Y. Wang

This study identifies Avr1d as a Phytophthora sojae effector that inhibits GmPUB13 E3 ligase activity by competing with E2 ubiquitin conjugating enzymes, stabilizing the susceptibility factor and facilitating infection.

This study assesses the reporting quality of trend analyses in leading medicine and oncology journals from 2008-2018, finding moderate quality with room for improvement.

This study evaluates phage-based FMDV vaccines through meta-analysis and experiment, showing protective effects and immune responses in mice.

A potent neutralizing antibody protected against SARS-CoV-2 in an hACE2 mouse model by blocking viral receptor interaction.

The paper uses intravital imaging to show macrophage-induced cancer stem cells (CSCs) are enriched at TMEM doorways during metastasis, with CSCs comprising >60% of circulating tumor cells.

The paper presents a phylogenomic method to assess hybridization and introgression's role in trait evolution, showing gene flow can lead to misleading trait evolution hypotheses.

This paper uses molecular dynamics simulations to study ACE2 flexibility in SARS-CoV-2 infection, finding structural dynamics that may aid viral entry and therapeutic design.

The paper uses genome and transcriptome data from Olpidium to analyze its phylogenetic position relative to non-flagellated terrestrial fungi, finding it as the closest zoosporic relative.

This study exposes C. elegans strains to E-liquids and finds reduced lifespan, movement, and mitochondrial organisation in a pink1 mutant strain, even with nicotine-free flavours.

The paper develops SARS-CoV-2 vaccine candidates by displaying the receptor-binding domain and a stabilized spike on self-assembling protein nanoparticles, showing enhanced neutralizing antibody and T-cell responses.

This study shows that RANKL from bone marrow adipocytes regulates trabecular osteoclast formation and bone loss in mice, with implications for therapeutic targeting of bone marrow adiposity.

This study identifies a linear epitope on SARS-CoV-2 S-RBD recognized by a potent neutralizing antibody and shows its potential for vaccine design.

The paper identifies lineage-specific human placental enhancers associated with endogenous retroviruses, revealing their role in placental evolution.

This study characterizes the disordered C-terminal tail of ErbB2 at atomic resolution, revealing structural features that suggest functional roles in auto-regulation and protein interactions.

The paper analyzes viral diversity in deep sea cold seep sediments, finding high endemism and links to microbial hosts and biogeochemical cycling.

The paper assesses the impact of different land-use scenarios on ecosystem services in Nanjing from 2000 to 2015, showing varying effects on carbon storage, habitat quality, and water yield.

This study investigates the degradation pathway of a disease-linked ASPA variant, finding it is degraded via the proteasome and dependent on Hsp70 and Hsp110.

This study identifies TaGS1.1 as critical for nitrogen assimilation and spike development in wheat by analyzing CRISPR-edited mutants and their growth responses under varying nitrogen conditions.

This paper develops an intestine-on-chip model to study SARS-CoV-2 infection, showing intestinal damage and immune response similar to human infection.

The paper shows that naive T cells exhibit transcriptional heterogeneity influenced by cytokines like IL-4, leading to hysteresis in immune responses.

This paper presents a method for site-specific covalent labeling of large RNAs using expanded genetic alphabet transcription and gold nanoparticles, validated by X-ray scattering interferometry.

This paper develops a deep learning system for gastric cancer detection using histopathological images, achieving high sensitivity and robust performance across different scanners.

This study shows that the S1/S2 boundary of the SARS-CoV-2 spike protein affects cell entry and transmission by altering the pathway used for viral entry.

This paper identifies a novel allele of the chromogen gene C from wild rice that regulates anthocyanin biosynthesis differently in indica and japonica subspecies.

This study shows that mechanical deformation of fibrin induces structural changes that affect its biochemistry and platelet interactions, revealing a mechano-chemical feedback loop.

The paper constructs a genome-scale fungal phylogeny using 1,644 species and multiple data matrices, finding robust relationships and identifying taxonomic discrepancies.

This paper introduces a rapid screening system to identify potent neutralizing antibodies against SARS-CoV-2 and demonstrates its effectiveness in discovering high-potency antibodies.

This study develops a cell-based chimeric vaccine against SARS-CoV-2 that induces strong T cell immunity and neutralizing antibodies without toxicity.

This study identifies loss-of-function mutations in efflux pumps as a mechanism for increased antibiotic susceptibility in Neisseria gonorrhoeae cervical isolates.