L. Zhang

The paper shows that targeting cystine import induces ferroptosis in pancreatic tumors, leading to tumor regression and improved survival in a mouse model.

This study identifies genetic features of recurrent pancreatic cancer through sequencing and finds that treatment-induced genetic changes and potential second primary tumors influence recurrence.

This study shows HIV-1 Vpr suppresses IRF7 and IFN-I expression in pDCs by degrading TET2, thereby enhancing HIV-1 replication.

This study identifies cell cycle-dependent phosphorylation and dephosphorylation of metabolic enzymes in budding yeast, revealing mechanisms linking the cell cycle to metabolic regulation.

This study identifies lncRNA AVAN as a positive regulator of antiviral innate immunity by interacting with TRIM25 and enhancing FOXO3a transcription.

The study investigates the impact of Bt-506 corn leaf litter on Collembola and decomposition rates, finding no significant effect of Bt protein but differences due to litter composition.

The paper withdraws a preprint due to errors corrected in a published version, and advises against citing the preprint.

This study develops WGA-pHRho, a fluorescent pH sensor to visualize proton fluxes on the extracellular surface of cells, showing correlation between pH changes and proton channel activity.

This study shows CpG-ODN 2007 reduces mortality and toxicity in zebrafish infected with Vibrio vulnificus and modulates immune gene expression.

This paper identifies a jasmonic acid regulatory module controlling spikelet fertility in sorghum, showing that mutations in MSD1 and MSD2 increase grain number per panicle.

This study compares the shapes and sizes of prostate lesions in dogs treated with laser, radiofrequency, and microwave ablation, finding significant differences in lesion morphology and volume.

This paper investigates the hydrodynamics of flying fish taxiing on water surfaces before take-off, finding that taxiing requires significantly less power than swimming and allows for higher speeds.

The paper develops an MS-based proteogenomic approach to identify non-canonical HLA peptides in tumors, finding hundreds of shared and tumor-specific peptides, including an immunogenic one from ABCB5.

This study shows that Cas9 uses biased one-dimensional diffusion along dsDNA to efficiently locate its target, with diffusion length quantified at 27 bp.

This study shows TRIM21 and PHLDA3 regulate cross-talk between PI3K/AKT signaling and PPP metabolism, with implications for cancer therapy.

This study shows that CHL1 overexpression reverses chemoresistance to cisplatin and paclitaxel in lung cancer by inhibiting the Akt pathway.

This study compares in vitro and in vivo drug responses to Artesunate in HepG2 cells, finding discrepancies in efficacy and biomarker expression.

This study investigates the metabolic role of ANGPTL8 in mice, showing improved glucose tolerance and reduced triglycerides, with insulin and glucose having distinct regulatory effects in liver and adipose tissue.

This study determines the cryo-EM structure of RyR1 and uses simulations to analyze cation hydration and conduction mechanisms in the receptor.

This study identifies GT198 mutations in stromal cells as a common cause of prostate and bladder cancers and suggests GT198 as a therapeutic target.

This study shows that IFITMs inhibit trophoblast cell fusion and enhance antiviral resistance in BeWo cells.

This study finds that withdrawing prophylactic antimicrobials from pigs does not change the resistome, suggesting fitness costs of antimicrobial resistance may be overestimated.

This study demonstrates that engineered cyanobacteria can produce hyaluronic acid from CO2 and sunlight, achieving high yields through genetic modifications.

The paper predicts and validates common neoantigens in colorectal cancer that are both presented and immunogenic, identifying potential universal targets for immunotherapy.

This paper optimizes violacein extraction and culture conditions in Yarrowia lipolytica to improve yield and purity, establishing a scalable production platform.

The paper shows monoclonal antibodies against Candida albicans Hyr1 protect against Gram-negative bacterial infections.

The paper uses natural sequence variation in the FRI locus of Arabidopsis thaliana to identify two amino acid changes in the central domain that disrupt protein function.

The paper compares TCR convergence detected by two sequencing platforms in cancer patients and finds Illumina-based sequencing shows higher convergence, which can be used to predict treatment response.