S. Liu

This study shows PRV infection increases oxidative stress and apoptosis in mouse spleen, with elevated ROS and MDA levels and reduced antioxidant enzymes.

The paper examines DNA sequence variation in rice blast fungi, finding that heterochromatin-associated histone marks correlate with SNP and INDEL frequency, even after accounting for selection.

This study shows that Urolithin A improves mitochondrial function and cardiac health in aging and heart failure models.

The paper identifies AP2A1 upregulation in senescent human fibroblasts, which strengthens focal adhesions via integrin β1 translocation along stress fibers, maintaining large cell size.

The paper constructs a super-pangenome of 19 Populus species to explore genomic factors driving adaptation and diversification in forest trees.

This study shows that combining proguanil and chlorhexidine with clarithromycin or rifampicin enhances antibacterial activity against Acinetobacter baumannii in vitro and improves treatment outcomes in mice.

This study examines how diabetes and hypertension affect vasomotion spectral characteristics at specific acupoints using Laser Doppler Flowmetry and signal analysis techniques.

This study investigates how chronic pain affects oxycodone seeking behavior and neuronal activity in the dorsomedial prefrontal cortex, finding sex-specific differences in these effects.

This study investigates the molecular dynamics of persister formation in Staphylococcus aureus under vancomycin and enrofloxacin exposure, revealing stress-specific molecular profiles and the potential of combined therapies.

This study identifies cadheropodia, Rac1-dependent actin structures in ground-state mESCs, which may serve as markers for pluripotency.

This study investigates how MeCP2 interacts with methylated DNA and nucleosomes, revealing distinct dynamics that influence its function in gene repression and Rett syndrome.

This study shows that low-level vinyl chloride exposure combined with a Western diet increases liver cancer risk in mice through metabolic and epitranscriptomic changes.

The paper introduces an improved light-sheet microscope that increases imaging speed and signal strength for large tissue samples.

AutoUnmix is a deep learning-based spectral unmixing method for multi-color fluorescence microscopy that outperforms existing methods in speed and accuracy.

This study identifies neo-functionalization and co-option of Pif genes in oysters that contribute to the evolution of a novel shell microstructure called chalky calcite.

The paper introduces a binding-based screen to identify cooperative small-molecule inducers of protein-protein interactions, identifying a compound with high cooperativity comparable to classical molecular glues.

The paper investigates 12-hour ultradian rhythms in gene expression and metabolism in animals lacking a circadian clock, finding evidence for a cell-autonomous 12-hour oscillator.

This study uses phylogenomic data to show widespread gene flow and reticulation during the early radiation of oaks and related genera.

The paper reports cryo-EM structures of the Schizosaccharomyces pombe Clr6S complex, revealing its active site and interactions with a nucleosome.

OpenABC simplifies GPU-accelerated simulations of biomolecular condensates using Python, offering performance comparable to hundreds of CPUs and tools for converting to all-atom structures.

The paper introduces a method to label and profile cell-cell interactions with high sensitivity and spatial-temporal resolution using a bioorthogonal photocatalytic quinone methide decaging strategy.

This study introduces opto-lipidomics, a technique that uses vibrational Raman spectroscopy combined with mass spectrometry to visualize and identify lipids in tissues with high molecular specificity.

This study shows asparagine starvation reduces histone demethylation by depleting labile iron, which is essential for JHDMs function, and this effect is mediated through IREB2 and TFRC regulation.

This study presents haplotype-resolved genomes of triploid bananas, revealing subgenome asymmetric evolution and resistance mechanisms against banana wilt.

This study uses single-cell transcriptomics in Drosophila to show glial cells integrate circadian and homeostatic processes to regulate sleep-wake cycles.

This study shows K8.1 is critical for KSHV infection in epithelial cells but not in B cells, functioning at the attachment step.

This study characterizes the catalytic and non-catalytic mechanisms of SUV420H1 by determining cryo-EM structures and showing its role in DNA accessibility and chromatin condensation.

This study shows that IgA BCR signaling enhances B cell fitness and promotes diverse IgA responses to gut commensals by rescuing low-affinity B cells and redirecting plasma cell homing.

This study shows DHA inhibits glioma migration and invasion by upregulating ecDNA-BASP1, which suppresses EMT.