H. Zhang

This study shows GCN5 acetylates YY1, reducing its DNA binding and increasing dystrophin expression, which maintains muscle integrity in mice.

This study sequenced and compared the genomes of two Sphingomonadaceae strains, revealing shared lutein synthesis genes and unique genes for hepatotoxin degradation in Sphingopyxis USTB-05.

This paper shows that lipoylated H-protein can catalyze glycine cleavage and synthesis reactions in vitro without the other GCS proteins.

This paper develops a method to create 3D vascularized tissues using bioprinting and surgical anastomosis, showing improved viability and functionality in liver-like constructs.

This study shows that small spherical AuNPs can deliver siRNA efficiently to plant leaves without entering cells, challenging the need for nanoparticle internalization in RNA delivery.

This paper develops a method using gold nanoclusters to deliver siRNA into plant cells, achieving efficient gene knockdown with minimal toxicity.

This study examines factors driving radiating diversification in Saussurea using Miocene to present data, finding increased diversification rates linked to climate fluctuations and adaptive traits.

This study evaluates glycoproteomics software performance using human serum datasets, identifies high-performance strategies, and provides recommendations for improved analysis.

This study examines how Brucella outer membrane proteins and mutants affect dendritic cell maturation and antigen presentation in mice, revealing their roles in immune evasion and pathogenesis.

This study compares the metabolic profiles of sweet potato leaves grown in soil versus hydroponic systems to identify metabolites associated with taste quality differences.

The paper develops fluorescent probes to visualize SARM1 activation and identifies a nisoldipine derivative as a SARM1 inhibitor that protects axons from degeneration.

The paper shows that complement activation is higher in severe SARS-CoV-2 infection compared to influenza and non-COVID respiratory failure, with the alternative pathway linked to worse outcomes.

This study transfers functional mitochondria into aged CD4+ T cells, improving their metabolism, reducing oxidative stress, and enhancing immune function against infections.

This study compares the effects of drought and warming on two pasture species, finding drought has a stronger negative impact on biomass, morphology, and nutritional quality than warming.

This paper introduces a deep learning method to improve light-field microscopy, enabling high-speed, artifact-free volumetric imaging of biological processes.

Eliglustat inhibits autophagy in osteoclasts, reducing MM bone disease and suggesting its use as a treatment for bone loss disorders.

This study uses evolutionary models of HCV subtypes 1a and 1b to explain differences in disease outcomes, finding that subtype 1b has lower fitness constraints leading to higher chronicity.

This study shows that 20-HETE enhances pericyte contractility and cerebral blood flow autoregulation in rats by modulating vascular smooth muscle cell function.

This paper develops a chip-based system combining microfluidics and light-field microscopy with deep learning to high-speed 4D image and analyze moving C. elegans.

The paper uses molecular dynamics simulations to study Piezo1 channel opening and identifies a multi-fenestrated ion permeation pathway.

The paper investigates the proteomic composition of the pathogen-host interface in cholera using a rabbit model and identifies SP-D as a novel intestinal defense factor.

This study evaluates SARS-CoV-2 entry mediated by ACE2 from 11 species, finding that pangolin and some mammals allow entry, while others do not, suggesting complex cross-species transmission potential.

This paper designs a biomimetic aramid nanofiber nanocomposite insulation material for implantable bioelectronics using graph theory analysis to mimic cartilage structure, showing improved adhesion and biocompatibility compared to Parylene C.

This study shows that HIV-1 signal peptide diversity affects Env glycosylation and antibody recognition of V1V2 epitopes.

This study examines the effects of drought and warming on pasture productivity in a field experiment, finding significant yield reductions and highlighting the negative impacts of climate extremes on forage availability.

Microbe-seq enables strain-resolved genome reconstruction from complex microbial communities, revealing intra-phylum horizontal gene transfer and bacteriophage-bacterial associations in the human gut.

This study examines how varying calcium concentrations affect the growth and encystment of Scrippsiella trochoidea, finding increased cell density and cyst formation at lower calcium levels, with reductions at higher concentrations.

The paper investigates the colonization history of the rosy apple aphid across Europe, North America, and North Africa using genetic and microbiota data, finding weak genetic differentiation and limited role of secondary endosymbionts in its spread.

A Fc-modified human antibody prevents SARS-CoV-2 viral infection via nasal administration.