Author

Richard Lynn Bennett

University of FloridaORCID 0000-0002-0243-2443Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Jonathan D. LichtiD· 4 shared Alberto RivaiD· 1 shared Amin SobhiD· 1 shared Benjamin G. BarwickiD· 1 shared Benjamin PosorskeiD· 1 shared Constantine S. MitsiadesiD· 1 shared Crissandra Piper· 1 shared Daniël P. MeltersiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersCancer Biology

Jonathan D. LichtORCID

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4 papers

Recent·Most cited

A SUN1-ApoD feedback loop promotes cellular aging via microtubule-nuclear mechanotransduction

Mengqi Chen, Paige C. Wilson, Wenyao Yang, Yue Ma, Yutao Li, Xinluan Wang, Richard Lynn Bennett, Jonathan D. Licht, Gregg G. Gundersen, Wakam Chang

The paper identifies a SUN1-ApoD feedback loop that promotes cellular aging through microtubule-nuclear mechanotransduction by inducing aging-related phenotypes in fibroblasts and muscle.

bioRxiv · Sep 10, 2026 · PreprintCell Biology

A multi-step immune-competent genetic mouse model reveals phenotypic plasticity in uveal melanoma

Xiaonan Xu, Xiaoxian Liu, James Jarad Dollar, Xiao Liu, Neel Jasani, Benjamin Posorske, Sathya Neelature Sriramareddy, Vinesh Jarajapu, Jeffim N. Kuznetsoff, John H. Sinard, Richard Lynn Bennett, Jonathan D. Licht, Keiran S.M. Smalley, J. William Harbour, Xiaoqing Yu, Florian A. Karreth

This paper develops a genetically engineered mouse model of uveal melanoma that recapitulates human disease progression and immune microenvironment features, revealing phenotypic plasticity and cooperative genetic drivers.

bioRxiv · Jun 4, 2025 · PreprintCancer Biology

Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs

Wesley N. Saintilnord, Youssef A. Hegazy, Kristin V Chesnutt, Meredith Eckstein, Richard N Cassidy, Héjer Dhahri, Richard Lynn Bennett, Daniël P. Melters, Élisson Nogueira Lopes, Zhen Fu, Kin H. Lau, Darrell P. Chandler, Michael Guy Poirier, Yamini Dalal, Jonathan D. Licht, Yvonne N. Fondufe‐Mittendorf

This study shows that H2B variants alter chromatin structure and oncogenic gene expression, suggesting they may be early cancer biomarkers and therapeutic targets.

bioRxiv · Nov 18, 2024 · PreprintCancer Biology

KDM6A Regulates Immune Response Genes in Multiple Myeloma

Daphné Dupéré-Richer, Alberto Riva, Sayantan Maji, Benjamin G. Barwick, Heidi L. Casellas Román, Amin Sobh, Gabrielle Quickstad, Jianping Li, Umasankar De, Crissandra Piper, Marta Kulis, Teresa Ezponda, José Ignacio Martín-Subero, Giovanni Tonon, Weizhou Zhang, , Jonathan D. Licht

This study shows KDM6A regulates immune response genes in multiple myeloma by activating NLRC5 and CIITA, and its loss reduces MHC expression, which can be reversed by HDAC3 inhibitors.

Blood · Jul 24, 2024Peer-reviewedCancer Biology