Y. Wang

This study identifies AtERG2, a mitochondrial GTPase in Arabidopsis, as essential for early embryo development, with mutants showing seed abortion and ROS accumulation.

This paper introduces a novel RNAi-based method called variable dose analysis (VDA) to detect synthetic lethal interactions, identifying four FDA-approved drugs for TSC-related tumors.

The paper analyzes genetic diversity and adaptation in indigenous Chinese cattle, identifying genes associated with environmental adaptation and confirming historical admixture patterns.

The paper introduces SHACKTeR, a method for live cell imaging of specific chromosomal regions using CRISPR/Cas9 and TetO repeats, successfully labeling 9 loci in HCT116 cells with up to 20% efficiency.

This paper identifies ponatinib as a potent treatment for SCCOHT by inhibiting multiple kinases in preclinical models.

This study shows that the gut microbiome of Nicrophorus vespilloides larvae outcompetes carcass-derived bacteria and provides resistance against the pathogen Serratia marcescens.

This paper introduces a correlation analysis framework for localization-based super-resolution microscopy to extract quantitative descriptions and biophysical parameters from coordinate-based images.

The paper identifies and characterizes two genes, CsMYB6A and CsUGT72AM1, that promote flavonoid accumulation in purple-leaf tea, with CsMYB6A activating structural genes and CsUGT72AM1 catalyzing flavonol glycosylation.

This paper reviews the origin, functioning, and degradation of the Kobresia pygmaea ecosystem in the Tibetan highlands, identifying key factors affecting its resilience and carbon dynamics.

This study identifies a Calcineurin-FoxO-MuRF1 signaling pathway that mediates Ca2+ overload-induced myofibril degradation in cardiomyocytes using zebrafish models.

The paper identifies sequences and structural requirements for efficient transcription from the first heavy-strand promoter in mtDNA, highlighting the role of TFAM's carboxy-terminal tail and HVR3.

The paper analyzes bacterial 16S rRNA gene communities from 32 D. melanogaster individuals, revealing significant inter-individual variation despite differences between substrates and locations.

The paper evaluates inhibitors of mutant IDH1 and IDH2 using biochemical and cell-based assays to identify effective compounds for cancer therapy.

This study identifies AST1, a Trihelix transcription factor in Arabidopsis, which enhances abiotic stress tolerance by binding to AGAG-box and GT motifs, regulating stress-related genes and physiological traits.

The p38 MAPK pathway coordinates cell growth and cell cycle progression by lengthening G1 in small cells, allowing them more time to grow before their next division.

This paper introduces DNA-Exchange-Imaging, a method for rapid, highly multiplexed in situ protein visualization, achieving sub-20 nm resolution and reducing imaging time from days to minutes.

This study investigates how parental care influences the transmission and persistence of gut bacteria in burying beetle larvae, finding that pre-hatch care is sufficient for symbiont transfer and that larvae become aposymbiotic during pupation.

The paper examines how plant growth regulators affect maize kernel weight under combined stress conditions, finding genotype-specific responses.

The paper develops a Bayesian method for molecular counting using localization microscopy, showing improved accuracy with multiple fluorophore labeling and applying it to quantify plasmid copy number variability in bacteria.