L. Ma

This study shows GT0918 reduces cytokine release and inflammation in COVID-19 by inhibiting NF-κB and activating NRF2, suggesting its potential for treating both mild and severe cases.

The paper identifies a P4-ATPase gene in a fungus that mediates detoxification of immunosuppressants via vesicle transport, with cross-species resistance applications in plants and human health.

This study characterizes Gp105, a lysozyme murein hydrolase from Enterobacter phage myPSH1140, showing broad-spectrum antibacterial activity against Gram-negative pathogens.

The paper shows that controlling for both DNA and taxa abundances improves differential analysis in metatranscriptomics data.

This paper develops a Cas9-RNAi RNP tool that combines RNAi and CRISPR for simultaneous gene knock out and knock down, and enhances homology-directed repair.

The paper investigates how alternative 3' UTRs regulate gene expression in response to high salt stress in Spartina alterniflora, showing that 3' UTR lengthening enhances RNA stability and protein synthesis of stress-related genes.

This study shows that boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibodies and protection against B.1.1.529 in mice, with the Omicron-matched booster showing slightly better outcomes.

The paper shows lung-derived C3 reduces pneumonia-induced lung injury through the Factor B pathway, independent of circulating C3 levels.

This study shows that knocking out OsSWEET15 in rice reduces fertility by impairing embryo formation and seed-setting, with similar effects observed in OsSWEET11 mutants.

This paper introduces SpRYgests, a CRISPR-based DNA cloning method that enables precise cleavage at any sequence, improving cloning workflows and reducing costs compared to restriction enzymes.

The paper develops a hybrid MELD-NMR approach to determine structures of flexible protein-polypeptide complexes using only NMR chemical shift data, achieving accurate results for ET domain-BET protein interactions.

This study identifies a new structural class of fungal effectors in Fusarium oxysporum f. sp. lycopersici using experimental and computational methods, revealing structural relationships and immune recognition mechanisms.

The paper identifies GbNGT1, an N-glucosyltransferase that catalyzes IAA and IAA-amino acid glucosylation, completing the auxin metabolic pathway.

The paper compares DNA and RNA microbial communities in Miscanthus x giganteus soil under different nitrogen fertilization rates, finding RNA-based communities better reflect nitrogen-cycling taxa.

The paper introduces Yn situ, a single RNA molecule in situ detection method, showing it is sensitive and quantitative for gene expression in mouse olfactory epithelia.

The paper shows that kidney injury affects cell clustering in scRNA-Seq by reducing specific cell groups and markers, emphasizing the need for histology screening before analysis.

This paper improves the production of disulfide-bonded fungal effectors in E. coli using CyDisCo and FunCyDisCo co-expression systems, enabling functional studies and crystallisation.

The paper introduces a universal microfluidic method for studying bacterial biofilms, demonstrating insights into H2O2 resistance and resource retention mechanisms in E. coli and P. aeruginosa biofilms.

This study shows that the intracellular glycosyl hydrolase PslG affects signaling, ePsl structure, cyclic-di-GMP levels, and biofilm formation in Pseudomonas aeruginosa.

This study shows that maternal exposure to dibutyl phthalate during pregnancy and lactation leads to increased visceral obesity in adult female offspring without affecting serum glucolipid levels or the PI3K/AKT pathway in muscle.

This paper introduces a CRISPR-nCas3 system for efficient genome editing in bacteria, enabling high-efficiency deletion of large genomic regions.

The paper shows YBX1 phase separation enables selective sorting of miR-223 into exosomes by recruiting it into condensates that facilitate RNA packaging.

OsciDrop generates size-tunable, monodisperse droplets on demand without microfabrication, enabling chip-free droplet assays for applications like virus quantification.

The paper identifies enhancer heterogeneity in gastric cancer by integrating epigenomic data and functional assays, linking it to genetic and regulatory factors.

The paper investigates how complexin-1 regulates the assembly of SNARE complexes by stabilizing partially folded states and interacting with specific regions of SNARE proteins.

This study evaluates updated SARS-CoV-2 mRNA vaccines in mice, showing that mRNA-1273.351 boosts neutralization against B.1.351 and mRNA-1273.211 provides broad cross-variant protection.

This study shows sustained oxygenation improves diabetic wound healing by enhancing epithelialization, angiogenesis, and reducing inflammation without drugs.

This study identifies BIRG1 as a chloride efflux transporter in rice that regulates grain size and salt tolerance by controlling chloride homeostasis.

This study shows that apoptotic extracellular vesicles (apoEVs) protect liver homeostasis and regeneration by forming a chimeric organelle with the Golgi apparatus and restoring hepatic ploidy.

The paper shows that complement activation is higher in severe SARS-CoV-2 infection compared to influenza and non-COVID respiratory failure, with the alternative pathway linked to worse outcomes.