X. Lin

The paper analyzes divorce rates in birds using phylogenetic methods and finds male promiscuity and migration distance correlate with higher divorce rates.

This study identifies and characterizes the N-terminal domain of the Atlantic sea lamprey corticoid receptor, showing its critical role in steroid-mediated transcriptional activation and promoter-specific regulation.

The paper identifies a self-renewing muscle satellite cell state using single-cell chromatin accessibility profiling and shows TGFBR3 as a marker for these cells.

This study shows ovarian cancer cells inhibit pancreatic cancer growth in vitro and in vivo, with enhanced effects from elephant TP53 gene expression, suggesting a novel non-immunotherapy approach for pancreatic cancer treatment.

This study uses a near atomistic model to show that chromatin fibers break into clutches and trimers/tetramers under tension, supporting a hypothesis of in vivo chromatin configurations as folding intermediates.

The paper develops a mass-flow immigration model to quantify influent microorganism immigration efficiency and their contribution to organic substrate consumption in activated sludge.

This study identifies the RAM signaling pathway's role in CO2 and thermotolerance in Cryptococcus neoformans and discovers novel regulators of virulence.

The paper identifies novel resistance genes in Solanum americanum against Phytophthora infestans by analyzing genome variation and effector recognition.

This paper demonstrates an organic electrochemical transistor (OECT) as an on-site amplifier for electrochemical aptamer-based sensors, significantly enhancing sensitivity for TGF-β1 detection.

The paper identifies incomplete lineage sorting in Sulfitobacter, a marine bacterium, showing rapid speciation driven by ancestral polymorphism retention rather than adaptive selection.

This study identifies a loss-of-function mutation in OXR1 causing neurodevelopmental disorders and shows its role in regulating histone arginine methylation in brain organoids.

The paper designs a DNA nanostructure for rapid, sensitive, and inexpensive detection of SARS-CoV-2 and demonstrates its potential to inhibit viral infection.

This study shows that sensor NLRs Rpi-amr3 and Rpi-amr1 activate the helper NLR NRC2 to form a resistosome in response to Phytophthora effectors.

The paper introduces PanGu Drug Model, a deep learning architecture for drug discovery that achieves state-of-the-art results in molecule property prediction, generation, and optimization.

The paper reports the cloning of nine GR isoforms from slender African lungfish after failed attempts using existing primers, and explains the reasons for the initial failure.

This paper introduces a synthetic carbon fixation cycle in plants that fixes CO2 without RuBisCO, showing increased photosynthetic capacity in transgenic Camelina sativa.

This study identifies a unique phosphonate utilization mechanism in diatom Phaeodactylum tricornutum involving uptake via clathrin-mediated endocytosis and incorporation into membrane phospholipids.

The paper identifies a new intercellular spread mode of RSV that is virion-independent and antibody-insensitive, contributing to immune escape and viral persistence.

This study maps chromatin reprogramming and transcriptional regulation during hexaploid wheat embryogenesis, revealing epigenetic mechanisms governing cell fate and organogenesis.

This study shows that the nucleocapsid 203 mutation, combined with spike L452R, enhances SARS-CoV-2 immune evasion and fitness, contributing to the dominance of variants like Delta and Omicron.

The paper reports the structure of the human telomere C-strand fill-in preinitiation complex, revealing how CST and pol-/primase coordinate DNA synthesis.

This study identifies unconventional secretion of unglycosylated ORF8 as critical for inducing cytokine storms during SARS-CoV-2 infection by interacting with IL17RA on macrophages.

This study shows that Serum Amyloid A (SAA) worsens acetaminophen-induced liver injury by damaging sinusoidal endothelial cells and increasing platelet aggregation.

This study evaluates how well antibodies from mRNA vaccines neutralize SARS-CoV-2 variants, finding that Omicron shows the most escape but booster doses maintain moderate neutralizing activity.

This study identifies 322 viruses in 34 grasshopper species, including 202 novel species, and finds phylogenetic congruence between grasshoppers and certain viral families.

This study investigates ComFA's role in natural transformation by demonstrating its single-stranded DNA translocase activity and ATP-dependent DNA release mechanism.

This study shows ligand binding causes intracellular conformational changes in monomeric EGFR, linking extracellular and intracellular regions through the transmembrane helix.

This study shows that PD-L1 palmitoylation affects its membrane orientation and immune evasion by altering its localization and interaction with PD-1 on T cells.

This study shows azacytidine limits SARS-CoV-2 infection and protects mice by disrupting viral RNA methylation.

The paper establishes a bacterial genome and culture collection of the piglet gut microbiome, revealing new species and functional insights.