J. Liu

This study identifies 12 serum metabolites associated with esophageal squamous cell carcinoma and highlights pipecolic acid as a predictive biomarker for tumorigenesis.

The study compares antibody responses in asymptomatic and symptomatic SARS-CoV-2感染者, finding that symptomatic individuals maintain higher and longer-lasting IgG and neutralizing capacities.

This study shows septin filaments are isodesmic polymers, and regulatory proteins modulate their biophysical properties to form different structures in yeast.

This study shows that EGCG from green tea inhibits SARS-CoV-2 and its variants by blocking spike protein binding to ACE2 receptors.

This study compares biomechanical parameters of weightlifting overhead pressing derivatives and jump squat to assess their effectiveness in improving vertical jump performance.

This study uses Raman spectroscopy and DFT calculations to distinguish three optical isomers of all-trans astaxanthin based on differences in Raman band intensities.

This study identifies and characterizes two CoAT enzymes from bacteria, showing CPB6-CoAT can catalyze both butyrate and caproate synthesis, while BEY8-CoAT only catalyzes butyrate synthesis.

This study identifies SSR1 as a chaperone-like protein that enhances HSCA2-ISU1 interaction in the mitochondrial iron-sulfur cluster biosynthesis pathway, essential for plant mitochondrial function.

This study identifies recurrent chromosome fusions and gene losses in parrots, revealing the role of transposable elements and genetic drift in neo-sex chromosome evolution.

The paper shows the N501Y spike mutation in SARS-CoV-2 enhances viral transmission in hamsters and human airway cells by increasing receptor binding affinity.

This paper presents a hardware-software solution for co-registering photoacoustic tomography and MRI images in vivo, demonstrating hybrid-contrast imaging of tumor microenvironments.

This study develops a drug-resistant recombinant BCG vaccine that enhances second-line TB treatment efficacy in a murine model of drug-resistant tuberculosis.

A natural allele of rice UMP1 promotes resistance to multiple pathogens by boosting H2O2 accumulation.

The fungal pathogen Ustilaginoidea virens disarms chitin-triggered immunity in rice flower via a secreted chitinase, revealing a mechanism of disease susceptibility.

The paper shows desmosomes have a stable core and a dynamic plakophilin module, with Pkp2a remaining mobile during desmosome maturation and down-regulation.

This study shows SGK1 promotes glucose metabolism and cell survival in ECM-detached cells by enhancing glucose uptake and PPP flux for ATP production.

This study identifies BPLF1 as a regulator of TOP2 activity during EBV replication by modulating ubiquitination, SUMOylation, and DNA-damage response.

This study shows that Withaferin A promotes white adipose browning and prevents obesity by activating the Prdm16-FATP1 pathway via the sympathetic nervous system.

This paper identifies SAM competitive inhibitors of SARS-CoV-2 nsp14 methyltransferase and characterizes their mechanism, guiding the development of selective bi-substrate inhibitors.

This study shows that TGF-β signaling suppresses TCA cycle enzyme expression in renal cancer, leading to reduced mitochondrial metabolism and tumor growth.

This study investigates how the loss of staging habitats affects migration strategies and population dynamics in migratory birds through phenotypic plasticity.

This study uses AIE dots for non-invasive NIR-IIb fluorescence hysterography to visualize uterine structures and function in mice without impairing reproductive capacity.

This study shows archaeal extracellular vesicles, produced via ESCRT machinery, transfer DNA and support nutrient cycling in extreme environments.

This study identifies SPX1 and SPX3 as regulators of phosphate homeostasis, mycorrhizal colonization, and arbuscule degradation in Medicago truncatula.

This study shows R13, a TrkB agonist, improves mitochondrial function and reduces AD-related pathology in 5xFAD mice by enhancing biogenesis and metabolism.

The paper shows that mDia1-mediated actin polymerization at focal adhesions reduces tension on stress fibers, preventing mechanical damage and enabling repair.

This study shows maternal obesity differentially programs gene expression in adipose tissues of male and female offspring, contributing to sex-dependent metabolic complications.

This study identifies TiAP1 from Thinopyrum intermedium as a resistance gene against Blumeria graminis f. sp. tritici, showing it interacts with BgtCDA1 and enhances wheat resistance through immune activation.

This study shows that sublingual immunotherapy with recombinant dog allergens reduces airway hyperresponsiveness and type 2 inflammation in a mouse model of dog allergy.