D. Liu

This study examines the environmental impact of administrative division adjustments on Chaohu Lake using a quasi-natural experiment and synthetic control method, finding mixed effects on water quality indicators.

This paper introduces a method to improve cryo-EM analysis of RNA structures by engineering kissing-loop sequences for homomeric assembly, achieving high-resolution reconstructions of RNA molecules.

This study shows Brsk2 amplifies parasympathetic signals to promote type 2 diabetes by enhancing β-cell insulin secretion in obese mice and associates human BRSK2 variants with metabolic disorders.

This study demonstrates that S309-CAR-NK cells effectively target and kill SARS-CoV-2-infected cells, including the D614G mutant, outperforming CR3022-CAR-NK cells in vitro.

This study identifies new CCHFV strains in Inner Mongolia, China, showing genetic similarities to strains from Xinjiang and South Africa, suggesting long-term prevalence in the region.

This study shows that Tmem138 is essential for rhodopsin transport across the photoreceptor connecting cilium and outer segment biogenesis, with its absence causing photoreceptor degeneration.

This study shows that SPOP mutations in prostate cancer alter the chromatin landscape and AR-driven transcription, making tumors more responsive to AR-targeted therapies.

This study identifies 12 serum metabolites associated with esophageal squamous cell carcinoma and highlights pipecolic acid as a predictive biomarker for tumorigenesis.

This paper introduces a synthetic platform using coiled-coil peptides to dynamically display cell adhesive signals and studies how temporal ligand exposure affects cell spreading and integrin dynamics.

The paper introduces a rapid antimicrobial efficacy profiling method using clinical urine specimens, achieving 100% agreement with conventional AST methods for specific antibiotics.

This study shows that mice lacking PDE9 are resistant to obesity and have increased energy expenditure on a high-fat diet, with improved glucose handling and reduced hepatic steatosis.

The paper identifies MIK2 as a plant receptor that recognizes conserved peptide motifs from phytocytokines and microbial proteins, triggering immune responses through a signaling relay.

This study identifies rosmarinic acid as a potent inhibitor of amylin aggregation and shows its efficacy in reducing amyloid deposits and mitigating diabetic pathology in HIP rats.

This study finds a significant association between Kaposi's Sarcoma Herpesvirus (KSHV) infection and osteosarcoma in the Xinjiang Uyghur population, identifying KSHV as a potential risk factor and a newly identified viral-associated cancer.

The paper develops a method to trace the geographic origin of quarantine insects using their gut microbiota, finding that microbiota diversity and composition correlate with geographic and environmental factors.

This study identifies immune markers, including HLA-DR and CTLA-4 expression on CD4 T cells, that predict HBsAg loss in chronic hepatitis B patients.

This study compares gene expression in oil pathways between yellow and purple nutsedge to identify factors contributing to high oil accumulation in yellow nutsedge tubers.

This study identifies structural variants in Brassica oleracea genomes that contribute to morphological divergence between cauliflower and cabbage.

This study uses TRACE-seq to analyze single throat swabs, integrating SARS-CoV-2 genome, microbiome, antibiotic resistance, and host response data.

This paper introduces MOAlmanac, a clinical interpretation algorithm that integrates genomic and transcriptional data to improve precision cancer treatment decisions by considering second-order molecular features.

The paper investigates fungal and yeast communities in spontaneous wine fermentations, finding geographic differentiation and S. cerevisiae's role in shaping wine aroma profiles.

This study identifies the ERK2-p53 complex as a therapeutic target in KRAS-mutant stomach/colorectal cancers, showing that disrupting it with MEK1/2 and ERK2 inhibitors induces apoptosis.

This paper develops CR3022-CAR-NK cells to target SARS-CoV-2, showing they can bind viral proteins and kill infected cells in vitro.

This study shows PKD1 phosphorylates CBX8, disrupting PRC1 complex binding and promoting cell senescence by derepressing p16.

The paper analyzes SARS-CoV-2 genome sequences to study mutation patterns and evolutionary dynamics, identifying mutations that may enhance viral fitness and provide insights for vaccine development.

This study characterizes the subcellular localization of SARS-CoV-2 proteins using expression in human cells and immunofluorescent assays, revealing their association with various organelles.

The paper identifies new integrin antibodies that inhibit fibrosis progression in lung injury models and show superior in vitro activity in fibroblasts.

The paper predicts the binding ability between SARS-CoV-2 spike protein and human ACE2, revealing adaptive mutations that enhance transmissibility in humans.