

The paper tests the Red Queen hypothesis by analyzing two Drosophila de novo miRNAs, finding their fitness contributions vary between species, supporting their different evolutionary fates.

This paper develops a rapid, low-cost method to detect and quantify SARS-CoV-2 virus particles using nanoplasmonic sensors in microplate readers and smartphone devices.

This study identifies amlodipine as a drug that reduces PD-L1 expression and enhances antitumor immunity by blocking calcium flux and autophagic degradation of PD-L1.

This study develops a SARS-CoV-2 vaccine candidate using virus simulating particles that induces strong neutralizing immune responses with a single dose.

This study evaluates a long-acting tenofovir alafenamide nanofluidic implant in nonhuman primates, showing partial protection against SHIV infection.

This paper identifies a potent neutralizing antibody targeting the N-terminal domain of SARS-CoV-2 Spike protein, revealing it as a new therapeutic target.

The paper uses scRNA-Seq and scATAC-Seq to analyze human blood cells, identifying proliferative progenitors and epigenetic priming in haematopoiesis.

This study investigates tree shrew susceptibility to SARS-CoV-2 infection and finds that they show mild symptoms and low viral replication, suggesting limited susceptibility.

The paper shows that lateral mechanical impedance, not frontal, promotes cortical expansion and radial growth in maize roots.

The paper withdraws its manuscript due to the need for further experiments to validate conclusions.

This study creates a single-cell transcriptome atlas of a non-human primate to explore SARS-CoV-2 targets and immune responses, identifying potential therapeutic targets and mechanisms linking IL6 to viral entry.

The paper identifies antimalarial siderophores from mosquito microbiomes that reduce mosquito reproduction and inhibit Plasmodium parasites.

This study compares SARS-CoV-2 infection outcomes in three non-human primate species, finding that M. mulatta is most susceptible, followed by M. fascicularis and C. jacchus.

This paper develops freeze-dried PCR mixes for SARS-CoV-2 detection that can be stored at room temperature, maintaining sensitivity and specificity for up to 28 days.

This study reports cryo-EM structures of a P4-ATPase lipid flippase in lipid bilayers, revealing mechanisms of lipid transport and ATP coupling.

This study analyzes SARS-CoV-2 genome data to infer its evolution and population demography using phylogenetic and population genetics methods.

The paper uses a within-host viral dynamic model to estimate the basic reproductive numbers of SARS-CoV-2 and MERS-CoV using chest radiograph data.

The paper identifies a germline non-coding GATA3 variant that alters chromatin topology and contributes to Ph-like ALL by activating an enhancer and reshaping 3D genome organization.

The paper investigates how motility and adhesivity of Leptospira spp. relate to their pathogenicity by analyzing their movement on host tissues.

This study uses ultra-deep sequencing to analyze clonal mutations in sun-exposed and non-sun-exposed skin, finding higher UV-signature mutations and mutation burden in sun-exposed samples.